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Targeting MET in cancer: rationale and progress

Nature reviews. Cancer, 2012-02, Vol.12 (2), p.89-103

2012

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Inhibition of the MET Kinase Activity and Cell Growth in MET-Addicted Cancer Cells by Bi-Paratopic Linking

Journal of molecular biology, 2019-05, Vol.431 (10), p.2020-2039

2019

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Human Nonalcoholic Steatohepatitis on a Chip

Hepatology communications, 2021-02, Vol.5 (2), p.217-233

2021

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A Novel HGF/SF Receptor (MET) Agonist Transiently Delays the Disease Progression in an Amyotrophic Lateral Sclerosis Mouse Model by Promoting Neuronal Survival and Dampening the Immune Dysregulation

International journal of molecular sciences, 2020-11, Vol.21 (22), p.8542

2020

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Structural basis for agonism and antagonism of hepatocyte growth factor

Proceedings of the National Academy of Sciences - PNAS, 2010-07, Vol.107 (30), p.13264-13269

2010

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Structural Basis of Hepatocyte Growth Factor/Scatter Factor and MET Signalling

Proceedings of the National Academy of Sciences - PNAS, 2006-03, Vol.103 (11), p.4046-4051

2006

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Developing Antagonists for the Met-HGF/SF Protein-Protein Interaction Using a Fragment-Based Approach

Molecular cancer therapeutics, 2016-01, Vol.15 (1), p.3-14

2016

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Interactions of Hepatocyte Growth Factor/Scatter Factor with Various Glycosaminoglycans Reveal an Important Interplay between the Presence of Iduronate and Sulfate Density

The Journal of biological chemistry, 2008-02, Vol.283 (9), p.5235-5248

2008

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Characterization and structural determination of a new anti-MET function-blocking antibody with binding epitope distinct from the ligand binding domain

Scientific reports, 2017-08, Vol.7 (1), p.9000-13, Article 9000

2017

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Diverse and potent activities of HGF/SF in skin wound repair

The Journal of pathology, 2004-07, Vol.203 (3), p.831-838

2004

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Protein Engineered Variants of Hepatocyte Growth Factor/Scatter Factor Promote Proliferation of Primary Human Hepatocytes and in Rodent Liver

Gastroenterology (New York, N.Y. 1943), 2012-04, Vol.142 (4), p.897-906

2012

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Non-agonistic bivalent antibodies that promote c-MET degradation and inhibit tumor growth and others specific for tumor related c-MET

PloS one, 2012-04, Vol.7 (4), p.e34658-e34658

2012

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Functional Map and Domain Structure of MET, the Product of the c-met Protooncogene and Receptor for Hepatocyte Growth Factor/Scatter Factor

Proceedings of the National Academy of Sciences - PNAS, 2003-10, Vol.100 (21), p.12039-12044

2003

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Scatter factor/hepatocyte growth factor is essential for liver development

Nature (London), 1995-02, Vol.373 (6516), p.699-702

1995

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Engineering the NK1 Fragment of Hepatocyte Growth Factor/Scatter Factor as a MET Receptor Antagonist

Journal of molecular biology, 2008-03, Vol.377 (3), p.616-622

2008

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mechanistic basis for converting a receptor tyrosine kinase agonist to an antagonist

Proceedings of the National Academy of Sciences - PNAS, 2007-09, Vol.104 (37), p.14592-14597

2007

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Coupling growth-factor engineering with nanotechnology for therapeutic angiogenesis

Proceedings of the National Academy of Sciences - PNAS, 2010-08, Vol.107 (31), p.13608-13613

2010

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Hepatocyte growth factor/scatter factor can induce angiogenesis independently of vascular endothelial growth factor

Arteriosclerosis, thrombosis, and vascular biology, 2003-01, Vol.23 (1), p.69-75

2003

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X-ray and Neutron Small-Angle Scattering Analysis of the Complex Formed by the Met Receptor and the Listeria monocytogenes Invasion Protein InlB

Journal of molecular biology, 2008-03, Vol.377 (2), p.489-500

2008

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Hepatocyte Growth Factor/Scatter Factor and MET Are Involved in Arterial Repair and Atherogenesis

