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Ortho-Substituted Benzofused Macrocyclic Lactams as Zinc Metalloprotease Inhibitors

Journal of medicinal chemistry, 1997-02, Vol.40 (4), p.495-505

1997

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N-Phosphonomethyl Dipeptides and Their Phosphonate Prodrugs, a New Generation of Neutral Endopeptidase (NEP, EC 3.4.24.11) Inhibitors

Journal of medicinal chemistry, 1994-02, Vol.37 (4), p.498-511

1994

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Dicarboxylic Acid Dipeptide Neutral Endopeptidase Inhibitors

Journal of medicinal chemistry, 1995-05, Vol.38 (10), p.1689-1700

1995

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Identification of protease 3.4.24.11 as the major atrial natriuretic factor degrading enzyme in the rat kidney

Peptides (New York, N.Y. : 1980), 1988, Vol.9 (1), p.173-180

1988

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Degradation of atrial natriuretic factor by kidney cortex membranes. Isolation and characterization of the primary proteolytic product

The Journal of biological chemistry, 1987-08, Vol.262 (24), p.11623-11627

1987

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Meta-Substituted Benzofused Macrocyclic Lactams as Zinc Metalloprotease Inhibitors

Journal of medicinal chemistry, 1997-02, Vol.40 (4), p.506-514

1997

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New .alpha.-Thiol Dipeptide Dual Inhibitors of Angiotensin-I-Converting Enzyme and Neutral Endopeptidase EC 3.4.24.11

Journal of medicinal chemistry, 1995-12, Vol.38 (26), p.5023-5030

1995

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Heterocyclic lactam derivatives as dual angiotensin converting enzyme and neutral endopeptidase 24.11 inhibitors

Journal of medicinal chemistry, 1993-11, Vol.36 (24), p.3829-3833

1993

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Design and synthesis of an orally active macrocyclic neutral endopeptidase 24.11 inhibitor

Journal of medicinal chemistry, 1993-11, Vol.36 (24), p.3821-3828

1993

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Dopaminergic mediation of the diuretic and natriuretic effects of ANF in the rat

Life sciences (1973), 1986-06, Vol.38 (25), p.2319-2327

1986

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EFFECTS OF A NEUTRAL ENDOPROTEASE ENZYME INHIBITOR, THIORPHAN, ON HEMODYNAMICS AND RENAL EXCRETORY FUNCTION IN FOUR MODELS OF EXPERIMENTAL HYPERTENSION

Clinical and experimental hypertension (1993), 2000, Vol.22 (1), p.45-62

2000

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Structure and location of the O-glycosidic carbohydrate units of human chorionic gonadotropin

The Journal of biological chemistry, 1979-08, Vol.254 (16), p.7909-7914

1979

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Pharmacologic Profile of CGS 24128, a Potent, Long-Acting Inhibitor of Neutral Endopeptidase 24.11

Journal of cardiovascular pharmacology, 1994-03, Vol.23 (3), p.358-364

1994

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Enkephalinase inhibitors. 1. 2,4-Dibenzylglutaric acid derivatives

Journal of medicinal chemistry, 1989-12, Vol.32 (12), p.2519-2526

1989

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Biochemical and immunocytochemical analysis of a histone H1 variant from the mouse testis

Journal of cell science, 1989-09, Vol.94 (1), p.61-71

1989

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Occurrence of neutral endopeptidase activity in the cat carotid body and its significance in chemoreception

Brain research, 1990-05, Vol.517 (1), p.341-343

1990

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Role of atrial natriuretic factor in regulation of blood pressure in normotensive rats having reduced renal mass

Experimental biology and medicine (Maywood, N.J.), 1988-12, Vol.189 (3), p.297-303

1988

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Biochemical and immunological characterization of a histone variant associated with spermatogenesis in the mouse

Biochimica et biophysica acta, 1983-10, Vol.760 (1), p.25-33

1983

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The Biological Activity of Atrial Natriuretic Factor Cleaved by Endoprotease 3.4.24.11

