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Ferroptosis and autophagy induced cell death occur independently after siramesine and lapatinib treatment in breast cancer cells

PloS one, 2017-08, Vol.12 (8), p.e0182921-e0182921

2017

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Starvation-induced autophagy is regulated by mitochondrial reactive oxygen species leading to AMPK activation

Cellular signalling, 2013-01, Vol.25 (1), p.50-65

2013

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Regulation of autophagy by reactive oxygen species (ROS): implications for cancer progression and treatment

Antioxidants & redox signaling, 2009-04, Vol.11 (4), p.777

2009

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A matter of balance between life and death: Targeting reactive oxygen species (ROS)-induced autophagy for cancer therapy

Autophagy, 2010-10, Vol.6 (7), p.835-837

Gibson, Spencer B.

2010

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Lysosomes as Oxidative Targets for Cancer Therapy

Oxidative medicine and cellular longevity, 2017-01, Vol.2017 (1), p.3749157-3749157

2017

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Is mitochondrial generation of reactive oxygen species a trigger for autophagy?

Autophagy, 2008-02, Vol.4 (2), p.246-248

2008

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Negative regulators of cell death pathways in cancer: perspective on biomarkers and targeted therapies

Apoptosis (London), 2018-02, Vol.23 (2), p.93-112

2018

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Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species

Journal of cell science, 2007-12, Vol.120 (23), p.4155-4166

2007

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Surviving cell death through epidermal growth factor (EGF) signal transduction pathways: Implications for cancer therapy

Cellular signalling, 2006-12, Vol.18 (12), p.2089-2097

2006

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Lysosomal Destabilizing Drug Siramesine and the Dual Tyrosine Kinase Inhibitor Lapatinib Induce a Synergistic Ferroptosis through Reduced Heme Oxygenase-1 (HO-1) Levels

Oxidative medicine and cellular longevity, 2019, Vol.2019, p.9561281-14

2019

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Tyrosine kinase receptor EGFR regulates the switch in cancer cells between cell survival and cell death induced by autophagy in hypoxia

Autophagy, 2016-06, Vol.12 (6), p.1029-1046

2016

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On-target effect of FK866, a nicotinamide phosphoribosyl transferase inhibitor, by apoptosis-mediated death in chronic lymphocytic leukemia cells

Clinical cancer research, 2014-09, Vol.20 (18), p.4861-4872

2014

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Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3

Autophagy, 2008-02, Vol.4 (2), p.195-204

2008

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Prostate Cancer Cells Are Sensitive to Lysosomotropic Agent Siramesine through Generation Reactive Oxygen Species and in Combination with Tyrosine Kinase Inhibitors

Cancers, 2022-11, Vol.14 (22), p.5478

2022

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Reactive Oxygen Species (ROS) Regulates Different Types of Cell Death by Acting as a Rheostat

Oxidative medicine and cellular longevity, 2021, Vol.2021, p.9912436-17

2021

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The BH3 only Bcl-2 family member BNIP3 regulates cellular proliferation

PloS one, 2018-10, Vol.13 (10), p.e0204792-e0204792

2018

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Tumor Suppressing Subtransferable Candidate 4 Expression Prevents Autophagy-Induced Cell Death Following Temozolomide Treatment in Glioblastoma Cells

Frontiers in cell and developmental biology, 2022-03, Vol.10, p.823251-823251

2022

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Real world risk of infusion reactions and effectiveness of front-line obinutuzumab plus chlorambucil compared with other frontline treatments for chronic lymphocytic leukemia

BMC cancer, 2022-02, Vol.22 (1), p.148-148, Article 148

2022

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Estrogen regulation of anti-apoptotic Bcl-2 family member Mcl-1 expression in breast cancer cells

PloS one, 2014-06, Vol.9 (6), p.e100364

2014

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Erb-b2 Receptor Tyrosine Kinase 2 (ERBB2) Promotes ATG12-Dependent Autophagy Contributing to Treatment Resistance of Breast Cancer Cells

Cancers, 2021-03, Vol.13 (5), p.1038

2021

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Lysosome-Disrupting Agents in Combination with Venetoclax Increase Apoptotic Response in Primary Chronic Lymphocytic Leukemia (CLL) Cells Mediated by Lysosomal Cathepsin D Release and Inhibition of Autophagy

