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Characterization of intermediate steps in amyloid beta (Aβ) production under near-native conditions

The Journal of biological chemistry, 2014-01, Vol.289 (3), p.1540-1550

2014

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The proton-pump inhibitor lansoprazole enhances amyloid beta production

PloS one, 2013-03, Vol.8 (3), p.e58837-e58837

2013

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GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Aβ42

The EMBO journal, 2007-03, Vol.26 (6), p.1702-1712

2007

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Amyloid beta 42 peptide (Aβ42)-lowering compounds directly bind to Aβ and interfere with amyloid precursor protein (APP) transmembrane dimerization

Proceedings of the National Academy of Sciences - PNAS, 2010-08, Vol.107 (33), p.14597-14602

2010

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IGF-1-induced Processing of the Amyloid Precursor Protein Family Is Mediated by Different Signaling Pathways

The Journal of biological chemistry, 2007-04, Vol.282 (14), p.10203-10209

2007

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The amyloid precursor protein and its homologues: Structural and functional aspects of native and pathogenic oligomerization

European journal of cell biology, 2012-04, Vol.91 (4), p.234-239

2012

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Dietary Cu Stabilizes Brain Superoxide Dismutase 1 Activity and Reduces Amyloid Aβ Production in APP23 Transgenic Mice

Proceedings of the National Academy of Sciences - PNAS, 2003-11, Vol.100 (24), p.14187-14192

2003

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APP dimer formation is initiated in the endoplasmic reticulum and differs between APP isoforms

Cellular and molecular life sciences : CMLS, 2012-04, Vol.69 (8), p.1353-1375

2012

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Pyroglutamate Abeta pathology in APP/PS1KI mice, sporadic and familial Alzheimer’s disease cases

Journal of Neural Transmission, 2010-01, Vol.117 (1), p.85-96

2010

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Clioquinol Mediates Copper Uptake and Counteracts Copper Efflux Activities of the Amyloid Precursor Protein of Alzheimer's Disease

The Journal of biological chemistry, 2004-12, Vol.279 (50), p.51958-51964

2004

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A Family Knockout of All Four Drosophila Metallothioneins Reveals a Central Role in Copper Homeostasis and Detoxification

Molecular and Cellular Biology, 2006-03, Vol.26 (6), p.2286-2296

2006

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Hippocampal Neuron Loss Exceeds Amyloid Plaque Load in a Transgenic Mouse Model of Alzheimer's Disease

The American journal of pathology, 2004-04, Vol.164 (4), p.1495-1502

2004

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Axonopathy in an APP/PS1 transgenic mouse model of Alzheimer's disease

Acta neuropathologica, 2006-04, Vol.111 (4), p.312-319

2006

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Homodimerization of Amyloid Precursor Protein and Its Implication in the Amyloidogenic Pathway of Alzheimer's Disease

The Journal of biological chemistry, 2001-09, Vol.276 (36), p.33923-33929

2001

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The Amyloid Precursor Protein of Alzheimer's Disease in the Reduction of Copper(II) to Copper(I)

Science (American Association for the Advancement of Science), 1996-03, Vol.271 (5254), p.1406-1409

1996

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Profile of cholesterol-related sterols in aged amyloid precursor protein transgenic mouse brain

Journal of lipid research, 2002-07, Vol.43 (7), p.1078-1085

2002

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Understanding the Interaction of Polyelectrolyte Architectures with Proteins and Biosystems

Angewandte Chemie (International ed.), 2021-02, Vol.60 (8), p.3882-3904

International ed. in English, 2021

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Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice

Brain research, 1999-09, Vol.842 (2), p.439-444

1999

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Disturbed Copper Bioavailability in Alzheimer's Disease

International journal of alzheimer's disease, 2011, Vol.2011, p.345614-5

2011

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Human BACE Forms Dimers and Colocalizes with APP

