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Challenges in inhaled product development and opportunities for open innovation

Advanced drug delivery reviews, 2011-01, Vol.63 (1), p.69-87

2011

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The rapid alveolar absorption of diesel soot-adsorbed benzo[a]pyrene: bioavailability, metabolism and dosimetry of an inhaled particle-borne carcinogen

Carcinogenesis (New York), 2001-05, Vol.22 (5), p.741-749

2001

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In Vitro to ex Vivo/In Vivo Correlation (IVIVC) of dissolution kinetics from inhaled particulate solutes using air/blood barrier models: Relation between in vitro design, lung physiology and kinetic output of models

Journal of aerosol science, 2021-01, Vol.151, p.105698, Article 105698

2021

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Leucine improves the aerosol performance of dry powder inhaler formulations of siRNA-loaded nanoparticles

International journal of pharmaceutics, 2022-06, Vol.621, p.121758-121758, Article 121758

2022

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Daily intake of phthalates, MEHP, and DINCH by ingestion and inhalation

Chemosphere (Oxford), 2018-10, Vol.208, p.40-49

2018

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Development of Combining of Human Bronchial Mucosa Models with XposeALI® for Exposure of Air Pollution Nanoparticles

PloS one, 2017-01, Vol.12 (1), p.e0170428

2017

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Regional lung targeting with a fluticasone/salmeterol aerosol using a bolus breath hold method of the PreciseInhale® system: A first evaluation in humans

European journal of pharmaceutical sciences, 2024-05, Vol.196, p.106742-106742, Article 106742

2024

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Human Alveolar Macrophage Phagocytic Function is Impaired by Aggregates of Ultrafine Carbon Particles

Environmental research, 2001-07, Vol.86 (3), p.244-253

2001

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Multi-cellular human bronchial models exposed to diesel exhaust particles: assessment of inflammation, oxidative stress and macrophage polarization

Particle and fibre toxicology, 2018-05, Vol.15 (1), p.19-19, Article 19

2018

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Integration of mucus and its impact within in vitro setups for inhaled drugs and formulations: Identifying the limits of simple vs. complex methodologies when studying drug dissolution and permeability

International journal of pharmaceutics, 2024-08, Vol.661, p.124455, Article 124455

2024

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Dry powder inhaler formulation comparison: Study of the role of particle deposition pattern and dissolution

International journal of pharmaceutics, 2021-09, Vol.607, p.121025-121025, Article 121025

2021

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Bioavailability of inhaled or ingested PFOA adsorbed to house dust

Environmental science and pollution research international, 2022-11, Vol.29 (52), p.78698-78710

2022

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Isolation and characterization of a respirable particle fraction from residential house-dust

Environmental research, 2018-02, Vol.161, p.284-290

2018

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Cancer Risk Assessment, Indicators, and Guidelines for Polycyclic Aromatic Hydrocarbons in the Ambient Air

Environmental health perspectives, 2002-06, Vol.110 (s3), p.451-488

2002

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Investigation of Lung Pharmacokinetic of the Novel PDE4 Inhibitor CHF6001 in Preclinical Models: Evaluation of the PreciseInhale Technology

Journal of aerosol medicine and pulmonary drug delivery, 2018-02, Vol.31 (1), p.61-70

2018

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Effect of particle deposition density of dry powders on the results produced by an in vitro test system simulating dissolution- and absorption rates in the lungs

European journal of pharmaceutics and biopharmaceutics, 2019-06, Vol.139, p.213-223

2019

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Exposure of normal and chronic bronchitis-like mucosa models to aerosolized carbon nanoparticles: comparison of pro-inflammatory oxidative stress and tissue injury/repair responses

Nanotoxicology, 2019-11, Vol.13 (10), p.1362-1379

2019

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Use of PBPK Modeling To Evaluate the Performance of Dissolv It, a Biorelevant Dissolution Assay for Orally Inhaled Drug Products

Molecular pharmaceutics, 2019-03, Vol.16 (3), p.1245-1254

2019

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Adapting the Aerogen Mesh Nebulizer for Dried Aerosol Exposures Using the PreciseInhale Platform

Journal of aerosol medicine and pulmonary drug delivery, 2020-04, Vol.33 (2), p.116-126

