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P38α MAPK Signaling-A Robust Therapeutic Target for Rab5-Mediated Neurodegenerative Disease

International journal of molecular sciences, 2020-07, Vol.21 (15), p.5485

2020

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Preclinical and randomized clinical evaluation of the p38α kinase inhibitor neflamapimod for basal forebrain cholinergic degeneration

Nature communications, 2022-09, Vol.13 (1), p.5308-5308, Article 5308

2022

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Targeting the MAPK Signaling Pathway in Cancer: Promising Preclinical Activity with the Novel Selective ERK1/2 Inhibitor BVD-523 (Ulixertinib)

Molecular cancer therapeutics, 2017-11, Vol.16 (11), p.2351-2363

2017

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Continuous administration of a p38α inhibitor during the subacute phase after transient ischemia-induced stroke in the rat promotes dose-dependent functional recovery accompanied by increase in brain BDNF protein level

PloS one, 2020-12, Vol.15 (12), p.e0233073

2020

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Extracellular Signal-Regulated Kinase 2 Is Necessary for Mesoderm Differentiation

Proceedings of the National Academy of Sciences - PNAS, 2003-10, Vol.100 (22), p.12759-12764

2003

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Structure-Guided Design of Potent and Selective Pyrimidylpyrrole Inhibitors of Extracellular Signal-Regulated Kinase (ERK) Using Conformational Control

Journal of medicinal chemistry, 2009-10, Vol.52 (20), p.6362-6368

2009

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Subcutaneous Dislocated Hard Contact Lens with Necrosis of the Tarsus

Klinische Monatsblätter für Augenheilkunde, 2019-04, Vol.236 (4), p.417-418

2019

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Ophthalmika in der Schwangerschaft

Die Ophthalmologie, 2024-04, Vol.121 (4), p.333-348

2024

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Novel Ranking System for Identifying Efficacious Anti-Influenza Virus PB2 Inhibitors

Antimicrobial agents and chemotherapy, 2015-10, Vol.59 (10), p.6007-6016

2015

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Flipped Out: Structure-Guided Design of Selective Pyrazolylpyrrole ERK Inhibitors

Journal of medicinal chemistry, 2007-03, Vol.50 (6), p.1280-1287

2007

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c-Jun N-Terminal Kinases Mediate Reactivation of Akt and Cardiomyocyte Survival After Hypoxic Injury In Vitro and In Vivo

Circulation research, 2006-01, Vol.98 (1), p.111-118

2006

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The Discovery of VX-745: A Novel and Selective p38α Kinase Inhibitor

ACS medicinal chemistry letters, 2011-10, Vol.2 (10), p.758-763

2011

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Regulation of inosine monophosphate dehydrogenase type I and type II isoforms in human lymphocytes

Biochemical pharmacology, 2004-02, Vol.67 (4), p.767-776

2004

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Janus Kinase 2 Inhibitors. Synthesis and Characterization of a Novel Polycyclic Azaindole

Journal of medicinal chemistry, 2009-12, Vol.52 (24), p.7938-7941

2009

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Survival of the Scandinavian Total Ankle Replacement (STAR)

Foot & ankle orthopaedics, 2018-09, Vol.3 (3)

2018

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Both ATP Sites of Human P-Glycoprotein Are Essential but Not Symmetric

Biochemistry (Easton), 1999-10, Vol.38 (42), p.13887-13899

1999

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Analyzing radiotelemetry data with a mixed model statistical analysis

Journal of pharmacological and toxicological methods, 2011-07, Vol.64 (1), p.e36-e37

2011

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Survival of the Scandinavian total ankle replacement (STAR): results of ten to nineteen years follow-up

International orthopaedics, 2017-10, Vol.41 (10), p.2075-2082

2017

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Corneal crosslinking for therapy‐resistant keratitis with corneal melting; it is never too late

Acta ophthalmologica (Oxford, England), 2019-12, Vol.97 (S263), p.n/a

2019

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Corneal Cross-Linking (CXL) for Therapy-Resistant Keratitis with Corneal Melting: It Is Never Too Late

