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Freeze-Dry Microscopy of Protein/Sugar Mixtures: Drying Behavior, Interpretation of Collapse Temperatures and a Comparison to Corresponding Glass Transition Data

Journal of pharmaceutical sciences, 2009-09, Vol.98 (9), p.3072-3087

2009

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Impact of Payload Hydrophobicity on the Stability of Antibody–Drug Conjugates

Molecular pharmaceutics, 2018-07, Vol.15 (7), p.2656-2664

2018

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Freeze Drying of l-Arginine/Sucrose-Based Protein Formulations, Part I: Influence of Formulation and Arginine Counter Ion on the Critical Formulation Temperature, Product Performance and Protein Stability

Journal of pharmaceutical sciences, 2015-07, Vol.104 (7), p.2345-2358

2015

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Freeze-Drying of l-Arginine/Sucrose-Based Protein Formulations, Part 2: Optimization of Formulation Design and Freeze-Drying Process Conditions for an l-Arginine Chloride-Based Protein Formulation System

Journal of pharmaceutical sciences, 2015-12, Vol.104 (12), p.4241-4256

2015

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Evaluation of a New Wireless Temperature Remote Interrogation System (TEMPRIS) to Measure Product Temperature During Freeze Drying

AAPS PharmSciTech, 2008, Vol.9 (3), p.729-739

2008

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Predictive Screening Tools Used in High-Concentration Protein Formulation Development

Journal of pharmaceutical sciences, 2018-03, Vol.107 (3), p.772-777

2018

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Use of manometric temperature measurement (MTM) and SMART™ freeze dryer technology for development of an optimized freeze‐drying cycle

Journal of pharmaceutical sciences, 2007-12, Vol.96 (12), p.3402-3418

2007

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Molded Vial Manufacturing and Its Impact on Heat Transfer during Freeze-Drying: Vial Geometry Considerations

AAPS PharmSciTech, 2021-01, Vol.22 (2), p.57-57, Article 57

2021

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Factors Influencing the Retention of Organic Solvents in Products Freeze-Dried From Co-Solvent Systems

Journal of pharmaceutical sciences, 2018-08, Vol.107 (8), p.2005-2012

2018

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Evaluation of Packaging Materials in Freeze-Drying: Use of Polymer Caps and Nested Vials and Their Impact on Process and Product Attributes

AAPS PharmSciTech, 2021-02, Vol.22 (3), p.82-82, Article 82

2021

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Merits and Limitations of Dynamic Vapor Sorption Studies on the Morphology and Physicochemical State of Freeze-Dried Products

Journal of pharmaceutical sciences, 2018-08, Vol.107 (8), p.2179-2191

2018

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Gravimetric Measurement of Momentary Drying Rate of Spray Freeze-Dried Powders in Vials

Journal of pharmaceutical sciences, 2009-09, Vol.98 (9), p.3447-3455

2009

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Evaluation of tunable diode laser absorption spectroscopy for in‐process water vapor mass flux measurements during freeze drying

Journal of pharmaceutical sciences, 2007-07, Vol.96 (7), p.1776-1793

2007

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Design of Vacuum-Induced Freezing Protocols for High Fill Volume Formulations in Freeze-Drying: A Strategic Approach

Journal of pharmaceutical sciences, 2020-10, Vol.109 (10), p.3035-3044

2020

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Investigation of Two Different Pressure-Based Controlled Ice Nucleation Techniques in Freeze-Drying: The Integral Role of Shelf Temperature After Nucleation in Process Performance and Product Quality

Journal of pharmaceutical sciences, 2020-09, Vol.109 (9), p.2746-2756

2020

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Agitation-Induced Aggregation of Lysine- And Interchain Cysteine-Linked Antibody-Drug Conjugates

Journal of pharmaceutical sciences, 2024-05, Vol.113 (5), p.1265-1274

2024

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“Negative” Impact: The Role of Payload Charge in the Physicochemical Stability of Auristatin Antibody–Drug Conjugates

Journal of pharmaceutical sciences, 2024-08, Vol.113 (8), p.2433-2442

2024

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Evaluating the Potential of Cyclodextrins in Reducing Aggregation of Antibody–Drug Conjugates with Different Payloads

Journal of pharmaceutical sciences, 2024-08, Vol.113 (8), p.2443-2453

2024

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Freeze-Dry Microscopy: Impact of Nucleation Temperature and Excipient Concentration on Collapse Temperature Data

AAPS PharmSciTech, 2009, Vol.10 (2), p.582-588

2009

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Freeze-Drying From Organic Co-Solvent Systems, Part 2: Process Modifications to Reduce Residual Solvent Levels and Improve Product Quality Attributes

