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Control of PD-L1 Expression by Oncogenic Activation of the AKT-mTOR Pathway in Non-Small Cell Lung Cancer

Cancer research (Chicago, Ill.), 2016-01, Vol.76 (2), p.227-238

2016

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Repositioning metformin for cancer prevention and treatment

Trends in endocrinology and metabolism, 2013-09, Vol.24 (9), p.469-480

2013

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A Uniform Computational Approach Improved on Existing Pipelines to Reveal Microbiome Biomarkers of Nonresponse to Immune Checkpoint Inhibitors

Clinical cancer research, 2021-05, Vol.27 (9), p.2571-2583

2021

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Impact of the microbiome on checkpoint inhibitor treatment in patients with non-small cell lung cancer and melanoma

EBioMedicine, 2019-10, Vol.48, p.642-647

2019

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Nelfinavir Inhibits the Growth of Small-cell Lung Cancer Cells and Patient-derived Xenograft Tumors

Anticancer research, 2021-01, Vol.41 (1), p.91-99

2021

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Nelfinavir, A Lead HIV Protease Inhibitor, Is a Broad-Spectrum, Anticancer Agent that Induces Endoplasmic Reticulum Stress, Autophagy, and Apoptosis In vitro and In vivo

Clinical cancer research, 2007-09, Vol.13 (17), p.5183-5194

2007

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Combining Nelfinavir With Chloroquine Inhibits In Vivo Growth of Human Lung Cancer Xenograft Tumors

In vivo (Athens), 2021-01, Vol.35 (1), p.141-145

2021

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Handicapping the Race to Develop Inhibitors of the Phosphoinositide 3-Kinase/Akt/Mammalian Target of Rapamycin Pathway

Clinical cancer research, 2006-02, Vol.12 (3), p.679-689

2006

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Synergistic effects of nelfinavir and bortezomib on proteotoxic death of NSCLC and multiple myeloma cells

Cell death & disease, 2012-07, Vol.3 (7), p.e353-e353

2012

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Adult-Attained Height and Colorectal Cancer Risk: A Cohort Study, Systematic Review, and Meta-Analysis

Cancer epidemiology, biomarkers & prevention, 2022-04, Vol.31 (4), p.783-792

2022

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Tobacco components stimulate Akt-dependent proliferation and NFκB-dependent survival in lung cancer cells

Carcinogenesis (New York), 2005-07, Vol.26 (7), p.1182-1195

2005

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Nelfinavir, a new anti-cancer drug with pleiotropic effects and many paths to autophagy

Autophagy, 2008-01, Vol.4 (1), p.107-109

2008

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Loss of cytoplasmic CDK1 predicts poor survival in human lung cancer and confers chemotherapeutic resistance

PloS one, 2011-08, Vol.6 (8), p.e23849

2011

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Inhibition of the phosphatidylinositol 3-kinase/akt/mammalian target of rapamycin pathway but not the MEK/ERK pathway attenuates laminin-mediated small cell lung cancer cellular survival and resistance to imatinib mesylate or chemotherapy

Cancer research (Chicago, Ill.), 2005-09, Vol.65 (18), p.8423-8432

2005

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Rapamycin sensitizes cancer cells to growth inhibition by the PARP inhibitor olaparib

Oncotarget, 2017-10, Vol.8 (50), p.87044-87053

2017

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Rapamycin downregulates thymidylate synthase and potentiates the activity of pemetrexed in non-small cell lung cancer

Oncotarget, 2014-02, Vol.5 (4), p.1062-1070

2014

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Perifosine: Update on a novel Akt inhibitor

Current oncology reports, 2009-03, Vol.11 (2), p.102-110

2009

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Spectrum of activity and molecular correlates of response to phosphatidylinositol ether lipid analogues, novel lipid-based inhibitors of Akt

Molecular cancer therapeutics, 2006-03, Vol.5 (3), p.713-722

2006

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Natural Inhibitors of Carcinogenesis

Planta medica, 2004-08, Vol.70 (8), p.691-705

2004

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Inhibition of the NOTCH and mTOR pathways by nelfinavir as a novel treatment for T cell acute lymphoblastic leukemia

