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Ruthenium(II) polypyridyl complexes and DNA--from structural probes to cellular imaging and therapeutics

Chemical Society reviews, 2012-04, Vol.41 (8), p.3179-3192

2012

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Transition metal compounds as cancer radiosensitizers

Chemical Society reviews, 2019-01, Vol.48 (2), p.54-557

2019

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Targeted radionuclide therapy in combined-modality regimens

The lancet oncology, 2017-07, Vol.18 (7), p.e414-e423

2017

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A ruthenium( II ) polypyridyl complex for direct imaging of DNA structure in living cells

Nature chemistry, 2009-11, Vol.1 (8), p.662-667

2009

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Dinuclear Ruthenium(II) Complexes as Two-Photon, Time-Resolved Emission Microscopy Probes for Cellular DNA

Angewandte Chemie (International ed.), 2014-03, Vol.53 (13), p.3367-3371

International ed. in English, 2014

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Progress in Mesoporous Silica Nanoparticles as Drug Delivery Agents for Cancer Treatment

Pharmaceutics, 2021-01, Vol.13 (2), p.152

2021

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Subcellular Targeting of Theranostic Radionuclides

Frontiers in pharmacology, 2018-09, Vol.9, p.996-996

2018

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Synergy of ruthenium metallo-intercalator, [Ru(dppz) 2 (PIP)] 2+ , with PARP inhibitor Olaparib in non-small cell lung cancer cells

Scientific reports, 2023-01, Vol.13 (1), p.1456-15, Article 1456

2023

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Radiolabeled Oligonucleotides Targeting the RNA Subunit of Telomerase Inhibit Telomerase and Induce DNA Damage in Telomerase-Positive Cancer Cells

Cancer research (Chicago, Ill.), 2019-09, Vol.79 (18), p.4627-4637

2019

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Synthesis and Optimization of Mesoporous Silica Nanoparticles for Ruthenium Polypyridyl Drug Delivery

Pharmaceutics, 2021-01, Vol.13 (2), p.150

2021

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A Multifunctional Light Switch: DNA Binding and Cleavage Properties of a Heterobimetallic Ruthenium-Rhenium Dipyridophenazine Complex

Angewandte Chemie (International ed.), 2007-01, Vol.46 (20), p.3686-3688

2007

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Live Cell Luminescence Imaging As a Function of Delivery Mechanism

Chembiochem : a European journal of chemical biology, 2011-03, Vol.12 (4), p.548-551

2011

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Combining PARP Inhibition with Platinum, Ruthenium or Gold Complexes for Cancer Therapy

ChemMedChem, 2020-11, Vol.15 (22), p.2121-2135

2020

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111 In-labelled polymeric nanoparticles incorporating a ruthenium-based radiosensitizer for EGFR-targeted combination therapy in oesophageal cancer cells

Nanoscale, 2018-06, Vol.10 (22), p.10596-10608

2018

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A Ruthenium(II) Polypyridyl Complex Disrupts Actin Cytoskeleton Assembly and Blocks Cytokinesis

Angewandte Chemie (International ed.), 2022-07, Vol.61 (27), p.e202117449-n/a

International ed. in English, 2022

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Multimodal Super-resolution Optical Microscopy Using a Transition-Metal-Based Probe Provides Unprecedented Capabilities for Imaging Both Nuclear Chromatin and Mitochondria

Journal of the American Chemical Society, 2017-11, Vol.139 (44), p.15907-15913

2017

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Ruthenium(II) Polypyridyl Complexes as FRET Donors: Structure- and Sequence-Selective DNA-Binding and Anticancer Properties

Journal of the American Chemical Society, 2023-01, Vol.145 (2), p.1236-1246

2023

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Using Nanoscopy To Probe the Biological Activity of Antimicrobial Leads That Display Potent Activity against Pathogenic, Multidrug Resistant, Gram-Negative Bacteria

ACS nano, 2019-05, Vol.13 (5), p.5133-5146

2019

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A ruthenium polypyridyl intercalator stalls DNA replication forks, radiosensitizes human cancer cells and is enhanced by Chk1 inhibition

Scientific reports, 2016-08, Vol.6 (1), p.31973, Article 31973

2016

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A Cytostatic Ruthenium(II)-Platinum(II) Bis(terpyridyl) Anticancer Complex That Blocks Entry into S Phase by Up-regulating p27(KIP1)

