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The c-myb proto-oncogene and microRNA-15a comprise an active autoregulatory feedback loop in human hematopoietic cells

Blood, 2009-01, Vol.113 (3), p.505-516

2009

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Embryonic and adult stem cell therapy

Journal of allergy and clinical immunology, 2010-02, Vol.125 (2), p.S336-S344

2010

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c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis

The Journal of clinical investigation, 2010-02, Vol.120 (2), p.593-606

2010

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Short interfering RNA (siRNA) targeting the Lyn kinase induces apoptosis in primary, and drug-resistant, BCR-ABL1(+) leukemia cells

Nature medicine, 2004-11, Vol.10 (11), p.1187-1189

2004

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Synergistic effects between analogs of DNA and RNA improve the potency of siRNA-mediated gene silencing

Nucleic acids research, 2010-07, Vol.38 (13), p.4547-4557

2010

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Numerous growth factors, cytokines, and chemokines are secreted by human CD34+ cells, myeloblasts, erythroblasts, and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine manner

Blood, 2001-05, Vol.97 (10), p.3075-3085

2001

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Mechanism of and requirement for estrogen-regulated MYB expression in estrogen-receptor-positive breast cancer cells

Proceedings of the National Academy of Sciences - PNAS, 2007-08, Vol.104 (34), p.13762-13767

2007

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c-Myb and GATA-3 cooperatively regulate IL-13 expression via conserved GATA-3 response element and recruit mixed lineage leukemia (MLL) for histone modification of the IL-13 locus

The Journal of immunology (1950), 2011-12, Vol.187 (11), p.5974-5982

2011

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A Phase I Study of the Mammalian Target of Rapamycin Inhibitor Sirolimus and MEC Chemotherapy in Relapsed and Refractory Acute Myelogenous Leukemia

Clinical cancer research, 2009-11, Vol.15 (21), p.6732-6739

2009

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A prototype nonpeptidyl, hydrazone class, thrombopoietin receptor agonist, SB-559457, is toxic to primary human myeloid leukemia cells

Blood, 2010-01, Vol.115 (1), p.89-93

2010

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c-Myb Contributes to G2/M Cell Cycle Transition in Human Hematopoietic Cells by Direct Regulation of Cyclin B1 Expression

Molecular and Cellular Biology, 2007-03, Vol.27 (6), p.2048-2058

2007

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Phenylpyrrolocytosine as an Unobtrusive Base Modification for Monitoring Activity and Cellular Trafficking of siRNA

ACS chemical biology, 2011-09, Vol.6 (9), p.912-919

2011

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Real time detection of DNA⋅RNA hybridization in living cells

Proceedings of the National Academy of Sciences - PNAS, 1998-09, Vol.95 (20), p.11538-11543

1998

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On future's doorstep: RNA interference and the pharmacopeia of tomorrow

The Journal of clinical investigation, 2007-12, Vol.117 (12), p.3612-3614

Gewirtz, Alan M

2007

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The Histone Acetyltransferase TIP60 Interacts with c-Myb and Inactivates Its Transcriptional Activity in Human Leukemia

The Journal of biological chemistry, 2012-01, Vol.287 (2), p.925-934

2012

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Nucleic-acid therapeutics: basic principles and recent applications

Nature reviews. Drug discovery, 2002-07, Vol.1 (7), p.503-514

2002

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Integrin inhibition through Lyn-dependent cross talk from CXCR4 chemokine receptors in normal human CD34+ marrow cells

Blood, 2006-06, Vol.107 (11), p.4234-4239

2006

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Effects of local mRNA structure on posttranscriptional gene silencing

Proceedings of the National Academy of Sciences - PNAS, 2008-09, Vol.105 (37), p.13787-13792

2008

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Crosstalk between BCR/ABL oncoprotein and CXCR4 signaling through a Src family kinase in human leukemia cells

The Journal of experimental medicine, 2002-09, Vol.196 (5), p.667-678

2002

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Antitumor Efficacy of the Cytotoxic RNase, Ranpirnase, on A549 Human Lung Cancer Xenografts of Nude Mice

Anticancer research, 2007-01, Vol.27 (1A), p.299-307

2007

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Regulating gene expression in human leukemia cells using light-activated oligodeoxynucleotides

Nucleic acids research, 2008-02, Vol.36 (2), p.559-569

2008

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Neuromedin U: a Myb-regulated autocrine growth factor for human myeloid leukemias

Blood, 2004-09, Vol.104 (6), p.1833-1840

2004

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Trisomy 21 enhances human fetal erythro-megakaryocytic development

Blood, 2008-12, Vol.112 (12), p.4503-4506

2008

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Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

Nature genetics, 1999-10, Vol.23 (2), p.166-175

1999

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The c-myb proto-oncogene and microRNA-15a comprise an active autoregulatory feedback loop in human hematopoietic cells

Embryonic and adult stem cell therapy

c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis

Short interfering RNA (siRNA) targeting the Lyn kinase induces apoptosis in primary, and drug-resistant, BCR-ABL1(+) leukemia cells

Synergistic effects between analogs of DNA and RNA improve the potency of siRNA-mediated gene silencing

Numerous growth factors, cytokines, and chemokines are secreted by human CD34+ cells, myeloblasts, erythroblasts, and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine manner

Mechanism of and requirement for estrogen-regulated MYB expression in estrogen-receptor-positive breast cancer cells

c-Myb and GATA-3 cooperatively regulate IL-13 expression via conserved GATA-3 response element and recruit mixed lineage leukemia (MLL) for histone modification of the IL-13 locus

A Phase I Study of the Mammalian Target of Rapamycin Inhibitor Sirolimus and MEC Chemotherapy in Relapsed and Refractory Acute Myelogenous Leukemia

A prototype nonpeptidyl, hydrazone class, thrombopoietin receptor agonist, SB-559457, is toxic to primary human myeloid leukemia cells

c-Myb Contributes to G2/M Cell Cycle Transition in Human Hematopoietic Cells by Direct Regulation of Cyclin B1 Expression

Phenylpyrrolocytosine as an Unobtrusive Base Modification for Monitoring Activity and Cellular Trafficking of siRNA

Real time detection of DNA⋅RNA hybridization in living cells

On future's doorstep: RNA interference and the pharmacopeia of tomorrow

The Histone Acetyltransferase TIP60 Interacts with c-Myb and Inactivates Its Transcriptional Activity in Human Leukemia

Nucleic-acid therapeutics: basic principles and recent applications

Integrin inhibition through Lyn-dependent cross talk from CXCR4 chemokine receptors in normal human CD34+ marrow cells

Effects of local mRNA structure on posttranscriptional gene silencing

Crosstalk between BCR/ABL oncoprotein and CXCR4 signaling through a Src family kinase in human leukemia cells

Antitumor Efficacy of the Cytotoxic RNase, Ranpirnase, on A549 Human Lung Cancer Xenografts of Nude Mice

The C-MYB locus is involved in chromosomal translocation and genomic duplications in human T-cell acute leukemia (T-ALL), the translocation defining a new T-ALL subtype in very young children

Regulating gene expression in human leukemia cells using light-activated oligodeoxynucleotides

Neuromedin U: a Myb-regulated autocrine growth factor for human myeloid leukemias

Trisomy 21 enhances human fetal erythro-megakaryocytic development

Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

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