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Embracing proteins: structural themes in aptamer–protein complexes

Current opinion in structural biology, 2016-02, Vol.36, p.122-132

2016

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Nucleic Acid Ligands With Protein-like Side Chains: Modified Aptamers and Their Use as Diagnostic and Therapeutic Agents

Molecular therapy. Nucleic acids, 2014-10, Vol.3 (10), p.e201-e201, Article e201

2014

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Structural basis for IL-1α recognition by a modified DNA aptamer that specifically inhibits IL-1α signaling

Nature communications, 2017-10, Vol.8 (1), p.810-13, Article 810

2017

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Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets

Proceedings of the National Academy of Sciences - PNAS, 2012-12, Vol.109 (49), p.19971-19976

2012

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Broadly neutralizing aptamers to SARS-CoV-2: A diverse panel of modified DNA antiviral agents

Molecular therapy. Nucleic acids, 2023-03, Vol.31, p.370-382

2023

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Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor

Structure (London), 2015-07, Vol.23 (7), p.1293-1304

2015

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Telomere capping proteins are structurally related to RPA with an additional telomere-specific domain

Proceedings of the National Academy of Sciences - PNAS, 2009-11, Vol.106 (46), p.19298-19303

2009

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Evolving A RIG-I Antagonist: A Modified DNA Aptamer Mimics Viral RNA

Journal of molecular biology, 2021-10, Vol.433 (21), p.167227-167227, Article 167227

2021

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Modified nucleotides may have enhanced early RNA catalysis

Proceedings of the National Academy of Sciences - PNAS, 2020-04, Vol.117 (15), p.8236-8242

2020

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Crystal Structure of Interleukin-6 in Complex with a Modified Nucleic Acid Ligand

The Journal of biological chemistry, 2014-03, Vol.289 (12), p.8720-8734

2014

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Modified aptamers as reagents to characterize recombinant human erythropoietin products

Scientific reports, 2020-10, Vol.10 (1), p.18593, Article 18593

2020

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Sequence-Specific Binding to Telomeric DNA Is Not a Conserved Property of the Cdc13 DNA Binding Domain

Biochemistry (Easton), 2011-07, Vol.50 (29), p.6289-6291

2011

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Thermodynamic Linkage in the GrpE Nucleotide Exchange Factor, a Molecular Thermosensor

Biochemistry (Easton), 2003-08, Vol.42 (30), p.9050-9059

2003

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A Structure-based Interpretation of E. coli GrpE Thermodynamic Properties

Journal of molecular biology, 2002-10, Vol.323 (1), p.131-142

2002

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Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus

Nature communications, 2022-03, Vol.13 (1), p.1222-15, Article 1222

2022

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Publisher Correction: Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus

Nature communications, 2022-04, Vol.13 (1), p.1962-2, Article 1962

2022

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Crystal Structure of an Ephrin Ectodomain

Developmental cell, 2001-07, Vol.1 (1), p.83-92

2001

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Mutational Analysis of the Energetics of the GrpE·DnaK Binding Interface: Equilibrium Association Constants by Sedimentation Velocity Analytical Ultracentrifugation

Journal of molecular biology, 2004-05, Vol.339 (2), p.447-458

2004

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Mutational analysis of the energetics of the GrpE.DnaK binding interface: equilibrium association constants by sedimentation velocity analytical ultracentrifugation

Journal of molecular biology, 2004-05, Vol.339 (2), p.447-458

2004

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A structure-based interpretation of E.coli GrpE thermodynamic properties

Journal of molecular biology, 2002-10, Vol.323 (1), p.131-142

2002

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Structural and functional studies of the telomere capping proteins Stn1, Ten1, and Cdc13

Gelinas, Amy D

2010

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Reduced GABAergic Neuron Excitability, Altered Synaptic Connectivity, and Seizures in a KCNT1 Gain-of-Function Mouse Model of Childhood Epilepsy

Cell reports (Cambridge), 2020-10, Vol.33 (4), p.108303-108303, Article 108303

2020

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Evidence for systemic immune system alterations in sporadic amyotrophic lateral sclerosis (sALS)

Journal of neuroimmunology, 2005-02, Vol.159 (1), p.215-224

2005

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MCP-1 chemokine receptor CCR2 is decreased on circulating monocytes in sporadic amyotrophic lateral sclerosis (sALS)

Journal of neuroimmunology, 2006-10, Vol.179 (1), p.87-93

2006

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Effects of codon optimization on coagulation factor IX translation and structure: Implications for protein and gene therapies

Scientific reports, 2019-10, Vol.9 (1), p.15449-15, Article 15449

2019

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Embracing proteins: structural themes in aptamer–protein complexes

Nucleic Acid Ligands With Protein-like Side Chains: Modified Aptamers and Their Use as Diagnostic and Therapeutic Agents

Structural basis for IL-1α recognition by a modified DNA aptamer that specifically inhibits IL-1α signaling

Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets

Broadly neutralizing aptamers to SARS-CoV-2: A diverse panel of modified DNA antiviral agents

Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor

Telomere capping proteins are structurally related to RPA with an additional telomere-specific domain

Evolving A RIG-I Antagonist: A Modified DNA Aptamer Mimics Viral RNA

Modified nucleotides may have enhanced early RNA catalysis

Crystal Structure of Interleukin-6 in Complex with a Modified Nucleic Acid Ligand

Modified aptamers as reagents to characterize recombinant human erythropoietin products

Sequence-Specific Binding to Telomeric DNA Is Not a Conserved Property of the Cdc13 DNA Binding Domain

Thermodynamic Linkage in the GrpE Nucleotide Exchange Factor, a Molecular Thermosensor

A Structure-based Interpretation of E. coli GrpE Thermodynamic Properties

Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus

Publisher Correction: Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus

Crystal Structure of an Ephrin Ectodomain

Mutational Analysis of the Energetics of the GrpE·DnaK Binding Interface: Equilibrium Association Constants by Sedimentation Velocity Analytical Ultracentrifugation

Mutational analysis of the energetics of the GrpE.DnaK binding interface: equilibrium association constants by sedimentation velocity analytical ultracentrifugation

A structure-based interpretation of E.coli GrpE thermodynamic properties

Structural and functional studies of the telomere capping proteins Stn1, Ten1, and Cdc13

Reduced GABAergic Neuron Excitability, Altered Synaptic Connectivity, and Seizures in a KCNT1 Gain-of-Function Mouse Model of Childhood Epilepsy

Evidence for systemic immune system alterations in sporadic amyotrophic lateral sclerosis (sALS)

MCP-1 chemokine receptor CCR2 is decreased on circulating monocytes in sporadic amyotrophic lateral sclerosis (sALS)

Effects of codon optimization on coagulation factor IX translation and structure: Implications for protein and gene therapies

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