Journal of enzyme inhibition, 1991, Vol.4 (3), p.267-272

1991

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Antihypertensive and natriuretic effects of CGS 30440, a dual inhibitor of angiotensin-converting enzyme and neutral endopeptidase 24.11

The Journal of pharmacology and experimental therapeutics, 1998-03, Vol.284 (3), p.974

1998

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Atrial natriuretic factor: Atrial conversion of high to low molecular weight forms

Biochemical and biophysical research communications, 1984-01, Vol.119 (1), p.282-288

1984

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Disposition of thiorphan in DOCA-salt and spontaneously hypertensive rats

Research communications in chemical pathology and pharmacology, 1993-08, Vol.81 (2), p.151

1993

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Immunological properties of the β-subunit of human chorionic gonadotropin

Biochemical and biophysical research communications, 1976-05, Vol.70 (2), p.525-532

1976

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Pharmacological Profile of a Non-peptidic Dual Inhibitor of Neutral Endopeptidase 24.11 and Endothelin-Converting Enzyme

Biochemical and biophysical research communications, 1994-10, Vol.204 (1), p.407-412

1994

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A Comparison of the Vasorelaxant and Hemodynamic Properties of Synthetic Atriopeptins

Journal of cardiovascular pharmacology, 1986-11, Vol.8 (6), p.1308-1308

1986

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Ortho-Substituted Benzofused Macrocyclic Lactams as Zinc Metalloprotease Inhibitors

N-Phosphonomethyl Dipeptides and Their Phosphonate Prodrugs, a New Generation of Neutral Endopeptidase (NEP, EC 3.4.24.11) Inhibitors

Dicarboxylic Acid Dipeptide Neutral Endopeptidase Inhibitors

Identification of protease 3.4.24.11 as the major atrial natriuretic factor degrading enzyme in the rat kidney

Degradation of atrial natriuretic factor by kidney cortex membranes. Isolation and characterization of the primary proteolytic product

Meta-Substituted Benzofused Macrocyclic Lactams as Zinc Metalloprotease Inhibitors

New .alpha.-Thiol Dipeptide Dual Inhibitors of Angiotensin-I-Converting Enzyme and Neutral Endopeptidase EC 3.4.24.11

Heterocyclic lactam derivatives as dual angiotensin converting enzyme and neutral endopeptidase 24.11 inhibitors

Design and synthesis of an orally active macrocyclic neutral endopeptidase 24.11 inhibitor

Dopaminergic mediation of the diuretic and natriuretic effects of ANF in the rat

EFFECTS OF A NEUTRAL ENDOPROTEASE ENZYME INHIBITOR, THIORPHAN, ON HEMODYNAMICS AND RENAL EXCRETORY FUNCTION IN FOUR MODELS OF EXPERIMENTAL HYPERTENSION

Structure and location of the O-glycosidic carbohydrate units of human chorionic gonadotropin

Pharmacologic Profile of CGS 24128, a Potent, Long-Acting Inhibitor of Neutral Endopeptidase 24.11

Enkephalinase inhibitors. 1. 2,4-Dibenzylglutaric acid derivatives

Biochemical and immunocytochemical analysis of a histone H1 variant from the mouse testis

Occurrence of neutral endopeptidase activity in the cat carotid body and its significance in chemoreception

Role of atrial natriuretic factor in regulation of blood pressure in normotensive rats having reduced renal mass

Biochemical and immunological characterization of a histone variant associated with spermatogenesis in the mouse

The Biological Activity of Atrial Natriuretic Factor Cleaved by Endoprotease 3.4.24.11

Antihypertensive and natriuretic effects of CGS 30440, a dual inhibitor of angiotensin-converting enzyme and neutral endopeptidase 24.11

Atrial natriuretic factor: Atrial conversion of high to low molecular weight forms

Disposition of thiorphan in DOCA-salt and spontaneously hypertensive rats

Immunological properties of the β-subunit of human chorionic gonadotropin

Pharmacological Profile of a Non-peptidic Dual Inhibitor of Neutral Endopeptidase 24.11 and Endothelin-Converting Enzyme

A Comparison of the Vasorelaxant and Hemodynamic Properties of Synthetic Atriopeptins

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