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Pyk2 modulates hippocampal excitatory synapses and contributes to cognitive deficits in a Huntington's disease model

Nature communications, 2017-05, Vol.8 (1), p.15592-15592, Article 15592

2017

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Singular Location and Signaling Profile of Adenosine A2A-Cannabinoid CB1 Receptor Heteromers in the Dorsal Striatum

Neuropsychopharmacology (New York, N.Y.), 2018-04, Vol.43 (5), p.964-977

2018

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Lack of Helios During Neural Development Induces Adult Schizophrenia-Like Behaviors Associated With Aberrant Levels of the TRIF-Recruiter Protein WDFY1

Frontiers in cellular neuroscience, 2020-05, Vol.14, p.93-93

2020

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A selective inhibitor of histone deacetylase 3 prevents cognitive deficits and suppresses striatal CAG repeat expansions in Huntington's disease mice

Scientific reports, 2017-07, Vol.7 (1), p.6082-15, Article 6082

2017

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Regulation of BDNF release by ARMS/Kidins220 through modulation of Synaptotagmin-IV levels

The Journal of neuroscience, 2018-06, Vol.38 (23), p.5415-5428

2018

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Identification of BiP as a CB1 Receptor-Interacting Protein That Fine-Tunes Cannabinoid Signaling in the Mouse Brain

The Journal of neuroscience, 2021-09, Vol.41 (38), p.7924-7941

2021

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p75NTR in Huntington's disease: beyond the basal ganglia

Oncotarget, 2016-01, Vol.7 (1), p.1-2

2016

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Mitochondrial fission in Huntington's disease mouse striatum disrupts ER-mitochondria contacts leading to disturbances in Ca2+ efflux and Reactive Oxygen Species (ROS) homeostasis

Neurobiology of disease, 2020-03, Vol.136, p.104741-104741, Article 104741

2020

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Helios modulates the maturation of a CA1 neuronal subpopulation required for spatial memory formation

Experimental neurology, 2020-01, Vol.323, p.113095-113095, Article 113095

2020

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Reduced expression of the TrkB receptor in Huntington's disease mouse models and in human brain

The European journal of neuroscience, 2006-02, Vol.23 (3), p.649-658

2006

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Early Downregulation of p75NTR by Genetic and Pharmacological Approaches Delays the Onset of Motor Deficits and Striatal Dysfunction in Huntington’s Disease Mice

Molecular neurobiology, 2019-02, Vol.56 (2), p.935-953

2019

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Pyk2 in the amygdala modulates chronic stress sequelae via PSD-95-related micro-structural changes

Translational psychiatry, 2019-01, Vol.9 (1), p.3-3, Article 3

2019

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Conditional BDNF Delivery from Astrocytes Rescues Memory Deficits, Spine Density, and Synaptic Properties in the 5xFAD Mouse Model of Alzheimer Disease

The Journal of neuroscience, 2019-03, Vol.39 (13), p.2441-2458

2019

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The GRP78-PERK axis contributes to memory and synaptic impairments in Huntington's disease R6/1 mice

Neurobiology of disease, 2023-08, Vol.184, p.106225-106225, Article 106225

2023

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Impaired TrkB-mediated ERK1/2 Activation in Huntington Disease Knock-in Striatal Cells Involves Reduced p52/p46 Shc Expression

The Journal of biological chemistry, 2010-07, Vol.285 (28), p.21537-21548

2010

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PTK2B/Pyk2 overexpression improves a mouse model of Alzheimer's disease

Experimental neurology, 2018-09, Vol.307, p.62-73

2018

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Altered m6A RNA methylation contributes to hippocampal memory deficits in Huntington’s disease mice

Cellular and molecular life sciences : CMLS, 2022-08, Vol.79 (8), p.416-416, Article 416

2022

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Cdk5-mediated mitochondrial fission: A key player in dopaminergic toxicity in Huntington's disease

Biochimica et biophysica acta. Molecular basis of disease, 2015-10, Vol.1852 (10), p.2145-2160

2015

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Dopaminergic and Glutamatergic Signaling Crosstalk in Huntington's Disease Neurodegeneration: The Role of p25/Cyclin-Dependent Kinase 5

