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Polyamines and cancer: old molecules, new understanding

Nature reviews. Cancer, 2004-10, Vol.4 (10), p.781-792

2004

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Polyamine-dependent gene expression

Cellular and molecular life sciences : CMLS, 2003-07, Vol.60 (7), p.1394-1406

2003

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Development of Difluoromethylornithine (DFMO) as a Chemoprevention Agent

Clinical cancer research, 1999-05, Vol.5 (5), p.945-951

1999

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Induction of spermidine/spermine N 1-acetyltransferase (SSAT) by aspirin in Caco-2 colon cancer cells

Biochemical journal, 2006-02, Vol.394 (1), p.317-324

2006

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Cyclooxygenase-independent Induction of Apoptosis by Sulindac Sulfone Is Mediated by Polyamines in Colon Cancer

The Journal of biological chemistry, 2003-11, Vol.278 (48), p.47762-47775

2003

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Pronounced Reduction in Adenoma Recurrence Associated with Aspirin Use and a Polymorphism in the Ornithine Decarboxylase Gene

Proceedings of the National Academy of Sciences - PNAS, 2003-06, Vol.100 (13), p.7859-7864

2003

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Emerging Concepts in Targeting the Polyamine Metabolic Pathway in Epithelial Cancer Chemoprevention and Chemotherapy

Journal of biochemistry (Tokyo), 2006, Vol.139 (1), p.27-33

2006

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Endoscopic optical coherence tomography and laser-induced fluorescence spectroscopy in a murine colon cancer model

Lasers in surgery and medicine, 2006-04, Vol.38 (4), p.305-313

2006

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Polyamines as modifiers of genetic risk factors in human intestinal cancers

Biochemical Society transactions, 2003-04, Vol.31 (2), p.388-392

2003

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Effect of α-Difluoromethylornithine on Rectal Mucosal Levels of Polyamines in a Randomized, Double-Blinded Trial for Colon Cancer Prevention

JNCI : Journal of the National Cancer Institute, 1998-08, Vol.90 (16), p.1212-1218

1998

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Task-based imaging of colon cancer in the Apc(Min/+) mouse model

Applied optics (2004), 2006-05, Vol.45 (13), p.3049

2006

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Suppression of polyamine catabolism by activated Ki-ras in human colon cancer cells

Molecular carcinogenesis, 2004-02, Vol.39 (2), p.91-102

2004

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Inhibition of human ornithine decarboxylase activity by enantiomers of difluoromethylornithine

Biochemical journal, 2003-10, Vol.375 (Pt 2), p.465-470

2003

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Different bile acids exhibit distinct biological effects: The tumor promoter deoxycholic acid induces apoptosis and the chemopreventive agent ursodeoxycholic acid inhibits cell proliferation

Nutrition and cancer, 1998-01, Vol.31 (2), p.111-118

1998

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Polyamine-mediated post-transcriptional regulation of COX-2

Biochimie, 2002-08, Vol.84 (8), p.815-819

2002

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The chemopreventive agent α-difluoromethylornithine blocks Ki-ras-dependent tumor formation and specific gene expression in Caco-2 cells

Molecular carcinogenesis, 2004-04, Vol.39 (4), p.221-233

2004

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APC-dependent regulation of ornithine decarboxylase in human colon tumor cells

Molecular carcinogenesis, 2002-05, Vol.34 (1), p.10-18

2002

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APC-dependent changes in expression of genes influencing polyamine metabolism, and consequences for gastrointestinal carcinogenesis, in the Min mouse

Carcinogenesis (New York), 1999-09, Vol.20 (9), p.1709-1713

1999

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A Comprehensive Strategy to Combat Colon Cancer Targeting the Adenomatous Polyposis Coli Tumor Suppressor Gene

Annals of the New York Academy of Sciences, 2005-11, Vol.1059 (1), p.97-105

2005

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The role of NO synthases in arginine-dependent small intestinal and colonic carcinogenesis

Molecular carcinogenesis, 2006-02, Vol.45 (2), p.93-105

2006

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Excess putrescine accumulation inhibits the formation of modified eukaryotic initiation factor 5A (eIF-5A) and induces apoptosis

Biochemical journal, 1997-12, Vol.328 ( Pt 3) (3), p.847-854

1997

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Changing winds in the war on cancer

Cancer biology & therapy, 2005-02, Vol.4 (2), p.260-262

Gerner, Eugene W.

2005

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Increased thioredoxin-1 inhibits SSAT expression in MCF-7 human breast cancer cells

Biochemical and biophysical research communications, 2003-06, Vol.306 (2), p.469-475

2003

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Influence of K-ras Activation on the Survival Responses of Caco-2 Cells to the Chemopreventive Agents Sulindac and Difluoromethylornithine

Cancer epidemiology, biomarkers & prevention, 2000-11, Vol.9 (11), p.1155-1162

2000

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Regulation of the HIV1 long terminal repeat by mutant heat shock factor

Experimental cell research, 2003-08, Vol.288 (1), p.1-8

2003

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Polyamines and cancer: old molecules, new understanding

Polyamine-dependent gene expression

Development of Difluoromethylornithine (DFMO) as a Chemoprevention Agent

Induction of spermidine/spermine N 1-acetyltransferase (SSAT) by aspirin in Caco-2 colon cancer cells

Cyclooxygenase-independent Induction of Apoptosis by Sulindac Sulfone Is Mediated by Polyamines in Colon Cancer

Pronounced Reduction in Adenoma Recurrence Associated with Aspirin Use and a Polymorphism in the Ornithine Decarboxylase Gene

Emerging Concepts in Targeting the Polyamine Metabolic Pathway in Epithelial Cancer Chemoprevention and Chemotherapy

Endoscopic optical coherence tomography and laser-induced fluorescence spectroscopy in a murine colon cancer model

Polyamines as modifiers of genetic risk factors in human intestinal cancers

Effect of α-Difluoromethylornithine on Rectal Mucosal Levels of Polyamines in a Randomized, Double-Blinded Trial for Colon Cancer Prevention

Task-based imaging of colon cancer in the Apc(Min/+) mouse model

Suppression of polyamine catabolism by activated Ki-ras in human colon cancer cells

Inhibition of human ornithine decarboxylase activity by enantiomers of difluoromethylornithine

Different bile acids exhibit distinct biological effects: The tumor promoter deoxycholic acid induces apoptosis and the chemopreventive agent ursodeoxycholic acid inhibits cell proliferation

Polyamine-mediated post-transcriptional regulation of COX-2

The chemopreventive agent α-difluoromethylornithine blocks Ki-ras-dependent tumor formation and specific gene expression in Caco-2 cells

APC-dependent regulation of ornithine decarboxylase in human colon tumor cells

APC-dependent changes in expression of genes influencing polyamine metabolism, and consequences for gastrointestinal carcinogenesis, in the Min mouse

A Comprehensive Strategy to Combat Colon Cancer Targeting the Adenomatous Polyposis Coli Tumor Suppressor Gene

The role of NO synthases in arginine-dependent small intestinal and colonic carcinogenesis

Excess putrescine accumulation inhibits the formation of modified eukaryotic initiation factor 5A (eIF-5A) and induces apoptosis

Changing winds in the war on cancer

Increased thioredoxin-1 inhibits SSAT expression in MCF-7 human breast cancer cells

Influence of K-ras Activation on the Survival Responses of Caco-2 Cells to the Chemopreventive Agents Sulindac and Difluoromethylornithine

Regulation of the HIV1 long terminal repeat by mutant heat shock factor

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