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Molecular Mechanism of Action of Monocyclam Versus Bicyclam Non-peptide Antagonists in the CXCR4 Chemokine Receptor

The Journal of biological chemistry, 2007-09, Vol.282 (37), p.27354-27365

2007

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Inhibition of demethylases by GSK-J1/J4

Nature (London), 2014-10, Vol.514 (7520), p.E1-E2

2014

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Metal Ion Site Engineering Indicates a Global Toggle Switch Model for Seven-transmembrane Receptor Activation

The Journal of biological chemistry, 2006-06, Vol.281 (25), p.17337-17346

2006

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Inhibition of Human Immunodeficiency Virus Replication by a Dual CCR5/CXCR4 Antagonist

Journal of Virology, 2004-12, Vol.78 (23), p.12996-13006

2004

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A physicogenetic method to assign ligand-binding relationships between 7TM receptors

Bioorganic & medicinal chemistry letters, 2005-08, Vol.15 (16), p.3707-3712

2005

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GPR39 Signaling Is Stimulated by Zinc Ions But Not by Obestatin

Endocrinology (Philadelphia), 2007-01, Vol.148 (1), p.13-20

2007

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Model-Based Discovery of Synthetic Agonists for the Zn2+-Sensing G‑Protein-Coupled Receptor 39 (GPR39) Reveals Novel Biological Functions

Journal of medicinal chemistry, 2017-02, Vol.60 (3), p.886-898

2017

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Long-Acting Lipidated Analogue of Human Pancreatic Polypeptide Is Slowly Released into Circulation

Journal of medicinal chemistry, 2011-04, Vol.54 (8), p.2658-2667

2011

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Molecular mechanism of AMD3100 antagonism in the CXCR4 receptor: transfer of binding site to the CXCR3 receptor

The Journal of biological chemistry, 2004-01, Vol.279 (4), p.3033-3041

2004

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Molecular Interactions of Cyclam and Bicyclam Non-peptide Antagonists with the CXCR4 Chemokine Receptor

The Journal of biological chemistry, 2001-04, Vol.276 (17), p.14153-14160

2001

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Identification of Indole Derivatives Exclusively Interfering with a G Protein-Independent Signaling Pathway of the Prostaglandin D2 Receptor CRTH2

Molecular pharmacology, 2005-08, Vol.68 (2), p.393-402

2005

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Preparation and evaluation of sulfur-containing metal chelators

Organic & biomolecular chemistry, 2003-01, Vol.1 (23), p.4248-4253

2003

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Novel Selective Orally Active CRTH2 Antagonists for Allergic Inflammation Developed from in Silico Derived Hits

Journal of medicinal chemistry, 2006-11, Vol.49 (23), p.6638-6641

2006

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Mutations at the CXCR4 interaction sites for AMD3100 influence anti-CXCR4 antibody binding and HIV-1 entry

FEBS letters, 2003-07, Vol.546 (2), p.300-306

2003

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HER2-positive breast-cancer cell lines are sensitive to KDM5 inhibition: definition of a gene-expression model for the selection of sensitive cases

Oncogene, 2019-04, Vol.38 (15), p.2675-2689

2019

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Molecular Mechanism of AMD3100 Antagonism in the CXCR4 Receptor

The Journal of biological chemistry, 2004-01, Vol.279 (4), p.3033-3041

2004

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Model-Based Discovery of Synthetic Agonists for the Zn 2+ -Sensing G-Protein-Coupled Receptor 39 (GPR39) Reveals Novel Biological Functions

Journal of medicinal chemistry, 2017-02, Vol.60 (3), p.886-898

2017

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Abstract 5161: The development of therapeutic inhibitors of the KDM5 histone demethylases

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.5161-5161

2014

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Metal Ion Enhanced Binding of AMD3100 to Asp262 in the CXCR4 Receptor

Biochemistry (Easton), 2003-01, Vol.42 (3), p.710-717

2003

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Mutation of Asp(171) and Asp(262) of the chemokine receptor CXCR4 impairs its coreceptor function for human immunodeficiency virus-1 entry and abrogates the antagonistic activity of AMD3100