The Journal of neuroscience, 2008-10, Vol.28 (40), p.10090-10101

2008

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Metabolic profiling for the identification of Huntington biomarkers by on‐line solid‐phase extraction capillary electrophoresis mass spectrometry combined with advanced data analysis tools

Electrophoresis, 2016-03, Vol.37 (5-6), p.795-808

2016

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Cyclin-Dependent Kinase 5 Dysfunction Contributes to Depressive-like Behaviors in Huntington’s Disease by Altering the DARPP-32 Phosphorylation Status in the Nucleus Accumbens

Biological psychiatry (1969), 2019-08, Vol.86 (3), p.196-207

2019

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Synaptic RTP801 contributes to motor-learning dysfunction in Huntington's disease

Cell death & disease, 2020-07, Vol.11 (7), p.569-569, Article 569

2020

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Evidence for Adenosine/Dopamine Receptor Interactions: Indications for Heteromerization

Neuropsychopharmacology (New York, N.Y.), 2000-10, Vol.23 (4), p.S50-S59

2000

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Pyk2 modulates hippocampal excitatory synapses and contributes to cognitive deficits in a Huntington's disease model

Modulation of dopamine D1 receptors via histamine H3 receptors is a novel therapeutic target for Huntington's disease

Singular Location and Signaling Profile of Adenosine A2A-Cannabinoid CB1 Receptor Heteromers in the Dorsal Striatum

Lack of Helios During Neural Development Induces Adult Schizophrenia-Like Behaviors Associated With Aberrant Levels of the TRIF-Recruiter Protein WDFY1

A selective inhibitor of histone deacetylase 3 prevents cognitive deficits and suppresses striatal CAG repeat expansions in Huntington's disease mice

Regulation of BDNF release by ARMS/Kidins220 through modulation of Synaptotagmin-IV levels

Identification of BiP as a CB1 Receptor-Interacting Protein That Fine-Tunes Cannabinoid Signaling in the Mouse Brain

p75NTR in Huntington's disease: beyond the basal ganglia

Modulation of dopamine D 1 receptors via histamine H 3 receptors is a novel therapeutic target for Huntington's disease

Mitochondrial fission in Huntington's disease mouse striatum disrupts ER-mitochondria contacts leading to disturbances in Ca2+ efflux and Reactive Oxygen Species (ROS) homeostasis

Helios modulates the maturation of a CA1 neuronal subpopulation required for spatial memory formation

Reduced expression of the TrkB receptor in Huntington's disease mouse models and in human brain

Early Downregulation of p75NTR by Genetic and Pharmacological Approaches Delays the Onset of Motor Deficits and Striatal Dysfunction in Huntington’s Disease Mice

Pyk2 in the amygdala modulates chronic stress sequelae via PSD-95-related micro-structural changes

Conditional BDNF Delivery from Astrocytes Rescues Memory Deficits, Spine Density, and Synaptic Properties in the 5xFAD Mouse Model of Alzheimer Disease

The GRP78-PERK axis contributes to memory and synaptic impairments in Huntington's disease R6/1 mice

Impaired TrkB-mediated ERK1/2 Activation in Huntington Disease Knock-in Striatal Cells Involves Reduced p52/p46 Shc Expression

PTK2B/Pyk2 overexpression improves a mouse model of Alzheimer's disease

Altered m6A RNA methylation contributes to hippocampal memory deficits in Huntington’s disease mice

Cdk5-mediated mitochondrial fission: A key player in dopaminergic toxicity in Huntington's disease

Dopaminergic and Glutamatergic Signaling Crosstalk in Huntington's Disease Neurodegeneration: The Role of p25/Cyclin-Dependent Kinase 5

Metabolic profiling for the identification of Huntington biomarkers by on‐line solid‐phase extraction capillary electrophoresis mass spectrometry combined with advanced data analysis tools

Cyclin-Dependent Kinase 5 Dysfunction Contributes to Depressive-like Behaviors in Huntington’s Disease by Altering the DARPP-32 Phosphorylation Status in the Nucleus Accumbens

Synaptic RTP801 contributes to motor-learning dysfunction in Huntington's disease

Evidence for Adenosine/Dopamine Receptor Interactions: Indications for Heteromerization

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