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Molecular pathogenesis of chronic lymphocytic leukaemia

British journal of haematology, 2019-09, Vol.186 (5), p.668-684

2019

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Insight into del17p low‐frequency subclones in chronic lymphocytic leukaemia (CLL): data from the Australasian Leukaemia and Lymphoma Group (ALLG)/CLL Australian Research Consortium (CLLARC) CLL5 trial

British journal of haematology, 2021-05, Vol.193 (3), p.556-560

2021

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The effect of HYPE knock-out on the AMPylome of human OSU-CLL leukemia cells

Leukemia & lymphoma, 2024-02, Vol.65 (2), p.242-249

2024

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Immune failure, infection and survival in chronic lymphocytic leukemia

Haematologica (Roma), 2018-07, Vol.103 (7), p.e329-e329

2018

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MEK1/2 inhibition by binimetinib is effective as a single agent and potentiates the actions of Venetoclax and ABT‐737 under conditions that mimic the chronic lymphocytic leukaemia (CLL) tumour microenvironment

British journal of haematology, 2018-08, Vol.182 (3), p.360-372

2018

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Humoral immune failure defined by immunoglobulin class and immunoglobulin G subclass deficiency is associated with shorter treatment‐free and overall survival in Chronic Lymphocytic Leukaemia

British journal of haematology, 2018-04, Vol.181 (1), p.97-101

2018

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The dual inhibitor of the phosphoinositol‐3 and PIM kinases, IBL‐202, is effective against chronic lymphocytic leukaemia cells under conditions that mimic the hypoxic tumour microenvironment

British journal of haematology, 2018-09, Vol.182 (5), p.654-669

2018

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Modeling the chronic lymphocytic leukemia microenvironment in vitro

Leukemia & lymphoma, 2017-02, Vol.58 (2), p.266-279

2017

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Of Mouse and Man: Cross-Species Characterization of Hypertensive Cardiac Remodeling

International journal of molecular sciences, 2022-07, Vol.23 (14), p.7709

2022

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Probiotics, dendritic cells and bladder cancer

BJU international, 2012-06, Vol.109 (11), p.1594-1597

2012

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Fludarabine nucleoside induces major changes in the p53 interactome in human B-lymphoid cancer cell lines

Nucleosides, nucleotides & nucleic acids, 2022, Vol.41 (3), p.314-320

2022

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Extensive surface protein profiles of extracellular vesicles from cancer cells may provide diagnostic signatures from blood samples

Journal of extracellular vesicles, 2016-01, Vol.5 (1), p.25355-n/a

2016

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The CIpP activator, TR-57, is highly effective as a single agent and in combination with venetoclax against CLL cells in vitro

Leukemia & lymphoma, 2024-05, Vol.65 (5), p.585-597

2024

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Ibrutinib and idelalisib block immunophenotypic changes associated with the adhesion and activation of CLL cells in the tumor microenvironment

Leukemia & lymphoma, 2018-08, Vol.59 (8), p.1927-1937

2018

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Two novel activating mutations in the Wiskott-Aldrich syndrome protein result in congenital neutropenia

Blood, 2006-10, Vol.108 (7), p.2182-2189

2006

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Dual inhibition of MEK1/2 and AKT by binimetinib and MK2206 induces apoptosis of chronic lymphocytic leukemia cells under conditions that mimic the tumor microenvironment

Leukemia & lymphoma, 2019-06, Vol.60 (7), p.1632-1643

2019

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Disease-associated missense mutations in the EVH1 domain disrupt intrinsic WASp function causing dysregulated actin dynamics and impaired dendritic cell migration

Blood, 2013-01, Vol.121 (1), p.72-84

2013

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Unregulated actin polymerization by WASp causes defects of mitosis and cytokinesis in X-linked neutropenia

The Journal of experimental medicine, 2007-09, Vol.204 (9), p.2213-2224

2007

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Mechanisms of WASp-mediated hematologic and immunologic disease

Blood, 2004-12, Vol.104 (12), p.3454-3462

2004

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The MEK1/2 inhibitor, MEKi-1, induces cell death in chronic lymphocytic leukemia cells under conditions that mimic the tumor microenvironment and is synergistic with fludarabine

