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Novel 1,5-Diphenylpyrazole Nonnucleoside HIV-1 Reverse Transcriptase Inhibitors with Enhanced Activity versus the Delavirdine-Resistant P236L Mutant: Lead Identification and SAR of 3- and 4-Substituted Derivatives

Journal of medicinal chemistry, 2000-03, Vol.43 (5), p.1034-1040

2000

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Substituent Effects on the Antibacterial Activity of Nitrogen−Carbon-Linked (Azolylphenyl)oxazolidinones with Expanded Activity Against the Fastidious Gram-Negative Organisms Haemophilus influenzae and Moraxella catarrhalis

Journal of medicinal chemistry, 2000-03, Vol.43 (5), p.953-970

2000

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The effect of remote chirality on the antibacterial activity of indolinyl, tetrahydroquinolyl and dihydrobenzoxazinyl oxazolidinones

Bioorganic & medicinal chemistry letters, 2003-12, Vol.13 (23), p.4235-4239

2003

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Recent progress with oxazolidinone antibacterial agents

Expert opinion on therapeutic patents, 2000-09, Vol.10 (9), p.1405-1414

Genin, Michael J

2000

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Design, synthesis, and conformational analysis of a novel spiro-bicyclic system as a type II .beta.-turn peptidomimetic

Journal of the American Chemical Society, 1992-11, Vol.114 (23), p.8778-8783

1992

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Bis(heteroaryl)piperazine (BHAP) reverse transcriptase inhibitors: structure-activity relationships of novel substituted indole analogues and the identification of 1-[(5-methanesulfonamido-1H-indol-2-yl)-carbonyl]-4-[3- [(1-methylethyl)amino]-pyridinyl]piperazine monomethanesulfonate (U-90152S), a second-generation clinical candidate

Journal of medicinal chemistry, 1993-05, Vol.36 (10), p.1505-1508

1993

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Carbon–carbon-linked (pyrazolylphenyl)oxazolidinones with antibacterial activity against multiple drug resistant gram-positive and fastidious gram-negative bacteria

Bioorganic & medicinal chemistry, 2001-12, Vol.9 (12), p.3243-3253

2001

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Nitrogen−Carbon-Linked (Azolylphenyl)oxazolidinones with Potent Antibacterial Activity Against the Fastidious Gram-Negative Organisms Haemophilus influenzae and Moraxella catarrhalis

Journal of medicinal chemistry, 1998-12, Vol.41 (26), p.5144-5147

1998

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Dopamine receptor modulation by a highly rigid spiro bicyclic peptidomimetic of Pro-Leu-Gly-NH2

Journal of medicinal chemistry, 1993-10, Vol.36 (22), p.3481-3483

1993

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Synthesis and Bioactivity of Novel Bis(heteroaryl)piperazine (BHAP) Reverse Transcriptase Inhibitors: Structure−Activity Relationships and Increased Metabolic Stability of Novel Substituted Pyridine Analogs

Journal of medicinal chemistry, 1996-12, Vol.39 (26), p.5267-5275

1996

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Synthesis and Structure−Activity Relationships of the (Alkylamino)piperidine-Containing BHAP Class of Non-Nucleoside Reverse Transcriptase Inhibitors: Effect of 3-Alkylpyridine Ring Substitution

Journal of medicinal chemistry, 1999-10, Vol.42 (20), p.4140-4149

1999

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Synthesis and crystal structure of a peptidomimetic containing the (R)-4.4-spiro lactam type-II .beta.-turn mimic

Journal of organic chemistry, 1993-04, Vol.58 (8), p.2334-2337

1993

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An improved method of oxazolidinone hydrolysis in the asymmetric synthesis of α-alkylprolines

Tetrahedron letters, 1994-07, Vol.35 (28), p.4967-4968

1994

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Design and synthesis of a conformationally constrained analog of the bis(heteroaryl)piperazine (BHAP) HIV-1 reverse transcriptase inhibitor atevirdine

Bioorganic & medicinal chemistry letters, 1995-08, Vol.5 (16), p.1875-1880

1995

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Dopamine receptor modulation by a highly rigid spiro bicyclic peptidomimetic of Pro-Leu-Gly-NH sub(2)

Journal of medicinal chemistry, 1993-01, Vol.36 (22), p.3481-3483

1993

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A novel method for the t-butylation of aromatic amines

Tetrahedron letters, 1993-07, Vol.34 (27), p.4301-4304

1993

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Application of conformationally restricted peptidomimetics to modeling the bound conformation of peptide antagonists with the IL-1 receptor

International journal of peptide research and therapeutics, 1998-05, Vol.5 (2-3), p.93-100

