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Suicide inhibition of canine myocardial cytosolic calcium-independent phospholipase A2. Mechanism-based discrimination between calcium-dependent and -independent phospholipases A2

The Journal of biological chemistry, 1991-04, Vol.266 (11), p.7227-7232

1991

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Kinetic and structural evidence for a sequential ordered Bi Bi mechanism of catalysis by Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase

The Journal of biological chemistry, 1991-05, Vol.266 (15), p.9732-9739

1991

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Discovery of a novel class of potent HIV-1 protease inhibitors containing the (R)-(hydroxyethyl)urea isostere

Journal of medicinal chemistry, 1993, Vol.36 (2), p.288-291

1993

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Design and Synthesis of Novel Imidazole-Substituted Dipeptide Amides as Potent and Selective Inhibitors of Candida albicans MyristoylCoA:Protein N-Myristoyltransferase and Identification of Related Tripeptide Inhibitors with Mechanism-Based Antifungal Activity

Journal of medicinal chemistry, 1997-08, Vol.40 (16), p.2609-2625

1997

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Conformationally Constrained [p-(ω-Aminoalkyl)phenacetyl]-l-seryl-l-lysyl Dipeptide Amides as Potent Peptidomimetic Inhibitors of Candida albicans and Human Myristoyl-CoA:Protein N-Myristoyl Transferase

Journal of medicinal chemistry, 1997-05, Vol.40 (10), p.1422-1438

1997

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Design and Syntheses of Potent and Selective Dipeptide Inhibitors of Candida albicans Myristoyl-CoA:Protein N-Myristoyltransferase

Journal of medicinal chemistry, 1995-05, Vol.38 (11), p.1837-1840

1995

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Discovery of a novel series of selective MMP inhibitors: Identification of the γ-sulfone-thiols

Bioorganic & medicinal chemistry letters, 1999-04, Vol.9 (7), p.943-948

1999

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Structural determinants of haloenol lactone-mediated suicide inhibition of canine myocardial calcium-independent phospholipase A2

Journal of medicinal chemistry, 1993, Vol.36 (1), p.95-100

1993

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α-Amino-β-sulphone hydroxamates as potent MMP-13 inhibitors that spare MMP-1

Bioorganic & medicinal chemistry letters, 2001-10, Vol.11 (20), p.2719-2722

2001

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A Convenient Asymmetric Synthesis of the Unnatural Amino Acid 2,6-Dimethyl-L-tyrosine

Synthesis (Stuttgart), 1992, Vol.1992 (8), p.741-743

1992

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α-Alkyl-α-amino-β-sulphone hydroxamates as potent MMP inhibitors that spare MMP-1

Bioorganic & medicinal chemistry letters, 2001-10, Vol.11 (20), p.2723-2725

2001

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Selective metal-catalyzed autoxidation of 2-arylpropionaldehydes. An improved synthesis of ibuprofen

Journal of organic chemistry, 1987-01, Vol.52 (2), p.287-290

1987

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Selective peptidic and peptidomimetic inhibitors of Candida albicans myristoylCoA: Protein N-myristoyltransferase: A new approach to antifungal therapy

Biopolymers, 1997, Vol.43 (1), p.43-71

1997

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N-myristoylation of Arf proteins in Candida albicans: an in vivo assay for evaluating antifungal inhibitors of myristoyl-CoA: protein N-myristoyltransferase

Microbiology (Society for General Microbiology), 1997-02, Vol.143 ( Pt 2), p.357

1997

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Inhibitors of HIV-1 Protease Containing the Novel and Potent (R)-(Hydroxyethyl)sulfonamide Isostere

Journal of medicinal chemistry, 1995-02, Vol.38 (4), p.581-584

1995

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Synthesis and Structure−Activity Relationships of β- and α-Piperidine Sulfone Hydroxamic Acid Matrix Metalloproteinase Inhibitors with Oral Antitumor Efficacy

Journal of medicinal chemistry, 2005-10, Vol.48 (21), p.6713-6730

2005

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Influence of polyfluorination of the phenylalanine ring of angiotensin II on conformation and biological activity

Biochimica et biophysica acta, 1991-08, Vol.1079 (1), p.23-28

1991

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Discovery of novel benzothiazolesulfonamides as potent inhibitors of HIV-1 protease

Bioorganic & medicinal chemistry, 2003-11, Vol.11 (22), p.4769-4777

2003

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Replacements for lysine in l-seryl- l-lysyl dipeptide amide inhibitors of candida albicans myristoyl-CoA:protein N-myristoyltransferase

Bioorganic & medicinal chemistry letters, 1997-02, Vol.7 (3), p.379-382

1997

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Scanning alanine mutagenesis and de-peptidization of a Candida albicans myristoyl-CoA:protein N-myristoyltransferase octapeptide substrate reveals three elements critical for molecular recognition