The American journal of pathology, 2006, Vol.168 (1), p.340-348

2006

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Computer‐assisted mass spectrometric analysis of naturally occurring and artificially introduced cross‐links in proteins and protein complexes

The FEBS journal, 2006-01, Vol.273 (2), p.281-291

2006

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Eotaxin-1/CC Chemokine Ligand 11: A Novel Eosinophil Survival Factor Secreted by Human Pulmonary Artery Endothelial Cells

Journal of Immunology, 2007-07, Vol.179 (2), p.1264-1273

2007

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Heparan Sulfate-modified CD44 Promotes Hepatocyte Growth Factor/Scatter Factor-induced Signal Transduction through the Receptor Tyrosine Kinase c-Met

The Journal of biological chemistry, 1999-03, Vol.274 (10), p.6499-6506

1999

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Involvement of hepatocyte growth factor/scatter factor and Met receptor signaling in hair follicle morphogenesis and cycling

The FASEB journal, 2000-02, Vol.14 (2), p.319-332

2000

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Met, metastasis, motility and more

Nature reviews. Molecular cell biology, 2003-12, Vol.4 (12), p.915-925

2003

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Targeting MET in cancer: rationale and progress

Inhibition of the MET Kinase Activity and Cell Growth in MET-Addicted Cancer Cells by Bi-Paratopic Linking

Human Nonalcoholic Steatohepatitis on a Chip

A Novel HGF/SF Receptor (MET) Agonist Transiently Delays the Disease Progression in an Amyotrophic Lateral Sclerosis Mouse Model by Promoting Neuronal Survival and Dampening the Immune Dysregulation

Structural basis for agonism and antagonism of hepatocyte growth factor

Structural Basis of Hepatocyte Growth Factor/Scatter Factor and MET Signalling

Developing Antagonists for the Met-HGF/SF Protein-Protein Interaction Using a Fragment-Based Approach

Interactions of Hepatocyte Growth Factor/Scatter Factor with Various Glycosaminoglycans Reveal an Important Interplay between the Presence of Iduronate and Sulfate Density

Characterization and structural determination of a new anti-MET function-blocking antibody with binding epitope distinct from the ligand binding domain

Diverse and potent activities of HGF/SF in skin wound repair

Protein Engineered Variants of Hepatocyte Growth Factor/Scatter Factor Promote Proliferation of Primary Human Hepatocytes and in Rodent Liver

Non-agonistic bivalent antibodies that promote c-MET degradation and inhibit tumor growth and others specific for tumor related c-MET

Functional Map and Domain Structure of MET, the Product of the c-met Protooncogene and Receptor for Hepatocyte Growth Factor/Scatter Factor

Scatter factor/hepatocyte growth factor is essential for liver development

Engineering the NK1 Fragment of Hepatocyte Growth Factor/Scatter Factor as a MET Receptor Antagonist

mechanistic basis for converting a receptor tyrosine kinase agonist to an antagonist

Coupling growth-factor engineering with nanotechnology for therapeutic angiogenesis

Hepatocyte growth factor/scatter factor can induce angiogenesis independently of vascular endothelial growth factor

X-ray and Neutron Small-Angle Scattering Analysis of the Complex Formed by the Met Receptor and the Listeria monocytogenes Invasion Protein InlB

Hepatocyte Growth Factor/Scatter Factor and MET Are Involved in Arterial Repair and Atherogenesis

Computer‐assisted mass spectrometric analysis of naturally occurring and artificially introduced cross‐links in proteins and protein complexes

Eotaxin-1/CC Chemokine Ligand 11: A Novel Eosinophil Survival Factor Secreted by Human Pulmonary Artery Endothelial Cells

Heparan Sulfate-modified CD44 Promotes Hepatocyte Growth Factor/Scatter Factor-induced Signal Transduction through the Receptor Tyrosine Kinase c-Met

Involvement of hepatocyte growth factor/scatter factor and Met receptor signaling in hair follicle morphogenesis and cycling

Met, metastasis, motility and more

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