1998

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Bis(heteroaryl)piperazine (BHAP) reverse transcriptase inhibitors: Structure-activity relationships of novel substituted indole analogues and the identification of 1-((5-methanesulfonamido-1H-indol-2-yl)-carbonyl)-4-(3-((1-methyle thyl)amino)-pyridinyl)piperazine monomethanesulfonate (U-90152S), a second-generation clinical candidate

Journal of medicinal chemistry, 1993-01, Vol.36 (10), p.1505-1508

1993

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Patchiness and depth-keeping of copepods in response to simulated frontal flows

Marine ecology. Progress series (Halstenbek), 2015-11, Vol.539, p.65-76

2015

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Comparison of structure and properties of femtosecond and nanosecond laser-structured silicon

Applied physics letters, 2004-03, Vol.84 (11), p.1850-1852

2004

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Interferon regulatory factors: the next generation

Gene, 1999-09, Vol.237 (1), p.1-14

1999

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Histological Detection of Minimal Metastatic Involvement in Axillary Sentinel Nodes: A Rational Basis for a Sensitive Methodology Usable in Daily Practice

Modern pathology, 2002-06, Vol.15 (6), p.641-646

2002

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Homozygous deletion of the death receptor DR4 gene in a nasopharyngeal cancer cell line is associated with TRAIL resistance

International journal of oncology, 2000-05, Vol.16 (5), p.917

2000

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Analytical and Numerical Modeling of Surface Morphologies in Thin Films

MRS proceedings, 1995, Vol.389, Article 83

Genin, François Y.

1995

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Musculoskeletal tumors: follow-up with MR imaging after treatment with surgery and radiation therapy

Radiology, 1987-07, Vol.164 (1), p.243-245

1987

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Novel 1,5-Diphenylpyrazole Nonnucleoside HIV-1 Reverse Transcriptase Inhibitors with Enhanced Activity versus the Delavirdine-Resistant P236L Mutant: Lead Identification and SAR of 3- and 4-Substituted Derivatives

Substituent Effects on the Antibacterial Activity of Nitrogen−Carbon-Linked (Azolylphenyl)oxazolidinones with Expanded Activity Against the Fastidious Gram-Negative Organisms Haemophilus influenzae and Moraxella catarrhalis

The effect of remote chirality on the antibacterial activity of indolinyl, tetrahydroquinolyl and dihydrobenzoxazinyl oxazolidinones

Recent progress with oxazolidinone antibacterial agents

Design, synthesis, and conformational analysis of a novel spiro-bicyclic system as a type II .beta.-turn peptidomimetic

Carbon–carbon-linked (pyrazolylphenyl)oxazolidinones with antibacterial activity against multiple drug resistant gram-positive and fastidious gram-negative bacteria

Nitrogen−Carbon-Linked (Azolylphenyl)oxazolidinones with Potent Antibacterial Activity Against the Fastidious Gram-Negative Organisms Haemophilus influenzae and Moraxella catarrhalis

Dopamine receptor modulation by a highly rigid spiro bicyclic peptidomimetic of Pro-Leu-Gly-NH2

Synthesis and Bioactivity of Novel Bis(heteroaryl)piperazine (BHAP) Reverse Transcriptase Inhibitors: Structure−Activity Relationships and Increased Metabolic Stability of Novel Substituted Pyridine Analogs

Synthesis and Structure−Activity Relationships of the (Alkylamino)piperidine-Containing BHAP Class of Non-Nucleoside Reverse Transcriptase Inhibitors: Effect of 3-Alkylpyridine Ring Substitution

Synthesis and crystal structure of a peptidomimetic containing the (R)-4.4-spiro lactam type-II .beta.-turn mimic

An improved method of oxazolidinone hydrolysis in the asymmetric synthesis of α-alkylprolines

Design and synthesis of a conformationally constrained analog of the bis(heteroaryl)piperazine (BHAP) HIV-1 reverse transcriptase inhibitor atevirdine

Dopamine receptor modulation by a highly rigid spiro bicyclic peptidomimetic of Pro-Leu-Gly-NH sub(2)

A novel method for the t-butylation of aromatic amines

Application of conformationally restricted peptidomimetics to modeling the bound conformation of peptide antagonists with the IL-1 receptor

Patchiness and depth-keeping of copepods in response to simulated frontal flows

Comparison of structure and properties of femtosecond and nanosecond laser-structured silicon

Interferon regulatory factors: the next generation

Histological Detection of Minimal Metastatic Involvement in Axillary Sentinel Nodes: A Rational Basis for a Sensitive Methodology Usable in Daily Practice

Homozygous deletion of the death receptor DR4 gene in a nasopharyngeal cancer cell line is associated with TRAIL resistance

Analytical and Numerical Modeling of Surface Morphologies in Thin Films

Musculoskeletal tumors: follow-up with MR imaging after treatment with surgery and radiation therapy

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