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The Role of Vesicle Trafficking Defects in the Pathogenesis of Prion and Prion-Like Disorders

International journal of molecular sciences, 2020-10, Vol.21 (19), p.7016

2020

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Chronic wasting disease: Emerging prions and their potential risk

PLoS pathogens, 2017-11, Vol.13 (11), p.e1006619-e1006619

2017

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The prion-like phenomenon in Alzheimer's disease: Evidence of pathology transmission in humans

PLoS pathogens, 2020-10, Vol.16 (10), p.e1009004-e1009004

2020

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Early and Non-Invasive Detection of Chronic Wasting Disease Prions in Elk Feces by Real-Time Quaking Induced Conversion

PloS one, 2016-11, Vol.11 (11), p.e0166187-e0166187

2016

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Cervid Prion Protein Polymorphisms: Role in Chronic Wasting Disease Pathogenesis

International journal of molecular sciences, 2021-02, Vol.22 (5), p.2271

2021

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Cerebral organoids as a new model for prion disease

PLoS pathogens, 2021-07, Vol.17 (7), p.e1009747-e1009747

2021

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Severe Acute Respiratory Syndrome Coronavirus Replication Is Severely Impaired by MG132 due to Proteasome-Independent Inhibition of M-Calpain

Journal of Virology, 2012-09, Vol.86 (18), p.10112-10122

2012

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Short and sweet: How glycans impact prion conversion, cofactor interactions, and cross-species transmission

PLoS pathogens, 2021-01, Vol.17 (1), p.e1009123-e1009123

2021

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Extraneural infection route restricts prion conformational variability and attenuates the impact of quaternary structure on infectivity

PLoS pathogens, 2024-07, Vol.20 (7), p.e1012370

2024

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Identification of a homology-independent linchpin domain controlling mouse and bank vole prion protein conversion

PLoS pathogens, 2020-09, Vol.16 (9), p.e1008875-e1008875

2020

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New and distinct chronic wasting disease strains associated with cervid polymorphism at codon 116 of the Prnp gene

PLoS pathogens, 2021-07, Vol.17 (7), p.e1009795-e1009795

2021

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Chronic wasting disease prions in mule deer interdigital glands

PloS one, 2022-10, Vol.17 (10), p.e0275375-e0275375

2022

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Autophagy pathways in the treatment of prion diseases

Current opinion in pharmacology, 2019-02, Vol.44, p.46-52

2019

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Cellulose ether treatment inhibits amyloid beta aggregation, neuroinflammation and cognitive deficits in transgenic mouse model of Alzheimer's disease

Journal of neuroinflammation, 2023-07, Vol.20 (1), p.177-177, Article 177

2023

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Preparation and Characterization of Cellulose Ether Liposomes for the Inhibition of Prion Formation in Prion-Infected Cells

Journal of pharmaceutical sciences, 2019-08, Vol.108 (8), p.2814-2820

2019

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Chronic wasting disease - A prion disease through a One Health lens

Canadian veterinary journal, 2022-04, Vol.63 (4), p.431-433

Gilch, Sabine

2022

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Destabilizing polymorphism in cervid prion protein hydrophobic core determines prion conformation and conversion efficiency

PLoS pathogens, 2017-08, Vol.13 (8), p.e1006553-e1006553

2017

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The celecoxib derivatives AR-12 and AR-14 induce autophagy and clear prion-infected cells from prions

Scientific reports, 2017-12, Vol.7 (1), p.17565-12, Article 17565

2017

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Gene-Edited Cell Models to Study Chronic Wasting Disease

Viruses, 2022-03, Vol.14 (3), p.609

2022

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Oral administration of repurposed drug targeting Cyp46A1 increases survival times of prion infected mice

Acta neuropathologica communications, 2021-04, Vol.9 (1), p.58-58, Article 58

2021

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Early detection of chronic wasting disease prions in urine of pre-symptomatic deer by real-time quaking-induced conversion assay

Prion, 2013-05, Vol.7 (3), p.253-258

2013

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Propagation of PrPSc in mice reveals impact of aggregate composition on prion disease pathogenesis

Communications biology, 2023-11, Vol.6 (1), p.1162-1162, Article 1162

2023

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Combining autophagy stimulators and cellulose ethers for therapy against prion disease

Prion, 2019-01, Vol.13 (1), p.185-196

2019

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Prion protein interaction with stress-inducible protein 1 enhances neuronal protein synthesis via mTOR

Proceedings of the National Academy of Sciences - PNAS, 2010-07, Vol.107 (29), p.13147-13152

2010

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Proteasomal Dysfunction and Endoplasmic Reticulum Stress Enhance Trafficking of Prion Protein Aggregates through the Secretory Pathway and Increase Accumulation of Pathologic Prion Protein

The Journal of biological chemistry, 2011-09, Vol.286 (39), p.33942-33953

2011

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The Role of Vesicle Trafficking Defects in the Pathogenesis of Prion and Prion-Like Disorders

Chronic wasting disease: Emerging prions and their potential risk

The prion-like phenomenon in Alzheimer's disease: Evidence of pathology transmission in humans

Early and Non-Invasive Detection of Chronic Wasting Disease Prions in Elk Feces by Real-Time Quaking Induced Conversion

Cervid Prion Protein Polymorphisms: Role in Chronic Wasting Disease Pathogenesis

Cerebral organoids as a new model for prion disease

Severe Acute Respiratory Syndrome Coronavirus Replication Is Severely Impaired by MG132 due to Proteasome-Independent Inhibition of M-Calpain

Short and sweet: How glycans impact prion conversion, cofactor interactions, and cross-species transmission

Extraneural infection route restricts prion conformational variability and attenuates the impact of quaternary structure on infectivity

Identification of a homology-independent linchpin domain controlling mouse and bank vole prion protein conversion

New and distinct chronic wasting disease strains associated with cervid polymorphism at codon 116 of the Prnp gene

Chronic wasting disease prions in mule deer interdigital glands

Autophagy pathways in the treatment of prion diseases

Cellulose ether treatment inhibits amyloid beta aggregation, neuroinflammation and cognitive deficits in transgenic mouse model of Alzheimer's disease

Preparation and Characterization of Cellulose Ether Liposomes for the Inhibition of Prion Formation in Prion-Infected Cells

Chronic wasting disease - A prion disease through a One Health lens

Destabilizing polymorphism in cervid prion protein hydrophobic core determines prion conformation and conversion efficiency

The celecoxib derivatives AR-12 and AR-14 induce autophagy and clear prion-infected cells from prions

Gene-Edited Cell Models to Study Chronic Wasting Disease

Oral administration of repurposed drug targeting Cyp46A1 increases survival times of prion infected mice

Early detection of chronic wasting disease prions in urine of pre-symptomatic deer by real-time quaking-induced conversion assay

Propagation of PrPSc in mice reveals impact of aggregate composition on prion disease pathogenesis

Combining autophagy stimulators and cellulose ethers for therapy against prion disease

Prion protein interaction with stress-inducible protein 1 enhances neuronal protein synthesis via mTOR

Proteasomal Dysfunction and Endoplasmic Reticulum Stress Enhance Trafficking of Prion Protein Aggregates through the Secretory Pathway and Increase Accumulation of Pathologic Prion Protein

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