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ADAMTS-8 exhibits aggrecanase activity and is expressed in human articular cartilage

Matrix biology, 2004-07, Vol.23 (4), p.219-230

2004

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Discovery of Novel, Potent Inhibitors of Hydroxy Acid Oxidase 1 (HAO1) Using DNA-Encoded Chemical Library Screening

Journal of medicinal chemistry, 2021-05, Vol.64 (10), p.6730-6744

2021

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Mechanism of Cytochrome c Oxidase-Catalyzed Reduction of Dioxygen to Water: Evidence for Peroxy and Ferryl Intermediates at Room Temperature

Biochemistry (Easton), 1997-01, Vol.36 (3), p.554-565

1997

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N-((8-Hydroxy-5-substituted-quinolin-7-yl)(phenyl)methyl)-2-phenyloxy/amino-acetamide inhibitors of ADAMTS-5 (Aggrecanase-2)

Bioorganic & medicinal chemistry, 2008-12, Vol.18 (24), p.6454-6457

2008

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5-((1 H-Pyrazol-4-yl)methylene)-2-thioxothiazolidin-4-one inhibitors of ADAMTS-5

Bioorganic & medicinal chemistry letters, 2007-03, Vol.17 (5), p.1189-1192

2007

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5'-Phenyl-3'H-spiro[indoline-3,2'-[1,3,4]thiadiazol]-2-one inhibitors of ADAMTS-5 (aggrecanase-2)

Bioorganic & medicinal chemistry letters, 2007-10, Vol.17 (20), p.5630-5633

2007

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Synthesis and evaluation of aryl thioxothiazolidinone inhibitors of ADAMTS-5 (Aggrecanase-2)

Bioorganic & medicinal chemistry letters, 2007-03, Vol.17 (5), p.1185-1188

2007

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Synthesis and biological evaluation of ((4-keto)-phenoxy)methyl biphenyl-4-sulfonamides: A class of potent aggrecanase-1 inhibitors

Bioorganic & medicinal chemistry letters, 2009-05, Vol.19 (9), p.2487-2491

2009

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Continued exploration of biphenylsulfonamide scaffold as a platform for aggrecanase-1 inhibition

Bioorganic & medicinal chemistry letters, 2011-11, Vol.21 (22), p.6800-6803

2011

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Intramolecular Electron Transfer and Conformational Changes in Cytochrome c Oxidase

Biochemistry (Easton), 1995-01, Vol.34 (2), p.496-508

1995

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Time-Resolved Optical Absorption Studies of Intramolecular Electron Transfer in Cytochrome c Oxidase

Biochemistry (Easton), 1994-08, Vol.33 (31), p.9245-9256

1994

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ADAM-TS8, a Novel Metalloprotease of the ADAM-TS Family Located on Mouse Chromosome 9 and Human Chromosome 11

Genomics (San Diego, Calif.), 1999-12, Vol.62 (2), p.312-315

1999

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5′-Phenyl-3′H-spiro[indoline-3,2′-[1,3,4]thiadiazol]-2-one inhibitors of ADAMTS-5 (Aggrecanase-2)

Bioorganic & medicinal chemistry letters, 2007-10, Vol.17 (20), p.5630-5633

2007

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Interleukin 1 (IL-1) Causes Changes in Lateral and Rotational Mobilities of IL-1 Type I Receptors

Biochemistry (Easton), 1999-02, Vol.38 (5), p.1618-1625

1999

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New Transients in the Electron-Transfer Dynamics of Photolyzed Mixed- Valence CO-Cytochrome c Oxidase

Proceedings of the National Academy of Sciences - PNAS, 1992-08, Vol.89 (15), p.6934-6937

1992

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5' -Penyl-3'H -spiro[indoline -3,2-[1,3,4]thiadiazol]-2 -one inhibitors of ADATS-5 (aggrecanase-2)

Bioorganic & medicinal chemistry letters, 2007, Vol.17 (20), p.5630-5633

2007

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Evidence for a band III analogue in the near-infrared absorption spectra of cytochrome c oxidase

Biochemical and biophysical research communications, 1992-04, Vol.184 (2), p.1035-1041

1992

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Evidence for a band III analogue in the near-infrared absorption spectra of cytochrome [formula omitted] oxidase

Biochemical and biophysical research communications, 1992, Vol.184 (2), p.1035-1041

