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High‐Throughput Assessment of Thermal and Colloidal Stability Parameters for Monoclonal Antibody Formulations

Journal of pharmaceutical sciences, 2011-12, Vol.100 (12), p.5126-5141

2011

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High-throughput dynamic light scattering method for measuring viscosity of concentrated protein solutions

Analytical biochemistry, 2010-04, Vol.399 (1), p.141-143

2010

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Screening of Monoclonal Antibody Formulations Based on High-Throughput Thermostability and Viscosity Measurements: Design of Experiment and Statistical Analysis

Journal of pharmaceutical sciences, 2011-04, Vol.100 (4), p.1330-1340

2011

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Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor

The Journal of pharmacology and experimental therapeutics, 2002-06, Vol.301 (3), p.1020-1024

2002

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Detection of IgG Aggregation by a High Throughput Method Based on Extrinsic Fluorescence

Journal of pharmaceutical sciences, 2010-06, Vol.99 (6), p.2598-2608

2010

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Methods of high throughput biophysical characterization in biopharmaceutical development

Current drug discovery technologies, 2013-03, Vol.10 (1), p.59-70

2013

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Characterization of the enzymatic activity of human kallikrein 6: autoactivation, substrate specificity, and regulation by inhibitors

Biochemical and biophysical research communications, 2003-08, Vol.307 (4), p.948-955

2003

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Accelerated formulation development of monoclonal antibodies (mAbs) and mAb-based modalities: review of methods and tools

Journal of biomolecular screening, 2015-04, Vol.20 (4), p.468-483

2015

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Alloxan is an inhibitor of the enzyme O-linked N-acetylglucosamine transferase

Biochemical and biophysical research communications, 2002-04, Vol.293 (1), p.207-212

2002

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Methods of High Throughput Biophysical Characterization in Biopharmaceutical Development

Current drug discovery technologies, 2013-03, Vol.10 (1), p.59-70

2013

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Effects of Sucrose and Benzyl Alcohol on GCSF Conformational Dynamics Revealed by Hydrogen Deuterium Exchange Mass Spectrometry

Journal of pharmaceutical sciences, 2015-05, Vol.104 (5), p.1592-1600

2015

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Design, Synthesis, and Proposed Active Site Binding Analysis of Monocyclic 2-Azetidinone Inhibitors of Prostate Specific Antigen

Journal of medicinal chemistry, 2001-05, Vol.44 (10), p.1491-1508

2001

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High-throughput screening and stability optimization of anti-streptavidin IgG1 and IgG2 formulations

Journal of biomolecular screening, 2014-10, Vol.19 (9), p.1290-1301

2014

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High-Throughput Screening and Analysis of Charge Variants of Monoclonal Antibodies in Multiple Formulations

SLAS discovery, 2017-09, Vol.22 (8), p.1044-1052

2017

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Decoy receptor 3 (DcR3) is proteolytically processed to a metabolic fragment having differential activities against Fas ligand and LIGHT

Biochemical pharmacology, 2003-02, Vol.65 (4), p.657-667

2003

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Increased Sensitivity of Tryptic Peptide Detection by MALDI-TOF Mass Spectrometry Is Achieved by Conversion of Lysine to Homoarginine

Analytical biochemistry, 2000-12, Vol.287 (1), p.110-117

2000

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Isolation and measurement of the endogenous cannabinoid receptor agonist, anandamide, in brain and peripheral tissues of human and rat

FEBS letters, 1996-09, Vol.393 (2), p.231-235

1996

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Stable isotopic labeling of proteins for quantitative proteomic applications

Briefings in functional genomics & proteomics, 2008-09, Vol.7 (5), p.371-382

Becker, Gerald W.