The Journal of biological chemistry, 1997-05, Vol.272 (18), p.11874-11880

1997

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Selective functionalization of the C2 hydroxyl group of N-carbobenzyloxy-4,6-Q-benzylidene-1-deoxynojirimycin

Tetrahedron letters, 1991, Vol.32 (41), p.5691-5692

1991

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(Hydroxyethyl) sulfonamide HIV-1 Protease inhibitors: Identification of the 2-methylbenzoyl moiety at P-2

Bioorganic & medicinal chemistry letters, 1996-02, Vol.6 (4), p.445-450

1996

Volltextzugriff (PDF)

Binding of the hydroxyethyl-urea isostere to HIV-1 protease

Acta crystallographica. Section A, Foundations of crystallography, 1993-08, Vol.49 (s1), p.c156-c156

1993

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X-Ray Superflares from Pre-main-sequence Stars: Flare Modeling

The Astrophysical journal, 2021-10, Vol.920 (2), p.154

2021

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ChemInform Abstract: Selective Metal‐Catalyzed Autoxidation of 2‐Arylpropionaldehydes. An Improved Synthesis of Ibuprofen

ChemInform, 1987-08, Vol.18 (32), p.no-no

1987

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Suicide inhibition of canine myocardial cytosolic calcium-independent phospholipase A2. Mechanism-based discrimination between calcium-dependent and -independent phospholipases A2

Kinetic and structural evidence for a sequential ordered Bi Bi mechanism of catalysis by Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase

Discovery of a novel class of potent HIV-1 protease inhibitors containing the (R)-(hydroxyethyl)urea isostere

Design and Synthesis of Novel Imidazole-Substituted Dipeptide Amides as Potent and Selective Inhibitors of Candida albicans MyristoylCoA:Protein N-Myristoyltransferase and Identification of Related Tripeptide Inhibitors with Mechanism-Based Antifungal Activity

Conformationally Constrained [p-(ω-Aminoalkyl)phenacetyl]-l-seryl-l-lysyl Dipeptide Amides as Potent Peptidomimetic Inhibitors of Candida albicans and Human Myristoyl-CoA:Protein N-Myristoyl Transferase

Design and Syntheses of Potent and Selective Dipeptide Inhibitors of Candida albicans Myristoyl-CoA:Protein N-Myristoyltransferase

Discovery of a novel series of selective MMP inhibitors: Identification of the γ-sulfone-thiols

Structural determinants of haloenol lactone-mediated suicide inhibition of canine myocardial calcium-independent phospholipase A2

α-Amino-β-sulphone hydroxamates as potent MMP-13 inhibitors that spare MMP-1

A Convenient Asymmetric Synthesis of the Unnatural Amino Acid 2,6-Dimethyl-L-tyrosine

α-Alkyl-α-amino-β-sulphone hydroxamates as potent MMP inhibitors that spare MMP-1

Selective metal-catalyzed autoxidation of 2-arylpropionaldehydes. An improved synthesis of ibuprofen

Selective peptidic and peptidomimetic inhibitors of Candida albicans myristoylCoA: Protein N-myristoyltransferase: A new approach to antifungal therapy

N-myristoylation of Arf proteins in Candida albicans: an in vivo assay for evaluating antifungal inhibitors of myristoyl-CoA: protein N-myristoyltransferase

Inhibitors of HIV-1 Protease Containing the Novel and Potent (R)-(Hydroxyethyl)sulfonamide Isostere

Synthesis and Structure−Activity Relationships of β- and α-Piperidine Sulfone Hydroxamic Acid Matrix Metalloproteinase Inhibitors with Oral Antitumor Efficacy

Influence of polyfluorination of the phenylalanine ring of angiotensin II on conformation and biological activity

Discovery of novel benzothiazolesulfonamides as potent inhibitors of HIV-1 protease

Replacements for lysine in l-seryl- l-lysyl dipeptide amide inhibitors of candida albicans myristoyl-CoA:protein N-myristoyltransferase

Scanning alanine mutagenesis and de-peptidization of a Candida albicans myristoyl-CoA:protein N-myristoyltransferase octapeptide substrate reveals three elements critical for molecular recognition

Selective functionalization of the C2 hydroxyl group of N-carbobenzyloxy-4,6-Q-benzylidene-1-deoxynojirimycin

(Hydroxyethyl) sulfonamide HIV-1 Protease inhibitors: Identification of the 2-methylbenzoyl moiety at P-2

Binding of the hydroxyethyl-urea isostere to HIV-1 protease

X-Ray Superflares from Pre-main-sequence Stars: Flare Modeling

ChemInform Abstract: Selective Metal‐Catalyzed Autoxidation of 2‐Arylpropionaldehydes. An Improved Synthesis of Ibuprofen

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