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Cleft lip and palate results from Hedgehog signaling antagonism in the mouse: Phenotypic characterization and clinical implications

Birth defects research. A Clinical and molecular teratology, 2010-04, Vol.88 (4), p.232-240

2010

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H2O2-dependent Activation of GCLC-ARE4 Reporter Occurs by Mitogen-activated Protein Kinase Pathways without Oxidation of Cellular Glutathione or Thioredoxin-1

The Journal of biological chemistry, 2004-02, Vol.279 (7), p.5837-5845

2004

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Unique and complimentary activities of the Gli transcription factors in Hedgehog signaling

Experimental cell research, 2006-07, Vol.312 (11), p.1925-1938

2006

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Hedgehog pathway responsiveness correlates with the presence of primary cilia on prostate stromal cells

BMC developmental biology, 2009-10, Vol.9 (1), p.50-50, Article 50

2009

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Identification of a variant antioxidant response element in the promoter of the human glutamate-cysteine ligase modifier subunit gene. Revision of the ARE consensus sequence

The Journal of biological chemistry, 2002-08, Vol.277 (34), p.30730-30737

2002

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Establishment and characterization of immortalized Gli-null mouse embryonic fibroblast cell lines

BMC cell biology, 2008-09, Vol.9 (1), p.49, Article 49

2008

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Sonic hedgehog signaling regulates the expression of insulin‐like growth factor binding protein‐6 during fetal prostate development

Developmental dynamics, 2005-07, Vol.233 (3), p.829-836

2005

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Synthesis and Evaluation of Nitroheterocyclic Phosphoramidates as Hypoxia-Selective Alkylating Agents

Journal of medicinal chemistry, 2000-06, Vol.43 (11), p.2258-2265

2000

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Constitutive and β-Naphthoflavone-induced Expression of the Human γ-Glutamylcysteine Synthetase Heavy Subunit Gene Is Regulated by a Distal Antioxidant Response Element/TRE Sequence

The Journal of biological chemistry, 1997-03, Vol.272 (11), p.7445-7454

1997

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Identification of a Variant Antioxidant Response Element in the Promoter of the Human Glutamate-Cysteine Ligase Modifier Subunit Gene

The Journal of biological chemistry, 2002-08, Vol.277 (34), p.30730-30737

2002

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Nitrobenzyl Phosphorodiamidates as Potential Hypoxia-Selective Alkylating Agents

Journal of medicinal chemistry, 1994-05, Vol.37 (11), p.1610-1615

1994

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Identification of a Putative Antioxidant Response Element in the 5′-Flanking Region of the Human γ-Glutamylcysteine Synthetase Heavy Subunit Gene

Biochemical and biophysical research communications, 1995-04, Vol.209 (1), p.227-233

1995

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Overlapping antioxidant response element and PMA response element sequences mediate basal and beta-naphthoflavone-induced expression of the human gamma-glutamylcysteine synthetase catalytic subunit gene

Biochemical journal, 1998-06, Vol.332 ( Pt 2) (Pt 2), p.373-381

1998

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Transfection of complementary DNAs for the heavy and light subunits of human γ-glutamylcysteine synthetase results in an elevation of intracellular glutathione and resistance to Melphalan

Cancer research (Chicago, Ill.), 1995-11, Vol.55 (21), p.4771-4775

1995

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Cloning and nucleotide sequence of a full-length cDNA for human liver γ-glutamylcysteine synthetase

Biochemical and biophysical research communications, 1992-05, Vol.185 (1), p.29-35

1992

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H2O2-dependent activation of GCLC-ARE4 reporter occurs by mitogen-activated protein kinase pathways without oxidation of cellular glutathione and thioredoxin-1. Vol. 279 (2004) 5837-5845

The Journal of biological chemistry, 2004-04, Vol.279 (15), p.15706-15706

2004

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Cytotoxicity and glutathione depletion by 1-methyl-2-nitrosoimidazole in human colon cancer cells

Biochemical pharmacology, 1989-05, Vol.38 (10), p.1667-1671

1989

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Transcriptional up-regulation of gamma-glutamylcysteine synthetase gene expression in melphalan-resistant human prostate carcinoma cells

Molecular pharmacology, 1994-11, Vol.46 (5), p.909-914

1994

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Up-regulation of γ-glutamylcysteine synthetase activity in melphalan-resistant human multiple myeloma cells expressing increased glutathione levels

Cancer chemotherapy and pharmacology, 1994-01, Vol.34 (1), p.67-71

1994

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Overlapping antioxidant response element and PMA responseelement sequences mediate basal and β-naphthoflavone-induced expression of the human γ-glutamylcysteine synthetase catalytic subunit gene

Biochemical journal, 1998-06, Vol.332 (2), p.373-381

1998

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Increased expression of γ-glutamyl transpeptidase in transfected tumor cells and its relationship to drug sensitivity

