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Something old, something new and something borrowed: emerging paradigm of insulin-like growth factor type 1 receptor (IGF-1R) signaling regulation

Cellular and molecular life sciences : CMLS, 2014-07, Vol.71 (13), p.2403-2427

2014

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Targeting the IGF-1R: The Tale of the Tortoise and the Hare

Frontiers in endocrinology (Lausanne), 2015, Vol.6, p.64-64

2015

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Selective recruitment of G protein-coupled receptor kinases (GRKs) controls signaling of the insulin-like growth factor 1 receptor

Proceedings of the National Academy of Sciences - PNAS, 2012-05, Vol.109 (18), p.7055-7060

2012

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β-Arrestin–biased agonism as the central mechanism of action for insulin-like growth factor 1 receptor–targeting antibodies in Ewing’s sarcoma

Proceedings of the National Academy of Sciences - PNAS, 2012-12, Vol.109 (50), p.20620-20625

2012

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Mdm2-Dependent Ubiquitination and Degradation of the Insulin-like Growth Factor 1 Receptor

Proceedings of the National Academy of Sciences - PNAS, 2003-07, Vol.100 (14), p.8247-8252

2003

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Correction: Differences in cutaneous melanoma treatment and patient satisfaction

PloS one, 2021-01, Vol.16 (1), p.e0246145-e0246145

2021

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Nevus-associated Lentigo Maligna and Lentigo Maligna Melanoma, Clinicopathological Features

Acta dermato-venereologica, 2024-04, Vol.104, p.adv18381-adv18381

2024

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Cyclolignans as inhibitors of the insulin-like growth factor-1 receptor and malignant cell growth

Cancer research (Chicago, Ill.), 2004, Vol.64 (1), p.236-242

2004

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Differences in cutaneous melanoma treatment and patient satisfaction

PloS one, 2018-10, Vol.13 (10), p.e0205517-e0205517

2018

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Below the Surface: IGF-1R Therapeutic Targeting and Its Endocytic Journey

Cells (Basel, Switzerland), 2019-10, Vol.8 (10), p.1223

2019

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Personalized Medicine in Malignant Melanoma: Towards Patient Tailored Treatment

Frontiers in oncology, 2018-06, Vol.8, p.202-202

2018

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The dichotomy of the Insulin-like growth factor 1 receptor: RTK and GPCR: friend or foe for cancer treatment?

Growth hormone & IGF research, 2015-02, Vol.25 (1), p.2-12

2015

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Ten-year Follow-up Study of Grenz Ray Treatment for Lentigo Maligna and Early Lentigo Maligna Melanoma

Acta dermato-venereologica, 2020-10, Vol.100 (17), p.adv00282-adv00282

2020

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The cyclolignan PPP induces activation loop-specific inhibition of tyrosine phosphorylation of the insulin-like growth factor-1 receptor. Link to the phosphatidyl inositol-3 kinase Akt apoptotic pathway

Oncogene, 2004-10, Vol.23 (47), p.7854-7862

2004

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IRS-2 deubiquitination by USP9X maintains anchorage-independent cell growth via Erk1/2 activation in prostate carcinoma cell line

Oncotarget, 2018-09, Vol.9 (74), p.33871-33883

2018

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The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells

Clinical cancer research, 2006-02, Vol.12 (4), p.1383-1391

2006

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Bullous Pemphigoid-like Eruption Triggered by Targeted Therapy for Metastatic Melanoma

Acta dermato-venereologica, 2020, Vol.100 (18), p.adv00334-adv00334

2020

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Oral Picropodophyllin (PPP) Is Well Tolerated In Vivo and Inhibits IGF-1R Expression and Growth of Uveal Melanoma

Investigative ophthalmology & visual science, 2008-06, Vol.49 (6), p.2337-2342

2008

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Insulin-Like Growth Factor Type-I Receptor-Dependent Phosphorylation of Extracellular Signal-Regulated Kinase 1/2 but not Akt (Protein Kinase B) Can Be Induced by Picropodophyllin

Molecular pharmacology, 2008-03, Vol.73 (3), p.930-939

2008

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Differential roles of SS18–SSX fusion gene and insulin-like growth factor-1 receptor in synovial sarcoma cell growth

Biochemical and biophysical research communications, 2008-04, Vol.368 (3), p.793-800

2008

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26653 Can β-arrestin isoforms control response of melanoma cells to chemotherapy?