2020

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DissolvIt: An In Vitro Method for Simulating the Dissolution and Absorption of Inhaled Dry Powder Drugs in the Lungs

Assay and drug development technologies, 2017-02, Vol.15 (2), p.77

2017

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Airway Epithelial Lining Fluid and Plasma Pharmacokinetics of Inhaled Fluticasone Propionate and Salmeterol Xinafoate in Mechanically Ventilated Pigs

Journal of aerosol medicine and pulmonary drug delivery, 2021-08, Vol.34 (4), p.231-241

2021

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How do we compare dose to cells in vitro with dose to live animals and humans? Some experiences with inhaled substances

Experimental and toxicologic pathology (Print), 2008-06, Vol.60 (2), p.181-184

Gerde, Per

2008

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Solution-Engineered Palladium Nanoparticles: Model for Health Effect Studies of Automotive Particulate Pollution

ACS nano, 2011-07, Vol.5 (7), p.5312-5324

2011

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Counter-current spray drying with stream separation: Computational modeling of a novel dryer design

Chemical engineering research & design, 2015-01, Vol.93, p.163-173

2015

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Toxicity of lunar dust

Planetary and space science, 2012-12, Vol.74 (1), p.57-71

2012

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Challenges in inhaled product development and opportunities for open innovation

The rapid alveolar absorption of diesel soot-adsorbed benzo[a]pyrene: bioavailability, metabolism and dosimetry of an inhaled particle-borne carcinogen

In Vitro to ex Vivo/In Vivo Correlation (IVIVC) of dissolution kinetics from inhaled particulate solutes using air/blood barrier models: Relation between in vitro design, lung physiology and kinetic output of models

Leucine improves the aerosol performance of dry powder inhaler formulations of siRNA-loaded nanoparticles

Daily intake of phthalates, MEHP, and DINCH by ingestion and inhalation

Development of Combining of Human Bronchial Mucosa Models with XposeALI® for Exposure of Air Pollution Nanoparticles

Regional lung targeting with a fluticasone/salmeterol aerosol using a bolus breath hold method of the PreciseInhale® system: A first evaluation in humans

Human Alveolar Macrophage Phagocytic Function is Impaired by Aggregates of Ultrafine Carbon Particles

Multi-cellular human bronchial models exposed to diesel exhaust particles: assessment of inflammation, oxidative stress and macrophage polarization

Integration of mucus and its impact within in vitro setups for inhaled drugs and formulations: Identifying the limits of simple vs. complex methodologies when studying drug dissolution and permeability

Dry powder inhaler formulation comparison: Study of the role of particle deposition pattern and dissolution

Bioavailability of inhaled or ingested PFOA adsorbed to house dust

Isolation and characterization of a respirable particle fraction from residential house-dust

Cancer Risk Assessment, Indicators, and Guidelines for Polycyclic Aromatic Hydrocarbons in the Ambient Air

Investigation of Lung Pharmacokinetic of the Novel PDE4 Inhibitor CHF6001 in Preclinical Models: Evaluation of the PreciseInhale Technology

Effect of particle deposition density of dry powders on the results produced by an in vitro test system simulating dissolution- and absorption rates in the lungs

Exposure of normal and chronic bronchitis-like mucosa models to aerosolized carbon nanoparticles: comparison of pro-inflammatory oxidative stress and tissue injury/repair responses

Use of PBPK Modeling To Evaluate the Performance of Dissolv It, a Biorelevant Dissolution Assay for Orally Inhaled Drug Products

Adapting the Aerogen Mesh Nebulizer for Dried Aerosol Exposures Using the PreciseInhale Platform

DissolvIt: An In Vitro Method for Simulating the Dissolution and Absorption of Inhaled Dry Powder Drugs in the Lungs

Airway Epithelial Lining Fluid and Plasma Pharmacokinetics of Inhaled Fluticasone Propionate and Salmeterol Xinafoate in Mechanically Ventilated Pigs

How do we compare dose to cells in vitro with dose to live animals and humans? Some experiences with inhaled substances

Solution-Engineered Palladium Nanoparticles: Model for Health Effect Studies of Automotive Particulate Pollution

Counter-current spray drying with stream separation: Computational modeling of a novel dryer design

Toxicity of lunar dust

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