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Cutting Edge: DNase II deficiency prevents activation of autoreactive B cells by double-stranded DNA endogenous ligands

The Journal of immunology (1950), 2015-02, Vol.194 (4), p.1403-1407

2015

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Simultaneous targeting of multiple disease mediators by a dual-variable-domain immunoglobulin

Nature biotechnology, 2007-11, Vol.25 (11), p.1290-1297

2007

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CRISPR/Cas9-targeting of CD40 in hematopoietic stem cells limits immune activation mediated by anti-CD40

PloS one, 2020-03, Vol.15 (3), p.e0228221-e0228221

2020

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Identification of Anti-EGFR and Anti-ErbB3 Dual Variable Domains Immunoglobulin (DVD-Ig) Proteins with Unique Activities

PloS one, 2015-05, Vol.10 (5), p.e0124135-e0124135

2015

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Structure reveals function of the dual variable domain immunoglobulin (DVD-Ig™) molecule

mAbs, 2013-05, Vol.5 (3), p.358-363

2013

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Molecular construction and optimization of anti-human IL-1α/β dual variable domain immunoglobulin (DVD-IgTM) molecules

mAbs, 2009-08, Vol.1 (4), p.339-347

2009

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Identification of anti-ErbB2 dual variable domain immunoglobulin (DVD-Ig™) proteins with unique activities

PloS one, 2014-05, Vol.9 (5), p.e97292

2014

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Substrate Specificities of Caspase Family Proteases

The Journal of biological chemistry, 1997-04, Vol.272 (15), p.9677-9682

1997

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Potent and conditional redirected T cell killing of tumor cells using Half DVD-Ig

Protein & cell, 2018-01, Vol.9 (1), p.121-129

2018

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Unusual Water-mediated Antigenic Recognition of the Proinflammatory Cytokine Interleukin-18

The Journal of biological chemistry, 2009-09, Vol.284 (36), p.24478-24489

2009

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Generation of Dual-Variable-Domain Immunoglobulin Molecules for Dual-Specific Targeting

Methods in Enzymology, 2012, Vol.502, p.25-41

2012

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Recent advancements in DVD-Ig based therapeutic development

Drug discovery today. Technologies, 2019-12, Vol.34, p.1-7

2019

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Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35

Science (American Association for the Advancement of Science), 1995-09, Vol.269 (5232), p.1885-1888

1995

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Ligand association rates to the inner-variable-domain of a dual-variable-domain immunoglobulin are significantly impacted by linker design

mAbs, 2011-09, Vol.3 (5), p.487-494

2011

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Generation of Anti-apoptotic Presenilin-2 Polypeptides by Alternative Transcription, Proteolysis, and Caspase-3 Cleavage

The Journal of biological chemistry, 1997-11, Vol.272 (45), p.28315-28320

1997

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Targeting dendritic cell inhibitory receptors to down regulate immune response in inflammatory disease

The Journal of immunology (1950), 2023-05, Vol.210 (1_Supplement), p.146-146.01

2023

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Regulation of Protein Phosphatase 2A Activity by Caspase-3 during Apoptosis

The Journal of biological chemistry, 1998-05, Vol.273 (21), p.13119-13128

1998

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Proteolytic cleavage of phospholipase C–γ1 during apoptosis in Molt–4 cells

The FASEB journal, 2000-06, Vol.14 (9), p.1083-1092

2000

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Brain uptake of multivalent and multi-specific DVD-Ig proteins after systemic administration

mAbs, 2018-07, Vol.10 (5), p.765-777

2018

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Transmembrane TNF-dependent uptake of anti-TNF antibodies

mAbs, 2017-05, Vol.9 (4), p.680-695

2017

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Human natural killer cells: a unique innate immunoregulatory role for the CD56(bright) subset

Blood, 2001-05, Vol.97 (10), p.3146

2001

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Su1044 – Optimization of Culture Conditions for Improved Growth and Functional Differentiation of Colon Organoids

Gastroenterology (New York, N.Y. 1943), 2019-05, Vol.156 (6), p.S-493-S-493

2019

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DNase II-deficiency Prevents Activation of Autoreactive B cells by dsDNA Endogenous Ligands

The Journal of immunology (1950), 2015-01, Vol.194 (4), p.1403-1407

2015

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The structure of dual-variable-domain immunoglobulin molecules alone and bound to antigen

mAbs, 2013-05, Vol.5 (3), p.364-372

2013

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Expression and alternative processing of IL‐18 inhuman neutrophils

European journal of immunology, 2006-03, Vol.36 (3), p.722-731

2006

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Cutting Edge: DNase II deficiency prevents activation of autoreactive B cells by double-stranded DNA endogenous ligands

Simultaneous targeting of multiple disease mediators by a dual-variable-domain immunoglobulin

CRISPR/Cas9-targeting of CD40 in hematopoietic stem cells limits immune activation mediated by anti-CD40

Identification of Anti-EGFR and Anti-ErbB3 Dual Variable Domains Immunoglobulin (DVD-Ig) Proteins with Unique Activities

Structure reveals function of the dual variable domain immunoglobulin (DVD-Ig™) molecule

Molecular construction and optimization of anti-human IL-1α/β dual variable domain immunoglobulin (DVD-IgTM) molecules

Identification of anti-ErbB2 dual variable domain immunoglobulin (DVD-Ig™) proteins with unique activities

Substrate Specificities of Caspase Family Proteases

Potent and conditional redirected T cell killing of tumor cells using Half DVD-Ig

Unusual Water-mediated Antigenic Recognition of the Proinflammatory Cytokine Interleukin-18

Generation of Dual-Variable-Domain Immunoglobulin Molecules for Dual-Specific Targeting

Recent advancements in DVD-Ig based therapeutic development

Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35

Ligand association rates to the inner-variable-domain of a dual-variable-domain immunoglobulin are significantly impacted by linker design

Generation of Anti-apoptotic Presenilin-2 Polypeptides by Alternative Transcription, Proteolysis, and Caspase-3 Cleavage

Targeting dendritic cell inhibitory receptors to down regulate immune response in inflammatory disease

Regulation of Protein Phosphatase 2A Activity by Caspase-3 during Apoptosis

Proteolytic cleavage of phospholipase C–γ1 during apoptosis in Molt–4 cells

Brain uptake of multivalent and multi-specific DVD-Ig proteins after systemic administration

Transmembrane TNF-dependent uptake of anti-TNF antibodies

Human natural killer cells: a unique innate immunoregulatory role for the CD56(bright) subset

Su1044 – Optimization of Culture Conditions for Improved Growth and Functional Differentiation of Colon Organoids

DNase II-deficiency Prevents Activation of Autoreactive B cells by dsDNA Endogenous Ligands

The structure of dual-variable-domain immunoglobulin molecules alone and bound to antigen

Expression and alternative processing of IL‐18 inhuman neutrophils

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