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CD22: A Regulator of Innate and Adaptive B Cell Responses and Autoimmunity

Frontiers in immunology, 2018-09, Vol.9, p.2235-2235

2018

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Anti-CD40 antibody KPL-404 inhibits T cell-mediated activation of B cells from healthy donors and autoimmune patients

Arthritis research & therapy, 2021-01, Vol.23 (1), p.5-5, Article 5

2021

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BAFF Produced by Neutrophils and Dendritic Cells Is Regulated Differently and Has Distinct Roles in Antibody Responses and Protective Immunity against West Nile Virus

The Journal of immunology (1950), 2020-03, Vol.204 (6), p.1508-1520

2020

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B cell activating factor (BAFF) from neutrophils and dendritic cells is required for protective B cell responses against Salmonella typhimurium infection

PloS one, 2021-10, Vol.16 (10), p.e0259158-e0259158

2021

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Sources of Pathogenic Nucleic Acids in Systemic Lupus Erythematosus

Frontiers in immunology, 2019-05, Vol.10, p.1028-1028

2019

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The Plasticity of Newly Formed B Cells

The Journal of immunology (1950), 2019-12, Vol.203 (12), p.3095-3104

2019

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Correction to: Anti-CD40 antibody KPL-404 inhibits T cell-mediated activation of B cells from healthy donors and autoimmune patients

Arthritis research & therapy, 2021-01, Vol.23 (1), p.36-36, Article 36

2021

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B cell-activating factor (BAFF) from dendritic cells, monocytes and neutrophils is required for B cell maturation and autoantibody production in SLE-like autoimmune disease

Frontiers in immunology, 2023-02, Vol.14, p.1050528-1050528

2023

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Extrafollicular B cell activation by marginal zone dendritic cells drives T cell-dependent antibody responses

The Journal of experimental medicine, 2012-09, Vol.209 (10), p.1825-1840

2012

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Act1, a U-box E3 ubiquitin ligase for IL-17 signaling

Science signaling, 2009-10, Vol.2 (92), p.ra63

2009

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Targeting CD22 with the monoclonal antibody epratuzumab modulates human B-cell maturation and cytokine production in response to Toll-like receptor 7 (TLR7) and B-cell receptor (BCR) signaling

Arthritis research & therapy, 2017-05, Vol.19 (1), p.91-91, Article 91

2017

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Overexpression of TLR7 promotes cell-intrinsic expansion and autoantibody production by transitional T1 B cells

The Journal of experimental medicine, 2013-11, Vol.210 (12), p.2773-2789

2013

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B-cell selection and the development of autoantibodies

Arthritis research & therapy, 2012-01, Vol.14 Suppl 4 (Suppl 4), p.S1-S1

2012

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Astrocyte-Restricted Ablation of Interleukin-17-Induced Act1-Mediated Signaling Ameliorates Autoimmune Encephalomyelitis

Immunity (Cambridge, Mass.), 2010-03, Vol.32 (3), p.414-425

2010

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Controlling immune responses by targeting antigens to dendritic cell subsets and B cells

International immunology, 2014-01, Vol.26 (1), p.3-11

2014

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Regulation of B‐lineage cells by caspase 6

Immunology and cell biology, 2018-11, Vol.96 (10), p.1072-1082

2018

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Immune complex–driven neutrophil activation and BAFF release: a link to B cell responses in SLE

Lupus science & medicine, 2022-07, Vol.9 (1), p.e000709

2022

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Targeting antigens through blood dendritic cell antigen 2 on plasmacytoid dendritic cells promotes immunologic tolerance

The Journal of immunology (1950), 2014-06, Vol.192 (12), p.5789-5801

2014

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Acid Sphingomyelinase Deficiency Prevents Diet-induced Hepatic Triacylglycerol Accumulation and Hyperglycemia in Mice

The Journal of biological chemistry, 2009-03, Vol.284 (13), p.8359-8368

2009

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High TLR7 Expression Drives the Expansion of CD19+CD24hiCD38hi Transitional B Cells and Autoantibody Production in SLE Patients

