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Advances in computational and experimental approaches for deciphering transcriptional regulatory networks: Understanding the roles of cis-regulatory elements is essential, and recent research utilizing MPRAs, STARR-seq, CRISPR-Cas9, and machine learning has yielded valuable insights

BioEssays, 2024-07, Vol.46 (7), p.e2300210

2024

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Alternative splicing modulation by G-quadruplexes

Nature communications, 2022-05, Vol.13 (1), p.2404-2404, Article 2404

2022

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Deletion of CTCF sites in the SHH locus alters enhancer-promoter interactions and leads to acheiropodia

Nature communications, 2021-04, Vol.12 (1), p.2282-12, Article 2282

2021

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lentiMPRA and MPRAflow for high-throughput functional characterization of gene regulatory elements

Nature protocols, 2020-08, Vol.15 (8), p.2387-2412

2020

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Transcription-coupled repair and mismatch repair contribute towards preserving genome integrity at mononucleotide repeat tracts

Nature communications, 2020-04, Vol.11 (1), p.1980-9, Article 1980

2020

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EMT Factors and Metabolic Pathways in Cancer

Frontiers in oncology, 2020-04, Vol.10, p.499-499

2020

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Noncanonical secondary structures arising from non-B DNA motifs are determinants of mutagenesis

Genome research, 2018-09, Vol.28 (9), p.1264

2018

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Editorial: Mutational signatures and immune response in cancer

Frontiers in genetics, 2023-05, Vol.14, p.1215326-1215326

2023

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Distinct genomic features across cytolytic subgroups in skin melanoma

Cancer Immunology, Immunotherapy, 2021-11, Vol.70 (11), p.3137-3154

2021

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The Efficacy of Tumor Mutation Burden as a Biomarker of Response to Immune Checkpoint Inhibitors

International journal of molecular sciences, 2023-04, Vol.24 (7), p.6710

2023

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Absent from DNA and protein: genomic characterization of nullomers and nullpeptides across functional categories and evolution

Genome Biology, 2021-08, Vol.22 (1), p.245-245, Article 245

2021

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High-throughput techniques enable advances in the roles of DNA and RNA secondary structures in transcriptional and post-transcriptional gene regulation

Genome Biology, 2022-07, Vol.23 (1), p.1-159, Article 159

2022

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Transcription factor binding site orientation and order are major drivers of gene regulatory activity

Nature communications, 2023-04, Vol.14 (1), p.2333-2333, Article 2333

2023

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Deregulated Gene Expression Profiles and Regulatory Networks in Adult and Pediatric RUNX1/RUNX1T1-Positive AML Patients

Cancers, 2023-03, Vol.15 (6), p.1795

2023

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A Multi-Omics Analysis of an Exhausted T Cells’ Molecular Signature in Pan-Cancer

Journal of personalized medicine, 2024-07, Vol.14 (7), p.765

2024

Volltextzugriff (PDF)

Author Correction: High-throughput techniques enable advances in the roles of DNA and RNA secondary structures in transcriptional and post-transcriptional gene regulation

Genome Biology, 2022-07, Vol.23 (1), p.1-164, Article 164

2022

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Strand asymmetries across genomic processes

Computational and structural biotechnology journal, 2023-01, Vol.21, p.2036-2047

2023

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Asymmetron: a toolkit for the identification of strand asymmetry patterns in biological sequences

Nucleic acids research, 2021-01, Vol.49 (1), p.e4

2021

Volltextzugriff (PDF)

Frequentmers - a novel way to look at metagenomic next generation sequencing data and an application in detecting liver cirrhosis

BMC genomics, 2023-12, Vol.24 (1), p.768-768, Article 768

2023

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Approaches of dengue control: vaccine strategies and future aspects

Frontiers in immunology, 2024-02, Vol.15, p.1362780-1362780

2024

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MicroExonator enables systematic discovery and quantification of microexons across mouse embryonic development

Genome Biology, 2021-01, Vol.22 (1), p.43-43, Article 43

2021

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Integrative single-cell characterization of a frugivorous and an insectivorous bat kidney and pancreas

Nature communications, 2024-01, Vol.15 (1), p.12-12, Article 12

2024

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Author Correction: Integrative single-cell characterization of a frugivorous and an insectivorous bat kidney and pancreas

Nature communications, 2024-02, Vol.15 (1), p.1777-1777, Article 1777

2024

Volltextzugriff (PDF)

Transcriptomic profiling of the response to excess iodide in Keap1 hypomorphic mice reveals new gene-environment interactions in thyroid homeostasis

Redox biology, 2024-02, Vol.69, p.102978-102978, Article 102978

2024

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Advances in computational and experimental approaches for deciphering transcriptional regulatory networks: Understanding the roles of cis-regulatory elements is essential, and recent research utilizing MPRAs, STARR-seq, CRISPR-Cas9, and machine learning has yielded valuable insights

Alternative splicing modulation by G-quadruplexes

Deletion of CTCF sites in the SHH locus alters enhancer-promoter interactions and leads to acheiropodia

lentiMPRA and MPRAflow for high-throughput functional characterization of gene regulatory elements

Transcription-coupled repair and mismatch repair contribute towards preserving genome integrity at mononucleotide repeat tracts

EMT Factors and Metabolic Pathways in Cancer

Noncanonical secondary structures arising from non-B DNA motifs are determinants of mutagenesis

Editorial: Mutational signatures and immune response in cancer

Distinct genomic features across cytolytic subgroups in skin melanoma

The Efficacy of Tumor Mutation Burden as a Biomarker of Response to Immune Checkpoint Inhibitors

Characterizing Mutational Signatures in Human Cancer Cell Lines Reveals Episodic APOBEC Mutagenesis

Absent from DNA and protein: genomic characterization of nullomers and nullpeptides across functional categories and evolution

High-throughput techniques enable advances in the roles of DNA and RNA secondary structures in transcriptional and post-transcriptional gene regulation

Transcription factor binding site orientation and order are major drivers of gene regulatory activity

Deregulated Gene Expression Profiles and Regulatory Networks in Adult and Pediatric RUNX1/RUNX1T1-Positive AML Patients

A Multi-Omics Analysis of an Exhausted T Cells’ Molecular Signature in Pan-Cancer

Author Correction: High-throughput techniques enable advances in the roles of DNA and RNA secondary structures in transcriptional and post-transcriptional gene regulation

Strand asymmetries across genomic processes

Asymmetron: a toolkit for the identification of strand asymmetry patterns in biological sequences

Frequentmers - a novel way to look at metagenomic next generation sequencing data and an application in detecting liver cirrhosis

Approaches of dengue control: vaccine strategies and future aspects

MicroExonator enables systematic discovery and quantification of microexons across mouse embryonic development

Integrative single-cell characterization of a frugivorous and an insectivorous bat kidney and pancreas

Author Correction: Integrative single-cell characterization of a frugivorous and an insectivorous bat kidney and pancreas

Transcriptomic profiling of the response to excess iodide in Keap1 hypomorphic mice reveals new gene-environment interactions in thyroid homeostasis

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