Klinische Monatsblätter für Augenheilkunde, 2020-04, Vol.237 (4), p.419-422

2020

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Mutter! Mittlerin zwischen Deinem Kind und der Welt!: Zu Pestalozzis Mutterbild

Germann-Müller, Ursula

1996

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Chemosensitization and drug accumulation effects of VX-710, verapamil, cyclosporin A, MS-209 and GF120918 in multidrug resistant HL60/ADR cells expressing the multidrug resistance-associated protein MRP

Anti-cancer drugs, 1997-02, Vol.8 (2), p.141-155

1997

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Structural Flexibility of the Linker Region of Human P-Glycoprotein Permits ATP Hydrolysis and Drug Transport

Biochemistry (Easton), 1998-09, Vol.37 (39), p.13660-13673

1998

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Rat spontaneous motor activity, a sensitive first-tier screen of CNS safety for early-drug discovery

Journal of pharmacological and toxicological methods, 2013-07, Vol.68 (1), p.e4-e4

2013

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Discovery of a Novel, First-in-Class, Orally Bioavailable Azaindole Inhibitor (VX-787) of Influenza PB2

Journal of medicinal chemistry, 2014-08, Vol.57 (15), p.6668-6678

2014

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P38α MAPK Signaling-A Robust Therapeutic Target for Rab5-Mediated Neurodegenerative Disease

Preclinical and randomized clinical evaluation of the p38α kinase inhibitor neflamapimod for basal forebrain cholinergic degeneration

Targeting the MAPK Signaling Pathway in Cancer: Promising Preclinical Activity with the Novel Selective ERK1/2 Inhibitor BVD-523 (Ulixertinib)

Continuous administration of a p38α inhibitor during the subacute phase after transient ischemia-induced stroke in the rat promotes dose-dependent functional recovery accompanied by increase in brain BDNF protein level

Extracellular Signal-Regulated Kinase 2 Is Necessary for Mesoderm Differentiation

Structure-Guided Design of Potent and Selective Pyrimidylpyrrole Inhibitors of Extracellular Signal-Regulated Kinase (ERK) Using Conformational Control

Subcutaneous Dislocated Hard Contact Lens with Necrosis of the Tarsus

Ophthalmika in der Schwangerschaft

Novel Ranking System for Identifying Efficacious Anti-Influenza Virus PB2 Inhibitors

Flipped Out: Structure-Guided Design of Selective Pyrazolylpyrrole ERK Inhibitors

c-Jun N-Terminal Kinases Mediate Reactivation of Akt and Cardiomyocyte Survival After Hypoxic Injury In Vitro and In Vivo

The Discovery of VX-745: A Novel and Selective p38α Kinase Inhibitor

Regulation of inosine monophosphate dehydrogenase type I and type II isoforms in human lymphocytes

Janus Kinase 2 Inhibitors. Synthesis and Characterization of a Novel Polycyclic Azaindole

Survival of the Scandinavian Total Ankle Replacement (STAR)

Both ATP Sites of Human P-Glycoprotein Are Essential but Not Symmetric

Analyzing radiotelemetry data with a mixed model statistical analysis

Survival of the Scandinavian total ankle replacement (STAR): results of ten to nineteen years follow-up

Corneal crosslinking for therapy‐resistant keratitis with corneal melting; it is never too late

Corneal Cross-Linking (CXL) for Therapy-Resistant Keratitis with Corneal Melting: It Is Never Too Late

Mutter! Mittlerin zwischen Deinem Kind und der Welt!: Zu Pestalozzis Mutterbild

Chemosensitization and drug accumulation effects of VX-710, verapamil, cyclosporin A, MS-209 and GF120918 in multidrug resistant HL60/ADR cells expressing the multidrug resistance-associated protein MRP

Structural Flexibility of the Linker Region of Human P-Glycoprotein Permits ATP Hydrolysis and Drug Transport

Rat spontaneous motor activity, a sensitive first-tier screen of CNS safety for early-drug discovery

Discovery of a Novel, First-in-Class, Orally Bioavailable Azaindole Inhibitor (VX-787) of Influenza PB2

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