Chemistry : a European journal, 2015-06, Vol.21 (25), p.9185-9197

2015

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Indium-111 labelling of liposomal HEGF for radionuclide delivery via ultrasound-induced cavitation

Journal of controlled release, 2020-03, Vol.319, p.222-233

2020

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Discovery of Ruthenium(II) Metallocompound and Olaparib Synergy for Cancer Combination Therapy

Journal of medicinal chemistry, 2023-05, Vol.66 (10), p.6922-6937

2023

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Tuning the Cellular Uptake Properties of Luminescent Heterobimetallic Iridium(III)-Ruthenium(II) DNA Imaging Probes

Chemistry : a European journal, 2014-10, Vol.20 (43), p.14004-14011

2014

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Oligonucleotide-Functionalized Gold Nanoparticles for Synchronous Telomerase Inhibition, Radiosensitization, and Delivery of Theranostic Radionuclides

Molecular pharmaceutics, 2021-10, Vol.18 (10), p.3820-3831

2021

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Ruthenium(II) Metallo-intercalators: DNA Imaging and Cytotoxicity

Chembiochem : a European journal of chemical biology, 2011-04, Vol.12 (6), p.877-880

2011

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Ruthenium(II) polypyridyl complexes and DNA--from structural probes to cellular imaging and therapeutics

Transition metal compounds as cancer radiosensitizers

Targeted radionuclide therapy in combined-modality regimens

A ruthenium( II ) polypyridyl complex for direct imaging of DNA structure in living cells

Dinuclear Ruthenium(II) Complexes as Two-Photon, Time-Resolved Emission Microscopy Probes for Cellular DNA

Progress in Mesoporous Silica Nanoparticles as Drug Delivery Agents for Cancer Treatment

Subcellular Targeting of Theranostic Radionuclides

Synergy of ruthenium metallo-intercalator, [Ru(dppz) 2 (PIP)] 2+ , with PARP inhibitor Olaparib in non-small cell lung cancer cells

Radiolabeled Oligonucleotides Targeting the RNA Subunit of Telomerase Inhibit Telomerase and Induce DNA Damage in Telomerase-Positive Cancer Cells

Synthesis and Optimization of Mesoporous Silica Nanoparticles for Ruthenium Polypyridyl Drug Delivery

A Multifunctional Light Switch: DNA Binding and Cleavage Properties of a Heterobimetallic Ruthenium-Rhenium Dipyridophenazine Complex

Live Cell Luminescence Imaging As a Function of Delivery Mechanism

Combining PARP Inhibition with Platinum, Ruthenium or Gold Complexes for Cancer Therapy

111 In-labelled polymeric nanoparticles incorporating a ruthenium-based radiosensitizer for EGFR-targeted combination therapy in oesophageal cancer cells

A Ruthenium(II) Polypyridyl Complex Disrupts Actin Cytoskeleton Assembly and Blocks Cytokinesis

Multimodal Super-resolution Optical Microscopy Using a Transition-Metal-Based Probe Provides Unprecedented Capabilities for Imaging Both Nuclear Chromatin and Mitochondria

Ruthenium(II) Polypyridyl Complexes as FRET Donors: Structure- and Sequence-Selective DNA-Binding and Anticancer Properties

Using Nanoscopy To Probe the Biological Activity of Antimicrobial Leads That Display Potent Activity against Pathogenic, Multidrug Resistant, Gram-Negative Bacteria

A ruthenium polypyridyl intercalator stalls DNA replication forks, radiosensitizes human cancer cells and is enhanced by Chk1 inhibition

A Cytostatic Ruthenium(II)-Platinum(II) Bis(terpyridyl) Anticancer Complex That Blocks Entry into S Phase by Up-regulating p27(KIP1)

Indium-111 labelling of liposomal HEGF for radionuclide delivery via ultrasound-induced cavitation

Discovery of Ruthenium(II) Metallocompound and Olaparib Synergy for Cancer Combination Therapy

Tuning the Cellular Uptake Properties of Luminescent Heterobimetallic Iridium(III)-Ruthenium(II) DNA Imaging Probes

Oligonucleotide-Functionalized Gold Nanoparticles for Synchronous Telomerase Inhibition, Radiosensitization, and Delivery of Theranostic Radionuclides

Ruthenium(II) Metallo-intercalators: DNA Imaging and Cytotoxicity

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