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Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells

Cell reports (Cambridge), 2015-12, Vol.13 (11), p.2425-2439

2015

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Genome-wide RNAi screens in human brain tumor isolates reveal a novel viability requirement for PHF5A

Genes & development, 2013-05, Vol.27 (9), p.1032-1045

2013

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BuGZ Is Required for Bub3 Stability, Bub1 Kinetochore Function, and Chromosome Alignment

Developmental cell, 2014-02, Vol.28 (3), p.282-294

2014

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In vivo loss of tumorigenicity in a patient-derived orthotopic xenograft mouse model of ependymoma

Frontiers in oncology, 2023-03, Vol.13, p.1123492

2023

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Preclinical characterization of Pan-NKG2D ligand-binding NKG2D receptor decoys

Heliyon, 2024-04, Vol.10 (7), p.e28583-e28583, Article e28583

2024

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FBXO42 activity is required to prevent mitotic arrest, spindle assembly checkpoint activation and lethality in glioblastoma and other cancers

NAR cancer, 2024-06, Vol.6 (2)

2024

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ZNF131 suppresses centrosome fragmentation in glioblastoma stem-like cells through regulation of HAUS5

Oncotarget, 2017-07, Vol.8 (30), p.48545-48562

2017

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A biobank of patient-derived pediatric brain tumor models

Nature medicine, 2018-11, Vol.24 (11), p.1752-1761

2018

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Preclinical pediatric brain tumor models for immunotherapy: Hurdles and a way forward

Neuro-oncology (Charlottesville, Va.), 2024-02, Vol.26 (2), p.226-235

2024

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Optimal therapeutic targeting by HDAC inhibition in biopsy-derived treatment-naïve diffuse midline glioma models

Neuro-oncology (Charlottesville, Va.), 2021-03, Vol.23 (3), p.376-386

2021

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Medulloblastoma recurrence and metastatic spread are independent of colony-stimulating factor 1 receptor signaling and macrophage survival

Journal of neuro-oncology, 2021-06, Vol.153 (2), p.225-237

2021

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A potent peptide-steroid conjugate accumulates in cartilage and reverses arthritis without evidence of systemic corticosteroid exposure

Science translational medicine, 2020-03, Vol.12 (533)

2020

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Target-to-background enhancement in multispectral endoscopy with background autofluorescence mitigation for quantitative molecular imaging

Journal of biomedical optics, 2014-07, Vol.19 (7), p.076014-076014

2014

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Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager

Science translational medicine, 2022-05, Vol.14 (645), p.eabn0402

2022

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Pacifastin-derived Peptides Target Tumors for Use in In Vivo Imaging

Anticancer research, 2018-01, Vol.38 (1), p.51-60

2018

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Calibration of fluorescence imaging for tumor surgical margin delineation: multistep registration of fluorescence and histological images

Journal of medical imaging (Bellingham, Wash.), 2019-04, Vol.6 (2), p.025005-025005

2019

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A technology platform to assess multiple cancer agents simultaneously within a patient's tumor

Science translational medicine, 2015-04, Vol.7 (284), p.284ra58

2015

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Abstract LB-231: An optide (optimized knottin-peptide) that inhibits tumor cell growth In vitro and accumulates in sarcoma flank tumors in vivo

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.LB-231-LB-231

2016

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ZNF131 suppresses centrosome fragmentation in glioblastoma stem-like cells through regulation of HAUS5

Oncotarget, 2017-07, Vol.8 (30), p.48545-48562

2017

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Abstract 5141: Optimizing peptide-drug conjugate delivery as an alternative to antibody-drug conjugates for solid tumors

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.5141-5141

2017

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Abstract 413: Emerging principles in synthetic lethality in glioblastoma

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.413-413

2018

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GENE-12. EMERGING PRINCIPLES OF SYNTHETIC LETHALITY IN GLIOBLASTOMA

Neuro-oncology (Charlottesville, Va.), 2017-11, Vol.19 (suppl_6), p.vi95-vi95

2017

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Abstract B14: Precision functional genomics for glioblastoma: Identifying molecular therapeutic targets using CRISPR-Cas9 and RNAi technologies in patient isolates

Molecular cancer therapeutics, 2017-10, Vol.16 (10_Supplement), p.B14-B14

2017

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Versatile tissue‐injectable hydrogels capable of the extended hydrolytic release of bioactive protein therapeutics

Bioengineering & translational medicine, 2024-04

2024

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Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells

Genome-wide RNAi screens in human brain tumor isolates reveal a novel viability requirement for PHF5A

BuGZ Is Required for Bub3 Stability, Bub1 Kinetochore Function, and Chromosome Alignment

In vivo loss of tumorigenicity in a patient-derived orthotopic xenograft mouse model of ependymoma

Preclinical characterization of Pan-NKG2D ligand-binding NKG2D receptor decoys

FBXO42 activity is required to prevent mitotic arrest, spindle assembly checkpoint activation and lethality in glioblastoma and other cancers

ZNF131 suppresses centrosome fragmentation in glioblastoma stem-like cells through regulation of HAUS5

Single-Cell Transcriptomics in Medulloblastoma Reveals Tumor-Initiating Progenitors and Oncogenic Cascades during Tumorigenesis and Relapse

A biobank of patient-derived pediatric brain tumor models

Preclinical pediatric brain tumor models for immunotherapy: Hurdles and a way forward

Optimal therapeutic targeting by HDAC inhibition in biopsy-derived treatment-naïve diffuse midline glioma models

Medulloblastoma recurrence and metastatic spread are independent of colony-stimulating factor 1 receptor signaling and macrophage survival

A potent peptide-steroid conjugate accumulates in cartilage and reverses arthritis without evidence of systemic corticosteroid exposure

Target-to-background enhancement in multispectral endoscopy with background autofluorescence mitigation for quantitative molecular imaging

Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager

Pacifastin-derived Peptides Target Tumors for Use in In Vivo Imaging

Calibration of fluorescence imaging for tumor surgical margin delineation: multistep registration of fluorescence and histological images

A technology platform to assess multiple cancer agents simultaneously within a patient's tumor

Abstract LB-231: An optide (optimized knottin-peptide) that inhibits tumor cell growth In vitro and accumulates in sarcoma flank tumors in vivo

ZNF131 suppresses centrosome fragmentation in glioblastoma stem-like cells through regulation of HAUS5

Abstract 5141: Optimizing peptide-drug conjugate delivery as an alternative to antibody-drug conjugates for solid tumors

Abstract 413: Emerging principles in synthetic lethality in glioblastoma

GENE-12. EMERGING PRINCIPLES OF SYNTHETIC LETHALITY IN GLIOBLASTOMA

Abstract B14: Precision functional genomics for glioblastoma: Identifying molecular therapeutic targets using CRISPR-Cas9 and RNAi technologies in patient isolates

Versatile tissue‐injectable hydrogels capable of the extended hydrolytic release of bioactive protein therapeutics

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