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Ferroportin deficiency in erythroid cells causes serum iron deficiency and promotes hemolysis due to oxidative stress

Blood, 2018-11, Vol.132 (19), p.2078-2087

2018

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Iron Chaperone Poly rC Binding Protein 1 Protects Mouse Liver From Lipid Peroxidation and Steatosis

Hepatology (Baltimore, Md.), 2021-03, Vol.73 (3), p.1176-1193

2021

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Dysfunction of the heme recycling system in heme oxygenase 1–deficient mice: effects on macrophage viability and tissue iron distribution

Blood, 2010-12, Vol.116 (26), p.6054-6062

2010

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The physiological functions of iron regulatory proteins in iron homeostasis - an update

Frontiers in pharmacology, 2014-06, Vol.5, p.124-124

2014

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Erythrocytic ferroportin reduces intracellular iron accumulation, hemolysis, and malaria risk

Science (American Association for the Advancement of Science), 2018-03, Vol.359 (6383), p.1520-1523

2018

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Iron misregulation and neurodegenerative disease in mouse models that lack iron regulatory proteins

Neurobiology of disease, 2015-09, Vol.81, p.66-75

2015

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Iron chaperones PCBP1 and PCBP2 mediate the metallation of the dinuclear iron enzyme deoxyhypusine hydroxylase

Proceedings of the National Academy of Sciences - PNAS, 2014-06, Vol.111 (22), p.8031-8036

2014

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Deletion of Iron Regulatory Protein 1 Causes Polycythemia and Pulmonary Hypertension in Mice through Translational Derepression of HIF2α

Cell metabolism, 2013-02, Vol.17 (2), p.271-281

2013

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Wild-type macrophages reverse disease in heme oxygenase 1-deficient mice

Blood, 2014-08, Vol.124 (9), p.1522-1530

2014

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Correction: Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia

PLoS biology, 2022-05, Vol.20 (5), p.e3001621-e3001621

2022

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CXCR4 regulates migration of lung alveolar epithelial cells through activation of Rac1 and matrix metalloproteinase-2

American journal of physiology. Lung cellular and molecular physiology, 2012-05, Vol.302 (9), p.L846-L856

2012

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Membrane phospholipid augments cytochrome P4501a enzymatic activity by modulating structural conformation during detoxification of xenobiotics

PloS one, 2013-02, Vol.8 (2), p.e57919

2013

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Posttranslational stability of the heme biosynthetic enzyme ferrochelatase is dependent on iron availability and intact iron-sulfur cluster assembly machinery

Blood, 2010-01, Vol.115 (4), p.860-869

2010

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Insulin-like growth factor-I stimulates differentiation of ATII cells to ATI-like cells through activation of Wnt5a

American journal of physiology. Lung cellular and molecular physiology, 2013-08, Vol.305 (3), p.L222-L228

2013

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Mammalian Tissue Oxygen Levels Modulate Iron-Regulatory Protein Activities in Vivo

Science (American Association for the Advancement of Science), 2004-12, Vol.306 (5704), p.2087-2090

2004

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Iron insufficiency compromises motor neurons and their mitochondrial function in Irp2-null mice

PloS one, 2011-10, Vol.6 (10), p.e25404

2011

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Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis

The EMBO journal, 2004-01, Vol.23 (2), p.386-395

2004

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A heteromeric molecular complex regulates the migration of lung alveolar epithelial cells during wound healing

Scientific reports, 2017-05, Vol.7 (1), p.2155-11, Article 2155

2017

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Tempol-mediated activation of latent iron regulatory protein activity prevents symptoms of neurodegenerative disease in IRP2 knockout mice

Proceedings of the National Academy of Sciences - PNAS, 2008-08, Vol.105 (33), p.12028-12033

2008

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Hyperactivation of mTOR and AKT in a cardiac hypertrophy animal model of Friedreich ataxia

Heliyon, 2022-08, Vol.8 (8), p.e10371-e10371, Article e10371

2022

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Absence of iron-responsive element-binding protein 2 causes a novel neurodegenerative syndrome

Brain (London, England : 1878), 2019-05, Vol.142 (5), p.1195-1202

2019

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Involvement of mTOR in CXCL12 mediated T cell signaling and migration

PloS one, 2011-09, Vol.6 (9), p.e24667-e24667

2011

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The iron chaperone poly(rC)-binding protein 1 regulates iron efflux through intestinal ferroportin in mice

Blood, 2023-11, Vol.142 (19), p.1658

2023

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Expression and Functional Characterization of the Cancer-related Serine Protease, Human Tissue Kallikrein 14

The Journal of biological chemistry, 2007-01, Vol.282 (4), p.2405-2422

2007

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Therapeutic inhibition of HIF-2α reverses polycythemia and pulmonary hypertension in murine models of human diseases

Blood, 2021-05, Vol.137 (18), p.2509-2519

2021

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Ferroportin deficiency in erythroid cells causes serum iron deficiency and promotes hemolysis due to oxidative stress

Iron Chaperone Poly rC Binding Protein 1 Protects Mouse Liver From Lipid Peroxidation and Steatosis

Dysfunction of the heme recycling system in heme oxygenase 1–deficient mice: effects on macrophage viability and tissue iron distribution

The physiological functions of iron regulatory proteins in iron homeostasis - an update

Erythrocytic ferroportin reduces intracellular iron accumulation, hemolysis, and malaria risk

Iron misregulation and neurodegenerative disease in mouse models that lack iron regulatory proteins

Iron chaperones PCBP1 and PCBP2 mediate the metallation of the dinuclear iron enzyme deoxyhypusine hydroxylase

Deletion of Iron Regulatory Protein 1 Causes Polycythemia and Pulmonary Hypertension in Mice through Translational Derepression of HIF2α

Wild-type macrophages reverse disease in heme oxygenase 1-deficient mice

Correction: Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia

CXCR4 regulates migration of lung alveolar epithelial cells through activation of Rac1 and matrix metalloproteinase-2

Membrane phospholipid augments cytochrome P4501a enzymatic activity by modulating structural conformation during detoxification of xenobiotics

Posttranslational stability of the heme biosynthetic enzyme ferrochelatase is dependent on iron availability and intact iron-sulfur cluster assembly machinery

Insulin-like growth factor-I stimulates differentiation of ATII cells to ATI-like cells through activation of Wnt5a

Mammalian Tissue Oxygen Levels Modulate Iron-Regulatory Protein Activities in Vivo

Iron insufficiency compromises motor neurons and their mitochondrial function in Irp2-null mice

Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis

A heteromeric molecular complex regulates the migration of lung alveolar epithelial cells during wound healing

Tempol-mediated activation of latent iron regulatory protein activity prevents symptoms of neurodegenerative disease in IRP2 knockout mice

Hyperactivation of mTOR and AKT in a cardiac hypertrophy animal model of Friedreich ataxia

Absence of iron-responsive element-binding protein 2 causes a novel neurodegenerative syndrome

Involvement of mTOR in CXCL12 mediated T cell signaling and migration

The iron chaperone poly(rC)-binding protein 1 regulates iron efflux through intestinal ferroportin in mice

Expression and Functional Characterization of the Cancer-related Serine Protease, Human Tissue Kallikrein 14

Therapeutic inhibition of HIF-2α reverses polycythemia and pulmonary hypertension in murine models of human diseases

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