Journal of the American Academy of Dermatology, 2021-09, Vol.85 (3), p.AB111-AB111

2021

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Correction: The cyclolignan PPP induces activation loop-specific inhibition of tyrosine phosphorylation of the insulin-like growth factor-1 receptor. Link to the phosphatidyl inositol-3 kinase/Akt apoptotic pathway

Oncogene, 2023, Vol.42 (5), p.407-408

2023

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Expression and Growth Dependency of the Insulin-Like Growth Factor I Receptor in Craniopharyngioma Cells: A Novel Therapeutic Approach

Clinical cancer research, 2005-07, Vol.11 (13), p.4674-4680

2005

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Blurring Boundaries: Receptor Tyrosine Kinases as functional G Protein-Coupled Receptors

International review of cell and molecular biology, 2018, Vol.339, p.1-40

2018

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IGF-1R is a molecular determinant for response to p53 reactivation therapy in conjunctival melanoma

Oncogene, 2022, Vol.41 (4), p.600-611

2022

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Something old, something new and something borrowed: emerging paradigm of insulin-like growth factor type 1 receptor (IGF-1R) signaling regulation

Targeting the IGF-1R: The Tale of the Tortoise and the Hare

Selective recruitment of G protein-coupled receptor kinases (GRKs) controls signaling of the insulin-like growth factor 1 receptor

β-Arrestin–biased agonism as the central mechanism of action for insulin-like growth factor 1 receptor–targeting antibodies in Ewing’s sarcoma

Mdm2-Dependent Ubiquitination and Degradation of the Insulin-like Growth Factor 1 Receptor

Correction: Differences in cutaneous melanoma treatment and patient satisfaction

Nevus-associated Lentigo Maligna and Lentigo Maligna Melanoma, Clinicopathological Features

Cyclolignans as inhibitors of the insulin-like growth factor-1 receptor and malignant cell growth

Differences in cutaneous melanoma treatment and patient satisfaction

Below the Surface: IGF-1R Therapeutic Targeting and Its Endocytic Journey

Personalized Medicine in Malignant Melanoma: Towards Patient Tailored Treatment

The dichotomy of the Insulin-like growth factor 1 receptor: RTK and GPCR: friend or foe for cancer treatment?

Ten-year Follow-up Study of Grenz Ray Treatment for Lentigo Maligna and Early Lentigo Maligna Melanoma

The cyclolignan PPP induces activation loop-specific inhibition of tyrosine phosphorylation of the insulin-like growth factor-1 receptor. Link to the phosphatidyl inositol-3 kinase Akt apoptotic pathway

IRS-2 deubiquitination by USP9X maintains anchorage-independent cell growth via Erk1/2 activation in prostate carcinoma cell line

The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells

Bullous Pemphigoid-like Eruption Triggered by Targeted Therapy for Metastatic Melanoma

Oral Picropodophyllin (PPP) Is Well Tolerated In Vivo and Inhibits IGF-1R Expression and Growth of Uveal Melanoma

Insulin-Like Growth Factor Type-I Receptor-Dependent Phosphorylation of Extracellular Signal-Regulated Kinase 1/2 but not Akt (Protein Kinase B) Can Be Induced by Picropodophyllin

Differential roles of SS18–SSX fusion gene and insulin-like growth factor-1 receptor in synovial sarcoma cell growth

26653 Can β-arrestin isoforms control response of melanoma cells to chemotherapy?

Correction: The cyclolignan PPP induces activation loop-specific inhibition of tyrosine phosphorylation of the insulin-like growth factor-1 receptor. Link to the phosphatidyl inositol-3 kinase/Akt apoptotic pathway

Expression and Growth Dependency of the Insulin-Like Growth Factor I Receptor in Craniopharyngioma Cells: A Novel Therapeutic Approach

Blurring Boundaries: Receptor Tyrosine Kinases as functional G Protein-Coupled Receptors

IGF-1R is a molecular determinant for response to p53 reactivation therapy in conjunctival melanoma

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