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Central role of the BK channel in urinary bladder smooth muscle physiology and pathophysiology

American journal of physiology. Regulatory, integrative and comparative physiology, 2014-09, Vol.307 (6), p.R571-R584

Petkov, Georgi V

2014

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Role of potassium ion channels in detrusor smooth muscle function and dysfunction

Nature reviews. Urology, 2012-01, Vol.9 (1), p.30-40

Petkov, Georgi V

2012

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Detrusor Smooth Muscle KV7 Channels: Emerging New Regulators of Urinary Bladder Function

Frontiers in physiology, 2020-09, Vol.11, p.1004-1004

2020

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Molecular expression and pharmacological evidence for a functional role of kv7 channel subtypes in Guinea pig urinary bladder smooth muscle

PloS one, 2013-09, Vol.8 (9), p.e75875-e75875

2013

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Large-conductance voltage- and Ca2+-activated K+ channels regulate human detrusor smooth muscle function

American Journal of Physiology: Cell Physiology, 2011-10, Vol.301 (4), p.C903-C912

2011

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Novel mechanism of hydrogen sulfide-induced guinea pig urinary bladder smooth muscle contraction: role of BK channels and cholinergic neurotransmission

American Journal of Physiology: Cell Physiology, 2015-07, Vol.309 (2), p.C107-C116

2015

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Urinary bladder smooth muscle ion channels: expression, function, and regulation in health and disease

American journal of physiology. Renal physiology, 2020-08, Vol.319 (2), p.F257-F283

2020

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Testosterone decreases urinary bladder smooth muscle excitability via novel signaling mechanism involving direct activation of the BK channels

American journal of physiology. Renal physiology, 2016-12, Vol.311 (6), p.F1253-F1259

2016

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Regulation of Guinea Pig Detrusor Smooth Muscle Excitability by 17β-Estradiol: The Role of the Large Conductance Voltage- and Ca2+-Activated K+ Channels

PloS one, 2015-11, Vol.10 (11), p.e0141950-e0141950

2015

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BK channel-mediated relaxation of urinary bladder smooth muscle: a novel paradigm for phosphodiesterase type 4 regulation of bladder function

The Journal of pharmacology and experimental therapeutics, 2014-04, Vol.349 (1), p.56-65

2014

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Differential effects of TRPM4 channel inhibitors on Guinea pig urinary bladder smooth muscle excitability and contractility: Novel 4‐chloro‐2‐[2‐(2‐chloro‐phenoxy)‐acetylamino]‐benzoic acid (CBA) versus classical 9‐phenanthrol

Pharmacology research & perspectives, 2022-08, Vol.10 (4), p.e00982-n/a

2022

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Identification of Large Conductance Calcium Activated Potassium Channel Accessory β4 Subunit in Rat and Mouse Bladder Smooth Muscle

The Journal of urology, 2009-07, Vol.182 (1), p.374-381

2009

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Neurogenic detrusor overactivity is associated with decreased expression and function of the large conductance voltage- and Ca(2+)-activated K(+) channels

PloS one, 2013, Vol.8 (7), p.e68052-e68052

2013

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Novel regulatory mechanism in human urinary bladder: central role of transient receptor potential melastatin 4 channels in detrusor smooth muscle function

American Journal of Physiology: Cell Physiology, 2016-04, Vol.310 (7), p.C600-C611

2016

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Suppression of human detrusor smooth muscle excitability and contractility via pharmacological activation of large conductance Ca2+-activated K+ channels

American Journal of Physiology: Cell Physiology, 2012-06, Vol.302 (11), p.C1632-C1641

2012

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Age‐dependent decrease in TRPM4 channel expression but not trafficking alters urinary bladder smooth muscle contractility

Physiological reports, 2021-02, Vol.9 (4), p.e14754-n/a

2021

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Inhibition of phosphodiesterases relaxes detrusor smooth muscle via activation of the large-conductance voltage- and Ca²⁺-activated K⁺ channel

American Journal of Physiology: Cell Physiology, 2012-05, Vol.302 (9), p.C1361-C1370

2012

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Novel role for the transient potential receptor melastatin 4 channel in guinea pig detrusor smooth muscle physiology

American Journal of Physiology: Cell Physiology, 2013-03, Vol.304 (5), p.C467-C477

2013

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NS309 decreases rat detrusor smooth muscle membrane potential and phasic contractions by activating SK3 channels

British journal of pharmacology, 2013-04, Vol.168 (7), p.1611-1625

2013

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TRPM4 channel: a new player in urinary bladder smooth muscle function in rats

American journal of physiology. Renal physiology, 2013-04, Vol.304 (7), p.F918-F929