2008

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Mechanisms involved in degradation of human insulin by cytosolic fractions of human, monkey, and rat liver

Diabetes (New York, N.Y.), 1992-04, Vol.41 (4), p.539-547

1992

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Isolation and Characterization of the Principal ATPase Associated with Transitional Endoplasmic Reticulum of Rat Liver

The Journal of cell biology, 1994-12, Vol.127 (6), p.1871-1883

1994

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Leptin is a four-helix bundle: secondary structure by NMR

FEBS letters, 1997-04, Vol.407 (2), p.239-242

1997

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Evidence of free and bound leptin in human circulation. Studies in lean and obese subjects and during short-term fasting

The Journal of clinical investigation, 1996-09, Vol.98 (6), p.1277-1282

1996

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Prostate-specific antigen (PSA)-mediated proliferation, androgenic regulation and inhibitory effects of LY312340 in HOS-TE85 (TE85) human osteosarcoma cells

Anticancer research, 2002-09, Vol.22 (5), p.2725

2002

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Expression, purification, and characterization of active recombinant prostate-specific antigen in Pichia pastoris (yeast)

The Prostate, 2001-03, Vol.46 (4), p.298-306

2001

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Cloning and expression of the fungal expandase/hydroxylase gene involved in cephalosporin biosynthesis

Bio/technology (New York, N.Y. 1983), 1987-11, Vol.5 (11), p.1207-1214

1987

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High‐Throughput Assessment of Thermal and Colloidal Stability Parameters for Monoclonal Antibody Formulations

High-throughput dynamic light scattering method for measuring viscosity of concentrated protein solutions

Screening of Monoclonal Antibody Formulations Based on High-Throughput Thermostability and Viscosity Measurements: Design of Experiment and Statistical Analysis

Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor

Detection of IgG Aggregation by a High Throughput Method Based on Extrinsic Fluorescence

Methods of high throughput biophysical characterization in biopharmaceutical development

Characterization of the enzymatic activity of human kallikrein 6: autoactivation, substrate specificity, and regulation by inhibitors

Accelerated formulation development of monoclonal antibodies (mAbs) and mAb-based modalities: review of methods and tools

Alloxan is an inhibitor of the enzyme O-linked N-acetylglucosamine transferase

Methods of High Throughput Biophysical Characterization in Biopharmaceutical Development

Effects of Sucrose and Benzyl Alcohol on GCSF Conformational Dynamics Revealed by Hydrogen Deuterium Exchange Mass Spectrometry

Design, Synthesis, and Proposed Active Site Binding Analysis of Monocyclic 2-Azetidinone Inhibitors of Prostate Specific Antigen

High-throughput screening and stability optimization of anti-streptavidin IgG1 and IgG2 formulations

High-Throughput Screening and Analysis of Charge Variants of Monoclonal Antibodies in Multiple Formulations

Decoy receptor 3 (DcR3) is proteolytically processed to a metabolic fragment having differential activities against Fas ligand and LIGHT

Increased Sensitivity of Tryptic Peptide Detection by MALDI-TOF Mass Spectrometry Is Achieved by Conversion of Lysine to Homoarginine

Isolation and measurement of the endogenous cannabinoid receptor agonist, anandamide, in brain and peripheral tissues of human and rat

Stable isotopic labeling of proteins for quantitative proteomic applications

Mechanisms involved in degradation of human insulin by cytosolic fractions of human, monkey, and rat liver

Isolation and Characterization of the Principal ATPase Associated with Transitional Endoplasmic Reticulum of Rat Liver

Leptin is a four-helix bundle: secondary structure by NMR

Evidence of free and bound leptin in human circulation. Studies in lean and obese subjects and during short-term fasting

Prostate-specific antigen (PSA)-mediated proliferation, androgenic regulation and inhibitory effects of LY312340 in HOS-TE85 (TE85) human osteosarcoma cells

Expression, purification, and characterization of active recombinant prostate-specific antigen in Pichia pastoris (yeast)

Cloning and expression of the fungal expandase/hydroxylase gene involved in cephalosporin biosynthesis

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