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Identification of a Potent and Selective Synthetic Agonist at the CRTH2 Receptor

Molecular pharmacology, 2005-06, Vol.67 (6), p.1834-1839

2005

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High-Sensitivity NanoLC−MS/MS Analysis of Urinary Desmosine and Isodesmosine

Analytical chemistry (Washington), 2009-03, Vol.81 (5), p.1881-1887

2009

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Expression of prostaglandin D synthase and the prostaglandin D2 receptors DP and CRTH2 in human nasal mucosa

Prostaglandins & other lipid mediators, 2004-01, Vol.73 (1-2), p.87-101

2004

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Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi

Nature cell biology, 2002-02, Vol.4 (2), p.95-105

2002

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Caspase-3 cleaves the formin-homology-domain-containing protein FHOD1 during apoptosis to generate a C-terminal fragment that is targeted to the nucleolus

Apoptosis (London), 2006-11, Vol.11 (11), p.1863-1876

2006

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Selective modulation of chemokinesis, degranulation, and apoptosis in eosinophils through the PGD2 receptors CRTH2 and DP

Journal of allergy and clinical immunology, 2001-12, Vol.108 (6), p.982-988

2001

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Pharmacological characterization of MK-7246, a potent and selective CRTH2 (chemoattractant receptor-homologous molecule expressed on T-helper type 2 cells) antagonist

Molecular pharmacology, 2011-01, Vol.79 (1), p.69-76

2011

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Molecular pharmacology of the human prostaglandin D 2 receptor, CRTH2

British journal of pharmacology, 2002-12, Vol.137 (8), p.1163-1172

2002

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Anti-inflammatory actions of Chemoattractant Receptor-homologous molecule expressed on Th2 by the antagonist MK-7246 in a novel rat model of Alternaria alternata elicited pulmonary inflammation

European journal of pharmacology, 2014-11, Vol.743, p.106-116

2014

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The C3a receptor antagonist SB 290157 has agonist activity

Immunology Letters, 2005-09, Vol.100 (2), p.139-145

2005

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Huntingtin Interacting Protein 1 Induces Apoptosis via a Novel Caspase-dependent Death Effector Domain

The Journal of biological chemistry, 2000-12, Vol.275 (52), p.41299-41308

2000

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Identification of Distinct Plasma Biomarker Signatures in Patients with Rapid and Slow Declining Forms of COPD

Chronic obstructive pulmonary disease, 2011-02, Vol.7 (1), p.51-58

2011

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Design, synthesis, and evaluation of novel 3-amino-4-hydrazine-cyclobut-3-ene-1,2-diones as potent and selective CXCR2 chemokine receptor antagonists

Bioorganic & medicinal chemistry letters, 2009-10, Vol.19 (19), p.5741-5745

2009

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Caspases Cleave Focal Adhesion Kinase during Apoptosis to Generate a FRNK-like Polypeptide

The Journal of biological chemistry, 1998-07, Vol.273 (27), p.17102-17108

1998

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Expression of prostaglandin D synthase and the prostaglandin D 2 receptors DP and CRTH2 in human nasal mucosa

Prostaglandins & other lipid mediators, 2004, Vol.73 (1), p.87-101

2004

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Ntk: A Csk-Related Protein-Tyrosine Kinase Expressed in Brain and T Lymphocytes

Proceedings of the National Academy of Sciences - PNAS, 1994-05, Vol.91 (11), p.4975-4979

1994

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Interactions of CD45-associated Protein with the Antigen Receptor Signaling Machinery in T-lymphocytes

The Journal of biological chemistry, 1999-05, Vol.274 (20), p.14392-14399

1999

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Molecular pharmacology of the human prostaglandin D2 receptor, CRTH2

British journal of pharmacology, 2002-12, Vol.137 (8), p.1163-1172

2002

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Reconstitution of interactions between protein-tyrosine phosphatase CD45 and tyrosine-protein kinase p56(lck) in nonlymphoid cells