Frontiers in immunology, 2019-06, Vol.10, p.1243-1243

2019

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Spontaneous loss of tolerance of autoreactive B cells in Act1-deficient rheumatoid factor transgenic mice

The Journal of immunology (1950), 2013-09, Vol.191 (5), p.2155-2163

2013

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Elevated sphingomyelinase activity and ceramide concentration in serum of patients undergoing high dose spatially fractionated radiation treatment: Implications for endothelial apoptosis

Cancer biology & therapy, 2005-09, Vol.4 (9), p.979-986

2005

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Deficiency of Act1, a critical modulator of B cell function, leads to development of Sjögren's syndrome

European journal of immunology, 2008-08, Vol.38 (8), p.2219-2228

2008

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The adaptor molecule Act1 regulates BAFF responsiveness and self-reactive B cell selection during transitional B cell maturation

The Journal of immunology (1950), 2010-07, Vol.185 (1), p.99-109

2010

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Lack of T cells in Act1‐deficient mice results in elevated IgM‐specific autoantibodies but reduced lupus‐like disease

European journal of immunology, 2012-07, Vol.42 (7), p.1695-1705

2012

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CD22: A Regulator of Innate and Adaptive B Cell Responses and Autoimmunity

Anti-CD40 antibody KPL-404 inhibits T cell-mediated activation of B cells from healthy donors and autoimmune patients

BAFF Produced by Neutrophils and Dendritic Cells Is Regulated Differently and Has Distinct Roles in Antibody Responses and Protective Immunity against West Nile Virus

B cell activating factor (BAFF) from neutrophils and dendritic cells is required for protective B cell responses against Salmonella typhimurium infection

Sources of Pathogenic Nucleic Acids in Systemic Lupus Erythematosus

The Plasticity of Newly Formed B Cells

Correction to: Anti-CD40 antibody KPL-404 inhibits T cell-mediated activation of B cells from healthy donors and autoimmune patients

B cell-activating factor (BAFF) from dendritic cells, monocytes and neutrophils is required for B cell maturation and autoantibody production in SLE-like autoimmune disease

Extrafollicular B cell activation by marginal zone dendritic cells drives T cell-dependent antibody responses

Act1, a U-box E3 ubiquitin ligase for IL-17 signaling

Targeting CD22 with the monoclonal antibody epratuzumab modulates human B-cell maturation and cytokine production in response to Toll-like receptor 7 (TLR7) and B-cell receptor (BCR) signaling

Overexpression of TLR7 promotes cell-intrinsic expansion and autoantibody production by transitional T1 B cells

B-cell selection and the development of autoantibodies

Astrocyte-Restricted Ablation of Interleukin-17-Induced Act1-Mediated Signaling Ameliorates Autoimmune Encephalomyelitis

Controlling immune responses by targeting antigens to dendritic cell subsets and B cells

Regulation of B‐lineage cells by caspase 6

Immune complex–driven neutrophil activation and BAFF release: a link to B cell responses in SLE

Targeting antigens through blood dendritic cell antigen 2 on plasmacytoid dendritic cells promotes immunologic tolerance

Acid Sphingomyelinase Deficiency Prevents Diet-induced Hepatic Triacylglycerol Accumulation and Hyperglycemia in Mice

High TLR7 Expression Drives the Expansion of CD19+CD24hiCD38hi Transitional B Cells and Autoantibody Production in SLE Patients

Spontaneous loss of tolerance of autoreactive B cells in Act1-deficient rheumatoid factor transgenic mice

Elevated sphingomyelinase activity and ceramide concentration in serum of patients undergoing high dose spatially fractionated radiation treatment: Implications for endothelial apoptosis

Deficiency of Act1, a critical modulator of B cell function, leads to development of Sjögren's syndrome

The adaptor molecule Act1 regulates BAFF responsiveness and self-reactive B cell selection during transitional B cell maturation

Lack of T cells in Act1‐deficient mice results in elevated IgM‐specific autoantibodies but reduced lupus‐like disease

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