Cells (Basel, Switzerland), 2024-06, Vol.13 (12), p.1041

2024

Volltextzugriff (PDF)

Altered T Follicular Helper Cell Subsets and Function in Chronic Lymphocytic Leukemia

Frontiers in oncology, 2021-04, Vol.11, p.674492-674492

2021

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Three dimensions of autophagy in regulating tumor growth: cell survival/death, cell proliferation, and tumor dormancy

Biochimica et biophysica acta. Molecular basis of disease, 2021-12, Vol.1867 (12), p.166265-166265, Article 166265

2021

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Reactive oxygen species regulation of autophagy in cancer: Implications for cancer treatment

Free radical biology & medicine, 2012-10, Vol.53 (7), p.1399-1410

2012

Volltextzugriff (PDF)

Cucurbitacin-I (JSI-124) activates the JNK/c-Jun signaling pathway independent of apoptosis and cell cycle arrest in B leukemic cells

BMC cancer, 2011-06, Vol.11 (1), p.268-268, Article 268

2011

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Ferroptosis and autophagy induced cell death occur independently after siramesine and lapatinib treatment in breast cancer cells

Starvation-induced autophagy is regulated by mitochondrial reactive oxygen species leading to AMPK activation

Regulation of autophagy by reactive oxygen species (ROS): implications for cancer progression and treatment

A matter of balance between life and death: Targeting reactive oxygen species (ROS)-induced autophagy for cancer therapy

Lysosomes as Oxidative Targets for Cancer Therapy

Is mitochondrial generation of reactive oxygen species a trigger for autophagy?

Negative regulators of cell death pathways in cancer: perspective on biomarkers and targeted therapies

Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species

Surviving cell death through epidermal growth factor (EGF) signal transduction pathways: Implications for cancer therapy

Lysosomal Destabilizing Drug Siramesine and the Dual Tyrosine Kinase Inhibitor Lapatinib Induce a Synergistic Ferroptosis through Reduced Heme Oxygenase-1 (HO-1) Levels

Tyrosine kinase receptor EGFR regulates the switch in cancer cells between cell survival and cell death induced by autophagy in hypoxia

On-target effect of FK866, a nicotinamide phosphoribosyl transferase inhibitor, by apoptosis-mediated death in chronic lymphocytic leukemia cells

Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3

Prostate Cancer Cells Are Sensitive to Lysosomotropic Agent Siramesine through Generation Reactive Oxygen Species and in Combination with Tyrosine Kinase Inhibitors

Reactive Oxygen Species (ROS) Regulates Different Types of Cell Death by Acting as a Rheostat

The BH3 only Bcl-2 family member BNIP3 regulates cellular proliferation

Tumor Suppressing Subtransferable Candidate 4 Expression Prevents Autophagy-Induced Cell Death Following Temozolomide Treatment in Glioblastoma Cells

Real world risk of infusion reactions and effectiveness of front-line obinutuzumab plus chlorambucil compared with other frontline treatments for chronic lymphocytic leukemia

Estrogen regulation of anti-apoptotic Bcl-2 family member Mcl-1 expression in breast cancer cells

Erb-b2 Receptor Tyrosine Kinase 2 (ERBB2) Promotes ATG12-Dependent Autophagy Contributing to Treatment Resistance of Breast Cancer Cells

Lysosome-Disrupting Agents in Combination with Venetoclax Increase Apoptotic Response in Primary Chronic Lymphocytic Leukemia (CLL) Cells Mediated by Lysosomal Cathepsin D Release and Inhibition of Autophagy

Altered T Follicular Helper Cell Subsets and Function in Chronic Lymphocytic Leukemia

Three dimensions of autophagy in regulating tumor growth: cell survival/death, cell proliferation, and tumor dormancy

Reactive oxygen species regulation of autophagy in cancer: Implications for cancer treatment

Cucurbitacin-I (JSI-124) activates the JNK/c-Jun signaling pathway independent of apoptosis and cell cycle arrest in B leukemic cells

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