International journal of oncology, 2023-11, Vol.63 (5), Article 128

2023

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The chemopreventive agent myoinositol inhibits Akt and extracellular signal-regulated kinase in bronchial lesions from heavy smokers

Cancer prevention research (Philadelphia, Pa.), 2009-04, Vol.2 (4), p.370-376

2009

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The development of phosphatidylinositol ether lipid analogues as inhibitors of the serine/threonine kinase, Akt

Expert opinion on investigational drugs, 2004-07, Vol.13 (7), p.787-797

2004

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Murine fecal microbiota transfer models selectively colonize human microbes and reveal transcriptional programs associated with response to neoadjuvant checkpoint inhibitors

Cancer Immunology, Immunotherapy, 2022-10, Vol.71 (10), p.2405-2420

2022

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Ceramide mediates nanovesicle shedding and cell death in response to phosphatidylinositol ether lipid analogs and perifosine

Cell death & disease, 2012-07, Vol.3 (7), p.e340-e340

2012

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Unpreserved lidocaine to control discomfort during cataract surgery using topical anesthesia

Journal of cataract and refractive surgery, 1997-05, Vol.23 (4), p.545-550

1997

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Control of PD-L1 Expression by Oncogenic Activation of the AKT-mTOR Pathway in Non-Small Cell Lung Cancer

Repositioning metformin for cancer prevention and treatment

A Uniform Computational Approach Improved on Existing Pipelines to Reveal Microbiome Biomarkers of Nonresponse to Immune Checkpoint Inhibitors

Impact of the microbiome on checkpoint inhibitor treatment in patients with non-small cell lung cancer and melanoma

Nelfinavir Inhibits the Growth of Small-cell Lung Cancer Cells and Patient-derived Xenograft Tumors

Nelfinavir, A Lead HIV Protease Inhibitor, Is a Broad-Spectrum, Anticancer Agent that Induces Endoplasmic Reticulum Stress, Autophagy, and Apoptosis In vitro and In vivo

Combining Nelfinavir With Chloroquine Inhibits In Vivo Growth of Human Lung Cancer Xenograft Tumors

Handicapping the Race to Develop Inhibitors of the Phosphoinositide 3-Kinase/Akt/Mammalian Target of Rapamycin Pathway

Synergistic effects of nelfinavir and bortezomib on proteotoxic death of NSCLC and multiple myeloma cells

Adult-Attained Height and Colorectal Cancer Risk: A Cohort Study, Systematic Review, and Meta-Analysis

Tobacco components stimulate Akt-dependent proliferation and NFκB-dependent survival in lung cancer cells

Nelfinavir, a new anti-cancer drug with pleiotropic effects and many paths to autophagy

Loss of cytoplasmic CDK1 predicts poor survival in human lung cancer and confers chemotherapeutic resistance

Inhibition of the phosphatidylinositol 3-kinase/akt/mammalian target of rapamycin pathway but not the MEK/ERK pathway attenuates laminin-mediated small cell lung cancer cellular survival and resistance to imatinib mesylate or chemotherapy

Rapamycin sensitizes cancer cells to growth inhibition by the PARP inhibitor olaparib

Rapamycin downregulates thymidylate synthase and potentiates the activity of pemetrexed in non-small cell lung cancer

Perifosine: Update on a novel Akt inhibitor

Spectrum of activity and molecular correlates of response to phosphatidylinositol ether lipid analogues, novel lipid-based inhibitors of Akt

Natural Inhibitors of Carcinogenesis

Inhibition of the NOTCH and mTOR pathways by nelfinavir as a novel treatment for T cell acute lymphoblastic leukemia

The chemopreventive agent myoinositol inhibits Akt and extracellular signal-regulated kinase in bronchial lesions from heavy smokers

The development of phosphatidylinositol ether lipid analogues as inhibitors of the serine/threonine kinase, Akt

Murine fecal microbiota transfer models selectively colonize human microbes and reveal transcriptional programs associated with response to neoadjuvant checkpoint inhibitors

Ceramide mediates nanovesicle shedding and cell death in response to phosphatidylinositol ether lipid analogs and perifosine

Unpreserved lidocaine to control discomfort during cataract surgery using topical anesthesia

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