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Role of dietary polyamines in a phase III clinical trial of difluoromethylornithine (DFMO) and sulindac for prevention of sporadic colorectal adenomas

British journal of cancer, 2013-02, Vol.108 (3), p.512-518

2013

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Polyamine-dependent gene expression

Cellular and molecular life sciences : CMLS, 2003-07, Vol.60 (7), p.1394-1406

2003

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Development of Difluoromethylornithine (DFMO) as a Chemoprevention Agent

Clinical cancer research, 1999-05, Vol.5 (5), p.945-951

1999

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Rationale for, and design of, a clinical trial targeting polyamine metabolism for colon cancer chemoprevention

Amino acids, 2007-08, Vol.33 (2), p.189-195

2007

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Polyamines as modifiers of genetic risk factors in human intestinal cancers

Biochemical Society transactions, 2003-04, Vol.31 (2), p.388-392

2003

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Impact of dietary amino acids and polyamines on intestinal carcinogenesis and chemoprevention in mouse models

Biochemical Society transactions, 2007-04, Vol.35 (Pt 2), p.322-325

Gerner, E W

2007

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Effect of α-Difluoromethylornithine on Rectal Mucosal Levels of Polyamines in a Randomized, Double-Blinded Trial for Colon Cancer Prevention

JNCI : Journal of the National Cancer Institute, 1998-08, Vol.90 (16), p.1212-1218

1998

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Different bile acids exhibit distinct biological effects: The tumor promoter deoxycholic acid induces apoptosis and the chemopreventive agent ursodeoxycholic acid inhibits cell proliferation

Nutrition and cancer, 1998-01, Vol.31 (2), p.111-118

1998

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APC-dependent changes in expression of genes influencing polyamine metabolism, and consequences for gastrointestinal carcinogenesis, in the Min mouse

Carcinogenesis (New York), 1999-09, Vol.20 (9), p.1709-1713

1999

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Cyclooxygenase-independent Induction of Apoptosis by Sulindac Sulfone Is Mediated by Polyamines in Colon Cancer

The Journal of biological chemistry, 2003-11, Vol.278 (48), p.47762-47775

2003

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Pronounced Reduction in Adenoma Recurrence Associated with Aspirin Use and a Polymorphism in the Ornithine Decarboxylase Gene

Proceedings of the National Academy of Sciences - PNAS, 2003-06, Vol.100 (13), p.7859-7864

2003

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Heat-inducible vectors for use in gene therapy

International journal of hyperthermia, 2000, Vol.16 (2), p.171-181

2000

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Increased thioredoxin-1 inhibits SSAT expression in MCF-7 human breast cancer cells

Biochemical and biophysical research communications, 2003-06, Vol.306 (2), p.469-475

2003

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Sulindac sulfone inhibits K-ras-dependent cyclooxygenase-2 expression in human colon cancer cells

Cancer research (Chicago, Ill.), 2000-12, Vol.60 (23), p.6607-6610

2000

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Surrogate end-point biomarkers as measures of colon cancer risk and their use in cancer chemoprevention trials

Cancer epidemiology, biomarkers & prevention, 1997-01, Vol.6 (1), p.37

1997

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Heat shock proteins in thermotolerance and other cellular processes

Cancer research (Chicago, Ill.), 1987-10, Vol.47 (20), p.5249-5255

1987

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Suppression of polyamine catabolism by activated Ki-ras in human colon cancer cells

Molecular carcinogenesis, 2004-02, Vol.39 (2), p.91-102

2004

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Polyamines and cancer: old molecules, new understanding

Nature reviews. Cancer, 2004-10, Vol.4 (10), p.781-792

2004

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Chemoprevention by difluoromethylornithine: correlation of an in vitro human cell assay with human clinical data for biomarker modulation

Anticancer research, 2001-03, Vol.21 (2A), p.1163

2001

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The chemopreventive agent α-difluoromethylornithine blocks Ki-ras-dependent tumor formation and specific gene expression in Caco-2 cells

Molecular carcinogenesis, 2004-04, Vol.39 (4), p.221-233

2004

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APC-dependent regulation of ornithine decarboxylase in human colon tumor cells

Molecular carcinogenesis, 2002-05, Vol.34 (1), p.10-18

2002

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Hypusine formation in protein by a two-step process in cell lysates

The Journal of biological chemistry, 1987-11, Vol.262 (31), p.15033-15036

1987

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Excess putrescine accumulation inhibits the formation of modified eukaryotic initiation factor 5A (eIF-5A) and induces apoptosis

Biochemical journal, 1997-12, Vol.328 ( Pt 3) (3), p.847-854

1997

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Ornithine decarboxylase and polyamines in colorectal neoplasia and mucosa

Cancer epidemiology, biomarkers & prevention, 1993-07, Vol.2 (4), p.369

1993

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Effects of cycloheximide on thermotolerance expression, heat shock protein synthesis, and heat shock protein mRNA accumulation in rat fibroblasts

Molecular and Cellular Biology, 1986-04, Vol.6 (4), p.1088-1094

1986

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Role of dietary polyamines in a phase III clinical trial of difluoromethylornithine (DFMO) and sulindac for prevention of sporadic colorectal adenomas

Polyamine-dependent gene expression

Development of Difluoromethylornithine (DFMO) as a Chemoprevention Agent

Rationale for, and design of, a clinical trial targeting polyamine metabolism for colon cancer chemoprevention

Polyamines as modifiers of genetic risk factors in human intestinal cancers

Impact of dietary amino acids and polyamines on intestinal carcinogenesis and chemoprevention in mouse models

Effect of α-Difluoromethylornithine on Rectal Mucosal Levels of Polyamines in a Randomized, Double-Blinded Trial for Colon Cancer Prevention

Different bile acids exhibit distinct biological effects: The tumor promoter deoxycholic acid induces apoptosis and the chemopreventive agent ursodeoxycholic acid inhibits cell proliferation

APC-dependent changes in expression of genes influencing polyamine metabolism, and consequences for gastrointestinal carcinogenesis, in the Min mouse

Cyclooxygenase-independent Induction of Apoptosis by Sulindac Sulfone Is Mediated by Polyamines in Colon Cancer

Pronounced Reduction in Adenoma Recurrence Associated with Aspirin Use and a Polymorphism in the Ornithine Decarboxylase Gene

Heat-inducible vectors for use in gene therapy

Increased thioredoxin-1 inhibits SSAT expression in MCF-7 human breast cancer cells

Sulindac sulfone inhibits K-ras-dependent cyclooxygenase-2 expression in human colon cancer cells

Surrogate end-point biomarkers as measures of colon cancer risk and their use in cancer chemoprevention trials

Heat shock proteins in thermotolerance and other cellular processes

Suppression of polyamine catabolism by activated Ki-ras in human colon cancer cells

Polyamines and cancer: old molecules, new understanding

Chemoprevention by difluoromethylornithine: correlation of an in vitro human cell assay with human clinical data for biomarker modulation

The chemopreventive agent α-difluoromethylornithine blocks Ki-ras-dependent tumor formation and specific gene expression in Caco-2 cells

APC-dependent regulation of ornithine decarboxylase in human colon tumor cells

Hypusine formation in protein by a two-step process in cell lysates

Excess putrescine accumulation inhibits the formation of modified eukaryotic initiation factor 5A (eIF-5A) and induces apoptosis

Ornithine decarboxylase and polyamines in colorectal neoplasia and mucosa

Effects of cycloheximide on thermotolerance expression, heat shock protein synthesis, and heat shock protein mRNA accumulation in rat fibroblasts

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