1992

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Investigation of intramolecular electron transfer and oxygen activation in cytochrome c oxidase

Georgiadis, Katy E

1994

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J chain deficiency in human IgM monoclonal antibodies produced by Epstein‐Barr virus‐transformed B lymphocytes

European journal of immunology, 1990-11, Vol.20 (11), p.2505-2508

1990

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Specific, high-affinity bradykinin binding by purified porcine kidney post-proline cleaving enzyme

Biochemical pharmacology, 1987, Vol.36 (1), p.39-49

1987

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Endovascular Thrombectomy for Large Ischemic Stroke Across Ischemic Injury and Penumbra Profiles

JAMA : the journal of the American Medical Association, 2024-03, Vol.331 (9), p.750

2024

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Endovascular Thrombectomy Treatment Effect in Direct vs Transferred Patients With Large Ischemic Strokes: A Prespecified Analysis of the SELECT2 Trial

JAMA neurology, 2024-04, Vol.81 (4), p.327

2024

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Synthesis and biological evaluation of biphenylsulfonamide carboxylate aggrecanase-1 inhibitors

Bioorganic & medicinal chemistry letters, 2006-01, Vol.16 (2), p.311-316

2006

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ADAMTS-8 exhibits aggrecanase activity and is expressed in human articular cartilage

Discovery of Novel, Potent Inhibitors of Hydroxy Acid Oxidase 1 (HAO1) Using DNA-Encoded Chemical Library Screening

Mechanism of Cytochrome c Oxidase-Catalyzed Reduction of Dioxygen to Water: Evidence for Peroxy and Ferryl Intermediates at Room Temperature

N-((8-Hydroxy-5-substituted-quinolin-7-yl)(phenyl)methyl)-2-phenyloxy/amino-acetamide inhibitors of ADAMTS-5 (Aggrecanase-2)

5-((1 H-Pyrazol-4-yl)methylene)-2-thioxothiazolidin-4-one inhibitors of ADAMTS-5

5'-Phenyl-3'H-spiro[indoline-3,2'-[1,3,4]thiadiazol]-2-one inhibitors of ADAMTS-5 (aggrecanase-2)

Synthesis and evaluation of aryl thioxothiazolidinone inhibitors of ADAMTS-5 (Aggrecanase-2)

Synthesis and biological evaluation of ((4-keto)-phenoxy)methyl biphenyl-4-sulfonamides: A class of potent aggrecanase-1 inhibitors

Continued exploration of biphenylsulfonamide scaffold as a platform for aggrecanase-1 inhibition

Intramolecular Electron Transfer and Conformational Changes in Cytochrome c Oxidase

Time-Resolved Optical Absorption Studies of Intramolecular Electron Transfer in Cytochrome c Oxidase

ADAM-TS8, a Novel Metalloprotease of the ADAM-TS Family Located on Mouse Chromosome 9 and Human Chromosome 11

5′-Phenyl-3′H-spiro[indoline-3,2′-[1,3,4]thiadiazol]-2-one inhibitors of ADAMTS-5 (Aggrecanase-2)

Interleukin 1 (IL-1) Causes Changes in Lateral and Rotational Mobilities of IL-1 Type I Receptors

New Transients in the Electron-Transfer Dynamics of Photolyzed Mixed- Valence CO-Cytochrome c Oxidase

5' -Penyl-3'H -spiro[indoline -3,2-[1,3,4]thiadiazol]-2 -one inhibitors of ADATS-5 (aggrecanase-2)

Evidence for a band III analogue in the near-infrared absorption spectra of cytochrome c oxidase

Evidence for a band III analogue in the near-infrared absorption spectra of cytochrome [formula omitted] oxidase

Investigation of intramolecular electron transfer and oxygen activation in cytochrome c oxidase

J chain deficiency in human IgM monoclonal antibodies produced by Epstein‐Barr virus‐transformed B lymphocytes

Specific, high-affinity bradykinin binding by purified porcine kidney post-proline cleaving enzyme

Endovascular Thrombectomy for Large Ischemic Stroke Across Ischemic Injury and Penumbra Profiles

Endovascular Thrombectomy Treatment Effect in Direct vs Transferred Patients With Large Ischemic Strokes: A Prespecified Analysis of the SELECT2 Trial

Synthesis and biological evaluation of biphenylsulfonamide carboxylate aggrecanase-1 inhibitors

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