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Using available in vitro metabolite identification and time course kinetics for β-chloroprene and its metabolite, (1-chloroethenyl) oxirane, to include reactive oxidative metabolites and glutathione depletion in a PBPK model for β-chloroprene

Frontiers in pharmacology, 2023-08, Vol.14, p.1223808-1223808

2023

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Concentration- and Time-dependent Genomic Changes in the Mouse Urinary Bladder Following Exposure to Arsenate in Drinking Water for up to 12 Weeks

Toxicological sciences, 2011-10, Vol.123 (2), p.421-432

2011

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Use of mode of action data to inform a dose–response assessment for bladder cancer following exposure to inorganic arsenic

Toxicology in vitro, 2014-10, Vol.28 (7), p.1196-1205

2014

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A constrained maximum likelihood approach to evaluate the impact of dose metric on cancer risk assessment: Application to β-chloroprene

Regulatory toxicology and pharmacology, 2014-10, Vol.70 (1), p.203-213

2014

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Assessing children's exposure to manganese in drinking water using a PBPK model

Toxicology and applied pharmacology, 2019-10, Vol.380, p.114695, Article 114695

2019

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Response to "letter concerning: Clewell (2019) incorporation of in vitro metabolism data and physiologically based pharmacokinetic modeling in a risk assessment for chloroprene." (UIHT-2020-0053)

Inhalation toxicology, 2020-08, Vol.32 (9-10), p.369-371

2020

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Genetic Polymorphisms in Assessing Interindividual Variability in Delivered Dose

Regulatory toxicology and pharmacology, 2002-04, Vol.35 (2), p.177-197

2002

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Considering pharmacokinetic and mechanistic information in cancer risk assessments for environmental contaminants: Examples with vinyl chloride and trichloroethylene

Chemosphere (Oxford), 1995-07, Vol.31 (1), p.2561-2578

1995

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Development of a Physiologically Based Pharmacokinetic Model of Trichloroethylene and Its Metabolites for Use in Risk Assessment

Environmental health perspectives, 2000-05, Vol.108 (Suppl 2), p.283-305

2000

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Comparison of cancer risk estimates for vinyl chloride using animal and human data with a PBPK model

The Science of the total environment, 2001-07, Vol.274 (1), p.37-66

2001

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An Approach for the Quantitative Consideration of Genetic Polymorphism Data in Chemical Risk Assessment: Examples with Warfarin and Parathion

Toxicological sciences, 2002-11, Vol.70 (1), p.120-139

2002

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Development of a physiologically based pharmacokinetic model of isopropanol and its metabolite acetone

Toxicological sciences, 2001-10, Vol.63 (2), p.160-172

2001

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Evaluation of the Uncertainty in an Oral Reference Dose for Methylmercury Due to Interindividual Variability in Pharmacokinetics

Risk analysis, 1999-08, Vol.19 (4), p.547-558

1999

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Long-term feeding of high zinc sulfate diets to lactating and gestating dairy cows

Journal of dairy science, 1989-06, Vol.72 (6), p.1499-1508

1989

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INVESTIGATION OF THE POTENTIAL IMPACT OF BENCHMARK DOSE AND PHARMACOKINETIC MODELING IN NONCANCER RISK ASSESSMENT

Journal of toxicology and environmental health, 1997-12, Vol.52 (6), p.475-515

1997

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Effects of High Dietary Iron as Ferrous Carbonate on Performance of Young Dairy Calves

Journal of dairy science, 1991-06, Vol.74 (6), p.1963-1967

1991

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Zinc absorption, metabolism, and endogenous excretion in zinc-deficient and normal calves over an extended time

Journal of dairy science, 1991-10, Vol.74 (10), p.3535-3543

1991

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Evaluation of the Potential Impact of Age- and Gender-Specific Pharmacokinetic Differences on Tissue Dosimetry

Toxicological sciences, 2004-06, Vol.79 (2), p.381-393

2004

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Influence of a wide range of calcium intakes on tissue distribution of macroelements and microelements in dairy calves

Journal of dairy science, 1988-05, Vol.71 (5), p.1295-1300

1988

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A HYBRID COMPUTATIONAL FLUID DYNAMICS AND PHYSIOLOGICALLY BASED PHARMACOKINETIC MODEL FOR COMPARISON OF PREDICTED TISSUE CONCENTRATIONS OF ACRYLIC ACID AND OTHER VAPORS IN THE RAT AND HUMAN NASAL CAVITIES FOLLOWING INHALATION EXPOSURE