2013

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SK channel-selective opening by SKA-31 induces hyperpolarization and decreases contractility in human urinary bladder smooth muscle

American journal of physiology. Regulatory, integrative and comparative physiology, 2013-01, Vol.304 (2), p.R155-R163

2013

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Prostaglandin E2 excitatory effects on guinea pig urinary bladder smooth muscle: a novel regulatory mechanism mediated by large-conductance voltage- and Ca2+-activated K+ channels

European journal of pharmacology, 2014-09, Vol.738, p.179-185

2014

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Nongenomic modulation of the large conductance voltage‐ and Ca2+‐activated K+ channels by estrogen: A novel regulatory mechanism in human detrusor smooth muscle

Physiological reports, 2017-07, Vol.5 (14), p.n/a

2017

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Extracellular pH and intracellular phosphatidylinositol 4,5-bisphosphate control Cl - currents in guinea pig detrusor smooth muscle cells

American Journal of Physiology: Cell Physiology, 2019-12, Vol.317 (6), p.C1268-C1277

2019

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Voltage-gated K(+) channels sensitive to stromatoxin-1 regulate myogenic and neurogenic contractions of rat urinary bladder smooth muscle

American journal of physiology. Regulatory, integrative and comparative physiology, 2010-07, Vol.299 (1), p.R177-R184

2010

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Central role of the BK channel in urinary bladder smooth muscle physiology and pathophysiology

Role of potassium ion channels in detrusor smooth muscle function and dysfunction

Detrusor Smooth Muscle KV7 Channels: Emerging New Regulators of Urinary Bladder Function

Molecular expression and pharmacological evidence for a functional role of kv7 channel subtypes in Guinea pig urinary bladder smooth muscle

Large-conductance voltage- and Ca2+-activated K+ channels regulate human detrusor smooth muscle function

Novel mechanism of hydrogen sulfide-induced guinea pig urinary bladder smooth muscle contraction: role of BK channels and cholinergic neurotransmission

Urinary bladder smooth muscle ion channels: expression, function, and regulation in health and disease

Testosterone decreases urinary bladder smooth muscle excitability via novel signaling mechanism involving direct activation of the BK channels

Regulation of Guinea Pig Detrusor Smooth Muscle Excitability by 17β-Estradiol: The Role of the Large Conductance Voltage- and Ca2+-Activated K+ Channels

BK channel-mediated relaxation of urinary bladder smooth muscle: a novel paradigm for phosphodiesterase type 4 regulation of bladder function

Differential effects of TRPM4 channel inhibitors on Guinea pig urinary bladder smooth muscle excitability and contractility: Novel 4‐chloro‐2‐[2‐(2‐chloro‐phenoxy)‐acetylamino]‐benzoic acid (CBA) versus classical 9‐phenanthrol

Identification of Large Conductance Calcium Activated Potassium Channel Accessory β4 Subunit in Rat and Mouse Bladder Smooth Muscle

Neurogenic detrusor overactivity is associated with decreased expression and function of the large conductance voltage- and Ca(2+)-activated K(+) channels

Novel regulatory mechanism in human urinary bladder: central role of transient receptor potential melastatin 4 channels in detrusor smooth muscle function

Suppression of human detrusor smooth muscle excitability and contractility via pharmacological activation of large conductance Ca2+-activated K+ channels

Age‐dependent decrease in TRPM4 channel expression but not trafficking alters urinary bladder smooth muscle contractility

Inhibition of phosphodiesterases relaxes detrusor smooth muscle via activation of the large-conductance voltage- and Ca²⁺-activated K⁺ channel

Novel role for the transient potential receptor melastatin 4 channel in guinea pig detrusor smooth muscle physiology

NS309 decreases rat detrusor smooth muscle membrane potential and phasic contractions by activating SK3 channels

TRPM4 channel: a new player in urinary bladder smooth muscle function in rats

SK channel-selective opening by SKA-31 induces hyperpolarization and decreases contractility in human urinary bladder smooth muscle

Prostaglandin E2 excitatory effects on guinea pig urinary bladder smooth muscle: a novel regulatory mechanism mediated by large-conductance voltage- and Ca2+-activated K+ channels

Nongenomic modulation of the large conductance voltage‐ and Ca2+‐activated K+ channels by estrogen: A novel regulatory mechanism in human detrusor smooth muscle

Extracellular pH and intracellular phosphatidylinositol 4,5-bisphosphate control Cl - currents in guinea pig detrusor smooth muscle cells

Voltage-gated K(+) channels sensitive to stromatoxin-1 regulate myogenic and neurogenic contractions of rat urinary bladder smooth muscle

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