Leukemia & lymphoma, 2015-12, Vol.56 (12), p.3407-3417

2015

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Immunoglobulin G subclass deficiency and infection risk in 150 patients with chronic lymphocytic leukemia

Leukemia & lymphoma, 2013-01, Vol.54 (1), p.99-104

2013

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Outcomes for critical illness in children with cancer: Analysis of risk factors for adverse outcome and resource utilization from a specialized center in Mexico

Frontiers in oncology, 2022-11, Vol.12, p.1038879-1038879

2022

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Replication-independent nucleosome exchange is enhanced by local and specific acetylation of histone H4

Nucleic acids research, 2013-02, Vol.41 (4), p.2228-2238

2013

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Phosphorylation of WAVE2 by MAP kinases regulates persistent cell migration and polarity

Journal of cell science, 2007-12, Vol.120 (Pt 23), p.4144-4154

2007

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Protein profiles distinguish stable and progressive chronic lymphocytic leukemia

Leukemia & lymphoma, 2016-05, Vol.57 (5), p.1033-1043

2016

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Molecular pathogenesis of chronic lymphocytic leukaemia

Insight into del17p low‐frequency subclones in chronic lymphocytic leukaemia (CLL): data from the Australasian Leukaemia and Lymphoma Group (ALLG)/CLL Australian Research Consortium (CLLARC) CLL5 trial

The effect of HYPE knock-out on the AMPylome of human OSU-CLL leukemia cells

Immune failure, infection and survival in chronic lymphocytic leukemia

MEK1/2 inhibition by binimetinib is effective as a single agent and potentiates the actions of Venetoclax and ABT‐737 under conditions that mimic the chronic lymphocytic leukaemia (CLL) tumour microenvironment

Humoral immune failure defined by immunoglobulin class and immunoglobulin G subclass deficiency is associated with shorter treatment‐free and overall survival in Chronic Lymphocytic Leukaemia

The dual inhibitor of the phosphoinositol‐3 and PIM kinases, IBL‐202, is effective against chronic lymphocytic leukaemia cells under conditions that mimic the hypoxic tumour microenvironment

Modeling the chronic lymphocytic leukemia microenvironment in vitro

Of Mouse and Man: Cross-Species Characterization of Hypertensive Cardiac Remodeling

Probiotics, dendritic cells and bladder cancer

Fludarabine nucleoside induces major changes in the p53 interactome in human B-lymphoid cancer cell lines

Extensive surface protein profiles of extracellular vesicles from cancer cells may provide diagnostic signatures from blood samples

The CIpP activator, TR-57, is highly effective as a single agent and in combination with venetoclax against CLL cells in vitro

Ibrutinib and idelalisib block immunophenotypic changes associated with the adhesion and activation of CLL cells in the tumor microenvironment

Two novel activating mutations in the Wiskott-Aldrich syndrome protein result in congenital neutropenia

Dual inhibition of MEK1/2 and AKT by binimetinib and MK2206 induces apoptosis of chronic lymphocytic leukemia cells under conditions that mimic the tumor microenvironment

Disease-associated missense mutations in the EVH1 domain disrupt intrinsic WASp function causing dysregulated actin dynamics and impaired dendritic cell migration

Unregulated actin polymerization by WASp causes defects of mitosis and cytokinesis in X-linked neutropenia

Mechanisms of WASp-mediated hematologic and immunologic disease

The MEK1/2 inhibitor, MEKi-1, induces cell death in chronic lymphocytic leukemia cells under conditions that mimic the tumor microenvironment and is synergistic with fludarabine

Immunoglobulin G subclass deficiency and infection risk in 150 patients with chronic lymphocytic leukemia

Outcomes for critical illness in children with cancer: Analysis of risk factors for adverse outcome and resource utilization from a specialized center in Mexico

Replication-independent nucleosome exchange is enhanced by local and specific acetylation of histone H4

Phosphorylation of WAVE2 by MAP kinases regulates persistent cell migration and polarity

Protein profiles distinguish stable and progressive chronic lymphocytic leukemia

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