The Journal of biological chemistry, 2004-09, Vol.279 (38), p.39710-39717

2004

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The Alzheimer's Disease Amyloid Precursor Protein Modulates Copper-Induced Toxicity and Oxidative Stress in Primary Neuronal Cultures

The Journal of neuroscience, 1999-11, Vol.19 (21), p.9170-9179

1999

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Real-time kinetics of discontinuous and highly conformational metal-ion binding sites of prion protein

Journal of biological inorganic chemistry, 2007-06, Vol.12 (5), p.711-720

2007

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Kinetic Analysis of the Interaction of the Copper Chaperone Atox1 with the Metal Binding Sites of the Menkes Protein

The Journal of biological chemistry, 2003-06, Vol.278 (23), p.20821-20827

2003

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The Amyloid Precursor Protein (APP) of Alzheimer Disease and Its Paralog, APLP2, Modulate the Cu/Zn-Nitric Oxide-catalyzed Degradation of Glypican-1 Heparan Sulfate in Vivo

The Journal of biological chemistry, 2005-04, Vol.280 (14), p.13913-13920

2005

Volltextzugriff (PDF)

Wechselwirkung von Polyelektrolyt‐Architekturen mit Proteinen und Biosystemen

Angewandte Chemie, 2021-02, Vol.133 (8), p.3926-3950

2021

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Characterization of intermediate steps in amyloid beta (Aβ) production under near-native conditions

The proton-pump inhibitor lansoprazole enhances amyloid beta production

GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Aβ42

Amyloid beta 42 peptide (Aβ42)-lowering compounds directly bind to Aβ and interfere with amyloid precursor protein (APP) transmembrane dimerization

IGF-1-induced Processing of the Amyloid Precursor Protein Family Is Mediated by Different Signaling Pathways

The amyloid precursor protein and its homologues: Structural and functional aspects of native and pathogenic oligomerization

Dietary Cu Stabilizes Brain Superoxide Dismutase 1 Activity and Reduces Amyloid Aβ Production in APP23 Transgenic Mice

APP dimer formation is initiated in the endoplasmic reticulum and differs between APP isoforms

Pyroglutamate Abeta pathology in APP/PS1KI mice, sporadic and familial Alzheimer’s disease cases

Clioquinol Mediates Copper Uptake and Counteracts Copper Efflux Activities of the Amyloid Precursor Protein of Alzheimer's Disease

A Family Knockout of All Four Drosophila Metallothioneins Reveals a Central Role in Copper Homeostasis and Detoxification

Hippocampal Neuron Loss Exceeds Amyloid Plaque Load in a Transgenic Mouse Model of Alzheimer's Disease

Axonopathy in an APP/PS1 transgenic mouse model of Alzheimer's disease

Homodimerization of Amyloid Precursor Protein and Its Implication in the Amyloidogenic Pathway of Alzheimer's Disease

The Amyloid Precursor Protein of Alzheimer's Disease in the Reduction of Copper(II) to Copper(I)

Profile of cholesterol-related sterols in aged amyloid precursor protein transgenic mouse brain

Understanding the Interaction of Polyelectrolyte Architectures with Proteins and Biosystems

Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice

Disturbed Copper Bioavailability in Alzheimer's Disease

Human BACE Forms Dimers and Colocalizes with APP

The Alzheimer's Disease Amyloid Precursor Protein Modulates Copper-Induced Toxicity and Oxidative Stress in Primary Neuronal Cultures

Real-time kinetics of discontinuous and highly conformational metal-ion binding sites of prion protein

Kinetic Analysis of the Interaction of the Copper Chaperone Atox1 with the Metal Binding Sites of the Menkes Protein

The Amyloid Precursor Protein (APP) of Alzheimer Disease and Its Paralog, APLP2, Modulate the Cu/Zn-Nitric Oxide-catalyzed Degradation of Glypican-1 Heparan Sulfate in Vivo

Wechselwirkung von Polyelektrolyt‐Architekturen mit Proteinen und Biosystemen

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