Journal of pharmaceutical sciences, 2019-01, Vol.108 (1), p.399-415

2019

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Freeze-Drying From Organic Cosolvent Systems, Part 1: Thermal Analysis of Cosolvent-Based Placebo Formulations in the Frozen State

Journal of pharmaceutical sciences, 2018-03, Vol.107 (3), p.887-896

2018

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Heat Transfer Characteristics of Current Primary Packaging Systems for Pharmaceutical Freeze-Drying

Journal of pharmaceutical sciences, 2012-11, Vol.101 (11), p.4025-4031

2012

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Miniaturized Forced Degradation of Therapeutic Proteins and ADCs by Agitation-Induced Aggregation Using Orbital Shaking of Microplates

Journal of pharmaceutical sciences, 2022-05, Vol.111 (5), p.1401-1413

2022

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Alteration of Physicochemical Properties for Antibody-Drug Conjugates and Their Impact on Stability

Journal of pharmaceutical sciences, 2020-01, Vol.109 (1), p.161-168

2020

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Prediction of Protein Aggregation in High Concentration Protein Solutions Utilizing Protein-Protein Interactions Determined by Low Volume Static Light Scattering

Journal of pharmaceutical sciences, 2016-06, Vol.105 (6), p.1819-1828

2016

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Freeze-Dry Microscopy of Protein/Sugar Mixtures: Drying Behavior, Interpretation of Collapse Temperatures and a Comparison to Corresponding Glass Transition Data

Impact of Payload Hydrophobicity on the Stability of Antibody–Drug Conjugates

Freeze Drying of l-Arginine/Sucrose-Based Protein Formulations, Part I: Influence of Formulation and Arginine Counter Ion on the Critical Formulation Temperature, Product Performance and Protein Stability

Freeze-Drying of l-Arginine/Sucrose-Based Protein Formulations, Part 2: Optimization of Formulation Design and Freeze-Drying Process Conditions for an l-Arginine Chloride-Based Protein Formulation System

Evaluation of a New Wireless Temperature Remote Interrogation System (TEMPRIS) to Measure Product Temperature During Freeze Drying

Predictive Screening Tools Used in High-Concentration Protein Formulation Development

Use of manometric temperature measurement (MTM) and SMART™ freeze dryer technology for development of an optimized freeze‐drying cycle

Molded Vial Manufacturing and Its Impact on Heat Transfer during Freeze-Drying: Vial Geometry Considerations

Factors Influencing the Retention of Organic Solvents in Products Freeze-Dried From Co-Solvent Systems

Evaluation of Packaging Materials in Freeze-Drying: Use of Polymer Caps and Nested Vials and Their Impact on Process and Product Attributes

Merits and Limitations of Dynamic Vapor Sorption Studies on the Morphology and Physicochemical State of Freeze-Dried Products

Gravimetric Measurement of Momentary Drying Rate of Spray Freeze-Dried Powders in Vials

Evaluation of tunable diode laser absorption spectroscopy for in‐process water vapor mass flux measurements during freeze drying

Design of Vacuum-Induced Freezing Protocols for High Fill Volume Formulations in Freeze-Drying: A Strategic Approach

Investigation of Two Different Pressure-Based Controlled Ice Nucleation Techniques in Freeze-Drying: The Integral Role of Shelf Temperature After Nucleation in Process Performance and Product Quality

Agitation-Induced Aggregation of Lysine- And Interchain Cysteine-Linked Antibody-Drug Conjugates

“Negative” Impact: The Role of Payload Charge in the Physicochemical Stability of Auristatin Antibody–Drug Conjugates

Evaluating the Potential of Cyclodextrins in Reducing Aggregation of Antibody–Drug Conjugates with Different Payloads

Freeze-Dry Microscopy: Impact of Nucleation Temperature and Excipient Concentration on Collapse Temperature Data

Freeze-Drying From Organic Co-Solvent Systems, Part 2: Process Modifications to Reduce Residual Solvent Levels and Improve Product Quality Attributes

Freeze-Drying From Organic Cosolvent Systems, Part 1: Thermal Analysis of Cosolvent-Based Placebo Formulations in the Frozen State

Heat Transfer Characteristics of Current Primary Packaging Systems for Pharmaceutical Freeze-Drying

Miniaturized Forced Degradation of Therapeutic Proteins and ADCs by Agitation-Induced Aggregation Using Orbital Shaking of Microplates

Alteration of Physicochemical Properties for Antibody-Drug Conjugates and Their Impact on Stability

Prediction of Protein Aggregation in High Concentration Protein Solutions Utilizing Protein-Protein Interactions Determined by Low Volume Static Light Scattering

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