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The evolution of plasma cholesterol: Direct utility or a “spandrel” of hepatic lipid metabolism?

Progress in lipid research, 2009-03, Vol.48 (2), p.73-91

2009

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Plasma Free Fatty Acids and Peroxisome Proliferator–Activated Receptor α in the Control of Myocardial Uncoupling Protein Levels

Diabetes (New York, N.Y.), 2005-12, Vol.54 (12), p.3496-3502

2005

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Transcript and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis

The FASEB journal, 2005-07, Vol.19 (9), p.1108-1119

2005

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The role of cytochrome P450 in the regulation of cholesterol biosynthesis

Lipids, 2002-12, Vol.37 (12), p.1163-1170

Gibbons, Geoffrey F.

2002

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Inhibition of cholesterol absorption associated with a PPARα-dependent increase in ABC binding cassette transporter A1 in mice

Journal of lipid research, 2003-11, Vol.44 (11), p.2049-2058

2003

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A role for PPARα in the control of SREBP activity and lipid synthesis in the liver

Biochemical journal, 2005-07, Vol.389 (2), p.413-421

2005

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Peroxisome Proliferator-activated Receptor α Deficiency Abolishes the Response of Lipogenic Gene Expression to Re-feeding: RESTORATION OF THE NORMAL RESPONSE BY ACTIVATION OF LIVER X RECEPTOR α

The Journal of biological chemistry, 2008-02, Vol.283 (8), p.4866-4876

2008

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Mobilisation of triacylglycerol stores

BBA - Molecular and Cell Biology of Lipids, 2000-01, Vol.1483 (1), p.37-57

2000

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PPAR-alpha activation required for decreased glucose uptake and increased susceptibility to injury during ischemia

American journal of physiology. Heart and circulatory physiology, 2005-06, Vol.288 (6), p.H2677-H2683

2005

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Regulation of fatty acid and cholesterol synthesis: co-operation or competition?

Progress in Lipid Research, 2003-11, Vol.42 (6), p.479-497

Gibbons, Geoffrey F

2003

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Peroxisome-proliferator-activated receptor-alpha (PPARalpha) deficiency leads to dysregulation of hepatic lipid and carbohydrate metabolism by fatty acids and insulin

Biochemical journal, 2002-06, Vol.364 (Pt 2), p.361-368

2002

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Disturbances in the normal regulation of SREBP-sensitive genes in PPAR alpha-deficient mice

Journal of lipid research, 2001-03, Vol.42 (3), p.328-337

2001

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Effect of dietary fish oil on the sensitivity of hepatic lipid metabolism to regulation by insulin

Journal of lipid research, 2000-05, Vol.41 (5), p.719-726

2000

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Microsomal membrane-associated apoB is the direct precursor of secreted VLDL in primary cultures of rat hepatocytes

Journal of lipid research, 2001-10, Vol.42 (10), p.1609-1617

2001

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Co-ordination of hepatic and adipose tissue lipid metabolism after oral glucose

Journal of lipid research, 1999-11, Vol.40 (11), p.2034-2043

1999

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Insulin inhibits the maturation phase of VLDL assembly via a phosphoinositide 3-kinase-mediated event

Arteriosclerosis, thrombosis, and vascular biology, 2001-10, Vol.21 (10), p.1656-1661

2001

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Glucose phosphorylation is essential for the turnover of neutral lipid and the second stage assembly of triacylglycerol-rich ApoB-containing lipoproteins in primary hepatocyte cultures

Arteriosclerosis, thrombosis, and vascular biology, 1999-02, Vol.19 (2), p.321-329

1999

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Suppression of cytosolic triacylglycerol recruitment for very low density lipoprotein assembly by inactivation of microsomal triglyceride transfer protein results in a delayed removal of apoB-48 and apoB-100 from microsomal and Golgi membranes of primary rat hepatocytes

Journal of lipid research, 1999-10, Vol.40 (10), p.1758-1768

1999

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Up-regulation of pyruvate dehydrogenase kinase isoform 4 (PDK4) protein expression in oxidative skeletal muscle does not require the obligatory participation of peroxisome-proliferator-activated receptor alpha (PPARalpha)

Biochemical journal, 2002-09, Vol.366 (Pt 3), p.839-846

2002

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Evaluation of the role of peroxisome-proliferator-activated receptor alpha in the regulation of cardiac pyruvate dehydrogenase kinase 4 protein expression in response to starvation, high-fat feeding and hyperthyroidism

Biochemical journal, 2002-06, Vol.364 (Pt 3), p.687-694

2002

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Characterization of the Rodent Genes for Arylacetamide Deacetylase, a Putative Microsomal Lipase, and Evidence for Transcriptional Regulation

The Journal of biological chemistry, 2001-10, Vol.276 (43), p.39522-39532

2001

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From gallstones to genes: Two hundred years of sterol research. A tribute to George J. Schroepfer Jr

Lipids, 2002-12, Vol.37 (12), p.1153-1162

Gibbons, Geoffrey F.