The Journal of biological chemistry, 1997-05, Vol.272 (19), p.12754-12761

1997

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Interactions of the SH2 domain of lymphocyte-specific tyrosine protein kinase p56lck with phosphotyrosine-containing proteins

Oncogene, 1993-10, Vol.8 (10), p.2765-2772

1993

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The Unique Amino-Terminal Domain of p56 lck Regulates Interactions with Tyrosine Protein Phosphatases in T Lymphocytes

Molecular and cellular biology, 1995-05, Vol.15 (5), p.2393-2401

1995

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Identification, cloning, and characterization of rcsF, a new regulator gene for exopolysaccharide synthesis that suppresses the division mutation ftsZ84 in Escherichia coli K-12

Journal of Bacteriology, 1992-12, Vol.174 (24), p.8016-8022

1992

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Identification of a Potent and Selective Synthetic Agonist at the CRTH2 Receptor

High-Sensitivity NanoLC−MS/MS Analysis of Urinary Desmosine and Isodesmosine

Expression of prostaglandin D synthase and the prostaglandin D2 receptors DP and CRTH2 in human nasal mucosa

Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi

Caspase-3 cleaves the formin-homology-domain-containing protein FHOD1 during apoptosis to generate a C-terminal fragment that is targeted to the nucleolus

Discovery of MK-7246, a selective CRTH2 antagonist for the treatment of respiratory diseases

Selective modulation of chemokinesis, degranulation, and apoptosis in eosinophils through the PGD2 receptors CRTH2 and DP

Pharmacological characterization of MK-7246, a potent and selective CRTH2 (chemoattractant receptor-homologous molecule expressed on T-helper type 2 cells) antagonist

Molecular pharmacology of the human prostaglandin D 2 receptor, CRTH2

Anti-inflammatory actions of Chemoattractant Receptor-homologous molecule expressed on Th2 by the antagonist MK-7246 in a novel rat model of Alternaria alternata elicited pulmonary inflammation

Involvement of Caspases in Proteolytic Cleavage of Alzheimer’s Amyloid-β Precursor Protein and Amyloidogenic Aβ Peptide Formation

The C3a receptor antagonist SB 290157 has agonist activity

Huntingtin Interacting Protein 1 Induces Apoptosis via a Novel Caspase-dependent Death Effector Domain

Identification of Distinct Plasma Biomarker Signatures in Patients with Rapid and Slow Declining Forms of COPD

Design, synthesis, and evaluation of novel 3-amino-4-hydrazine-cyclobut-3-ene-1,2-diones as potent and selective CXCR2 chemokine receptor antagonists

Caspases Cleave Focal Adhesion Kinase during Apoptosis to Generate a FRNK-like Polypeptide

Expression of prostaglandin D synthase and the prostaglandin D 2 receptors DP and CRTH2 in human nasal mucosa

Discovery of Mix-7246, a selective CRTH2 antagonist for the treatment of respiratory diseases

Ntk: A Csk-Related Protein-Tyrosine Kinase Expressed in Brain and T Lymphocytes

Interactions of CD45-associated Protein with the Antigen Receptor Signaling Machinery in T-lymphocytes

Molecular pharmacology of the human prostaglandin D2 receptor, CRTH2

Reconstitution of interactions between protein-tyrosine phosphatase CD45 and tyrosine-protein kinase p56(lck) in nonlymphoid cells

Interactions of the SH2 domain of lymphocyte-specific tyrosine protein kinase p56lck with phosphotyrosine-containing proteins

The Unique Amino-Terminal Domain of p56 lck Regulates Interactions with Tyrosine Protein Phosphatases in T Lymphocytes

Identification, cloning, and characterization of rcsF, a new regulator gene for exopolysaccharide synthesis that suppresses the division mutation ftsZ84 in Escherichia coli K-12

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