Molecular pharmacology, 2001-07, Vol.60 (1), p.164-173

2001

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Arylamide derivatives as allosteric inhibitors of the integrin α2β1/type I collagen interaction

Bioorganic & medicinal chemistry letters, 2006-07, Vol.16 (13), p.3380-3382

2006

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A physicogenetic method to assign ligand-binding relationships between 7TM receptors: G-protein-coupled receptors in drug discovery

Bioorganic & medicinal chemistry letters, 2005, Vol.15 (16), p.3707-3712

2005

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Arylamide derivatives as allosteric inhibitors of the integrin alpha sub(2) beta sub(1)/type I collagen interaction

Bioorganic & medicinal chemistry letters, 2006-07, Vol.16 (13), p.3380-3382

2006

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Arylamide derivatives as allosteric inhibitors of the integrin alpha2beta1/type I collagen interaction

Bioorganic & medicinal chemistry letters, 2006-07, Vol.16 (13), p.3380-3382

2006

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Molecular Mechanism of Action of Monocyclam Versus Bicyclam Non-peptide Antagonists in the CXCR4 Chemokine Receptor

Inhibition of demethylases by GSK-J1/J4

Metal Ion Site Engineering Indicates a Global Toggle Switch Model for Seven-transmembrane Receptor Activation

Inhibition of Human Immunodeficiency Virus Replication by a Dual CCR5/CXCR4 Antagonist

A physicogenetic method to assign ligand-binding relationships between 7TM receptors

GPR39 Signaling Is Stimulated by Zinc Ions But Not by Obestatin

Model-Based Discovery of Synthetic Agonists for the Zn2+-Sensing G‑Protein-Coupled Receptor 39 (GPR39) Reveals Novel Biological Functions

Long-Acting Lipidated Analogue of Human Pancreatic Polypeptide Is Slowly Released into Circulation

Molecular mechanism of AMD3100 antagonism in the CXCR4 receptor: transfer of binding site to the CXCR3 receptor

Molecular Interactions of Cyclam and Bicyclam Non-peptide Antagonists with the CXCR4 Chemokine Receptor

Identification of Indole Derivatives Exclusively Interfering with a G Protein-Independent Signaling Pathway of the Prostaglandin D2 Receptor CRTH2

Preparation and evaluation of sulfur-containing metal chelators

Novel Selective Orally Active CRTH2 Antagonists for Allergic Inflammation Developed from in Silico Derived Hits

Mutations at the CXCR4 interaction sites for AMD3100 influence anti-CXCR4 antibody binding and HIV-1 entry

HER2-positive breast-cancer cell lines are sensitive to KDM5 inhibition: definition of a gene-expression model for the selection of sensitive cases

Molecular Mechanism of AMD3100 Antagonism in the CXCR4 Receptor

Model-Based Discovery of Synthetic Agonists for the Zn 2+ -Sensing G-Protein-Coupled Receptor 39 (GPR39) Reveals Novel Biological Functions

Abstract 5161: The development of therapeutic inhibitors of the KDM5 histone demethylases

Metal Ion Enhanced Binding of AMD3100 to Asp262 in the CXCR4 Receptor

Inhibition of demethylases by GSK-J1/J4/Kruidenier et al. reply

Mutation of Asp(171) and Asp(262) of the chemokine receptor CXCR4 impairs its coreceptor function for human immunodeficiency virus-1 entry and abrogates the antagonistic activity of AMD3100

Arylamide derivatives as allosteric inhibitors of the integrin α2β1/type I collagen interaction

A physicogenetic method to assign ligand-binding relationships between 7TM receptors: G-protein-coupled receptors in drug discovery

Arylamide derivatives as allosteric inhibitors of the integrin alpha sub(2) beta sub(1)/type I collagen interaction

Arylamide derivatives as allosteric inhibitors of the integrin alpha2beta1/type I collagen interaction

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