Cancer letters, 1994-12, Vol.87 (2), p.163-170

1994

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Constitutive and Î²-Naphthoflavone-induced Expression of the Human Î³-Glutamylcysteine Synthetase Heavy Subunit Gene Is Regulated by a Distal Antioxidant Response Element/TRE Sequence

The Journal of biological chemistry, 1997-03, Vol.272 (11), p.7445

1997

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Up-regulation of ?-glutamylcysteine synthetase activity in melphalan-resistant human multiple myeloma cells expressing increased glutathione levels

Cancer chemotherapy and pharmacology, 1994, Vol.34 (1), p.67-71

1994

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DNA damage induced in HT-29 colon cancer cells by exposure to 1-methyl-2-nitrosoimidazole, a reductive metabolite of 1-methyl-2-nitroimidazole

Biochemical pharmacology, 1991-12, Vol.42, p.S127-S133

1991

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Enhancement of melphalan (l-PAM) toxicity by reductive metabolites of 1-methyl-2-nitroimidazole, a model nitroimidazole chemosensitizing agent

Biochemical pharmacology, 1990-12, Vol.40 (12), p.2671-2676

1990

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Cleft lip and palate results from Hedgehog signaling antagonism in the mouse: Phenotypic characterization and clinical implications

H2O2-dependent Activation of GCLC-ARE4 Reporter Occurs by Mitogen-activated Protein Kinase Pathways without Oxidation of Cellular Glutathione or Thioredoxin-1

Unique and complimentary activities of the Gli transcription factors in Hedgehog signaling

Hedgehog pathway responsiveness correlates with the presence of primary cilia on prostate stromal cells

Identification of a variant antioxidant response element in the promoter of the human glutamate-cysteine ligase modifier subunit gene. Revision of the ARE consensus sequence

Establishment and characterization of immortalized Gli-null mouse embryonic fibroblast cell lines

Sonic hedgehog signaling regulates the expression of insulin‐like growth factor binding protein‐6 during fetal prostate development

Synthesis and Evaluation of Nitroheterocyclic Phosphoramidates as Hypoxia-Selective Alkylating Agents

Constitutive and β-Naphthoflavone-induced Expression of the Human γ-Glutamylcysteine Synthetase Heavy Subunit Gene Is Regulated by a Distal Antioxidant Response Element/TRE Sequence

Identification of a Variant Antioxidant Response Element in the Promoter of the Human Glutamate-Cysteine Ligase Modifier Subunit Gene

Nitrobenzyl Phosphorodiamidates as Potential Hypoxia-Selective Alkylating Agents

Identification of a Putative Antioxidant Response Element in the 5′-Flanking Region of the Human γ-Glutamylcysteine Synthetase Heavy Subunit Gene

Overlapping antioxidant response element and PMA response element sequences mediate basal and beta-naphthoflavone-induced expression of the human gamma-glutamylcysteine synthetase catalytic subunit gene

Transfection of complementary DNAs for the heavy and light subunits of human γ-glutamylcysteine synthetase results in an elevation of intracellular glutathione and resistance to Melphalan

Cloning and nucleotide sequence of a full-length cDNA for human liver γ-glutamylcysteine synthetase

H2O2-dependent activation of GCLC-ARE4 reporter occurs by mitogen-activated protein kinase pathways without oxidation of cellular glutathione and thioredoxin-1. Vol. 279 (2004) 5837-5845

Cytotoxicity and glutathione depletion by 1-methyl-2-nitrosoimidazole in human colon cancer cells

Transcriptional up-regulation of gamma-glutamylcysteine synthetase gene expression in melphalan-resistant human prostate carcinoma cells

Up-regulation of γ-glutamylcysteine synthetase activity in melphalan-resistant human multiple myeloma cells expressing increased glutathione levels

Overlapping antioxidant response element and PMA responseelement sequences mediate basal and β-naphthoflavone-induced expression of the human γ-glutamylcysteine synthetase catalytic subunit gene

Increased expression of γ-glutamyl transpeptidase in transfected tumor cells and its relationship to drug sensitivity

Constitutive and Î²-Naphthoflavone-induced Expression of the Human Î³-Glutamylcysteine Synthetase Heavy Subunit Gene Is Regulated by a Distal Antioxidant Response Element/TRE Sequence

Up-regulation of ?-glutamylcysteine synthetase activity in melphalan-resistant human multiple myeloma cells expressing increased glutathione levels

DNA damage induced in HT-29 colon cancer cells by exposure to 1-methyl-2-nitrosoimidazole, a reductive metabolite of 1-methyl-2-nitroimidazole

Enhancement of melphalan (l-PAM) toxicity by reductive metabolites of 1-methyl-2-nitroimidazole, a model nitroimidazole chemosensitizing agent

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