2002

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Inhibition of Hepatocyte Lipogenesis by Nitric Oxide Donor: Could Nitric Oxide Regulate Lipid Synthesis?

IUBMB life, 2004-01, Vol.56 (1), p.35-40

2004

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Inflammatory demyelination could be attributed to nitric oxide inhibition of cytosolic CoA with failed lipogenesis

Journal of neurology, 2005-11, Vol.252 (11), p.1418-1419

2005

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Peroxisome Proliferator-activated Receptor α Deficiency Abolishes the Response of Lipogenic Gene Expression to Re-feeding

The Journal of biological chemistry, 2008-02, Vol.283 (8), p.4866-4876

2008

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The evolution of plasma cholesterol: Direct utility or a “spandrel” of hepatic lipid metabolism?

Plasma Free Fatty Acids and Peroxisome Proliferator–Activated Receptor α in the Control of Myocardial Uncoupling Protein Levels

Transcript and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis

The role of cytochrome P450 in the regulation of cholesterol biosynthesis

Inhibition of cholesterol absorption associated with a PPARα-dependent increase in ABC binding cassette transporter A1 in mice

A role for PPARα in the control of SREBP activity and lipid synthesis in the liver

Peroxisome Proliferator-activated Receptor α Deficiency Abolishes the Response of Lipogenic Gene Expression to Re-feeding: RESTORATION OF THE NORMAL RESPONSE BY ACTIVATION OF LIVER X RECEPTOR α

Mobilisation of triacylglycerol stores

PPAR-alpha activation required for decreased glucose uptake and increased susceptibility to injury during ischemia

Regulation of fatty acid and cholesterol synthesis: co-operation or competition?

Peroxisome-proliferator-activated receptor-alpha (PPARalpha) deficiency leads to dysregulation of hepatic lipid and carbohydrate metabolism by fatty acids and insulin

Disturbances in the normal regulation of SREBP-sensitive genes in PPAR alpha-deficient mice

Effect of dietary fish oil on the sensitivity of hepatic lipid metabolism to regulation by insulin

Microsomal membrane-associated apoB is the direct precursor of secreted VLDL in primary cultures of rat hepatocytes

Co-ordination of hepatic and adipose tissue lipid metabolism after oral glucose

Insulin inhibits the maturation phase of VLDL assembly via a phosphoinositide 3-kinase-mediated event

Glucose phosphorylation is essential for the turnover of neutral lipid and the second stage assembly of triacylglycerol-rich ApoB-containing lipoproteins in primary hepatocyte cultures

Suppression of cytosolic triacylglycerol recruitment for very low density lipoprotein assembly by inactivation of microsomal triglyceride transfer protein results in a delayed removal of apoB-48 and apoB-100 from microsomal and Golgi membranes of primary rat hepatocytes

Up-regulation of pyruvate dehydrogenase kinase isoform 4 (PDK4) protein expression in oxidative skeletal muscle does not require the obligatory participation of peroxisome-proliferator-activated receptor alpha (PPARalpha)

Evaluation of the role of peroxisome-proliferator-activated receptor alpha in the regulation of cardiac pyruvate dehydrogenase kinase 4 protein expression in response to starvation, high-fat feeding and hyperthyroidism

Characterization of the Rodent Genes for Arylacetamide Deacetylase, a Putative Microsomal Lipase, and Evidence for Transcriptional Regulation

From gallstones to genes: Two hundred years of sterol research. A tribute to George J. Schroepfer Jr

Inhibition of Hepatocyte Lipogenesis by Nitric Oxide Donor: Could Nitric Oxide Regulate Lipid Synthesis?

Inflammatory demyelination could be attributed to nitric oxide inhibition of cytosolic CoA with failed lipogenesis

Peroxisome Proliferator-activated Receptor α Deficiency Abolishes the Response of Lipogenic Gene Expression to Re-feeding

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