Inhalation toxicology, 2001-05, Vol.13 (5), p.359-376

2001

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Determination of a site-specific reference dose for methylmercury for fish-eating populations

Toxicology and industrial health, 2000-11, Vol.16 (9-10), p.335-438

2000

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Bioavailability of phosphorus from defluorinated and dicalcium phosphates and phosphorus requirement of calves

Journal of dairy science, 1987-09, Vol.70 (9), p.1885-1892

1987

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Influence of high dietary iron as ferrous carbonate and ferrous sulfate on iron metabolism in young calves

Journal of dairy science, 1985-10, Vol.68 (10), p.2621-2628

1985

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Influence of high dietary lead on selenium metabolism in dairy calves

Journal of dairy science, 1987-03, Vol.70 (3), p.645-652

1987

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Effects of varying the amounts of dietary calcium on selenium metabolism in dairy calves

Journal of dairy science, 1987-04, Vol.70 (4), p.831-836

1987

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Using available in vitro metabolite identification and time course kinetics for β-chloroprene and its metabolite, (1-chloroethenyl) oxirane, to include reactive oxidative metabolites and glutathione depletion in a PBPK model for β-chloroprene

Concentration- and Time-dependent Genomic Changes in the Mouse Urinary Bladder Following Exposure to Arsenate in Drinking Water for up to 12 Weeks

Use of mode of action data to inform a dose–response assessment for bladder cancer following exposure to inorganic arsenic

A constrained maximum likelihood approach to evaluate the impact of dose metric on cancer risk assessment: Application to β-chloroprene

Assessing children's exposure to manganese in drinking water using a PBPK model

Response to "letter concerning: Clewell (2019) incorporation of in vitro metabolism data and physiologically based pharmacokinetic modeling in a risk assessment for chloroprene." (UIHT-2020-0053)

Genetic Polymorphisms in Assessing Interindividual Variability in Delivered Dose

Considering pharmacokinetic and mechanistic information in cancer risk assessments for environmental contaminants: Examples with vinyl chloride and trichloroethylene

Development of a Physiologically Based Pharmacokinetic Model of Trichloroethylene and Its Metabolites for Use in Risk Assessment

Comparison of cancer risk estimates for vinyl chloride using animal and human data with a PBPK model

An Approach for the Quantitative Consideration of Genetic Polymorphism Data in Chemical Risk Assessment: Examples with Warfarin and Parathion

Development of a physiologically based pharmacokinetic model of isopropanol and its metabolite acetone

Evaluation of the Uncertainty in an Oral Reference Dose for Methylmercury Due to Interindividual Variability in Pharmacokinetics

Long-term feeding of high zinc sulfate diets to lactating and gestating dairy cows

INVESTIGATION OF THE POTENTIAL IMPACT OF BENCHMARK DOSE AND PHARMACOKINETIC MODELING IN NONCANCER RISK ASSESSMENT

Effects of High Dietary Iron as Ferrous Carbonate on Performance of Young Dairy Calves

Zinc absorption, metabolism, and endogenous excretion in zinc-deficient and normal calves over an extended time

Evaluation of the Potential Impact of Age- and Gender-Specific Pharmacokinetic Differences on Tissue Dosimetry

Influence of a wide range of calcium intakes on tissue distribution of macroelements and microelements in dairy calves

A HYBRID COMPUTATIONAL FLUID DYNAMICS AND PHYSIOLOGICALLY BASED PHARMACOKINETIC MODEL FOR COMPARISON OF PREDICTED TISSUE CONCENTRATIONS OF ACRYLIC ACID AND OTHER VAPORS IN THE RAT AND HUMAN NASAL CAVITIES FOLLOWING INHALATION EXPOSURE

Determination of a site-specific reference dose for methylmercury for fish-eating populations

Bioavailability of phosphorus from defluorinated and dicalcium phosphates and phosphorus requirement of calves

Influence of high dietary iron as ferrous carbonate and ferrous sulfate on iron metabolism in young calves

Influence of high dietary lead on selenium metabolism in dairy calves

Effects of varying the amounts of dietary calcium on selenium metabolism in dairy calves

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