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Specificity of substrate and inhibitor probes for human cytochromes P450 1A1 and 1A2

The Journal of pharmacology and experimental therapeutics, 1993-04, Vol.265 (1), p.401

1993

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Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions

Chemical research in toxicology, 1992-01, Vol.5 (1), p.54-59

1992

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Role of human hepatic cytochrome P450 1A2 and 3A4 in the metabolic activation of estrone

Carcinogenesis (New York), 1997, Vol.18 (1), p.207-214

1997

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Monoclonal Antibodies and Multifunctional Cytochrome P450: Drug Metabolism as Paradigm

Journal of clinical pharmacology, 2006-03, Vol.46 (3), p.353-372

2006

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Cytochromes P450 2A6, 2E1, and 3A and production of protein-aldehyde adducts in the liver of patients with alcoholic and non-alcoholic liver diseases

Journal of hepatology, 2000-12, Vol.33 (6), p.893-901

2000

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Targeted disruption of the microsomal epoxide hydrolase gene. Microsomal epoxide hydrolase is required for the carcinogenic activity of 7,12-dimethylbenz[a]anthracene

The Journal of biological chemistry, 1999-08, Vol.274 (34), p.23963-23968

1999

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Role of Human Cytochromes P450 in the Metabolic Activation of Chemical Carcinogens and Toxins

Drug metabolism reviews, 1994, Vol.26 (1-2), p.165-183

1994

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Further characterization of the expression in liver and catalytic activity of CYP2B6

The Journal of pharmacology and experimental therapeutics, 1998-09, Vol.286 (3), p.1253

1998

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Identification of cytochromes P 450 2C9 and 3A4 as the major catalysts of phenprocoumon hydroxylation in vitro

European journal of clinical pharmacology, 2004-05, Vol.60 (3), p.173-182

2004

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Identification of cytochromes P450 2C9 and 3A4 as the major catalysts of phenprocoumon hydroxylation in vitro

European journal of clinical pharmacology, 2004-05, Vol.60 (3), p.173-182

2004

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Enhancement of Cardiac L-Type Ca2+ Currents in Transgenic Mice with Cardiac-Specific Overexpression of CYP2J2

Molecular pharmacology, 2004-12, Vol.66 (6), p.1607-1616

2004

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Assessment of specificity of eight chemical inhibitors using cDNA-expressed cytochromes P450

Xenobiotica, 2000, Vol.30 (4), p.327-343

2000

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A comparison of relative abundance, activity factor and inhibitory monoclonal antibody approaches in the characterization of human CYP enzymology

British journal of clinical pharmacology, 2003-02, Vol.55 (2), p.175-181

2003

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4-Hydroxylation of debrisoquine by human CYP1A1 and its inhibition by quinidine and quinine

The Journal of pharmacology and experimental therapeutics, 2002-06, Vol.301 (3), p.1025-1032

2002

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Stereoselective Epoxidation and Hydration at the K-Region of Polycyclic Aromatic Hydrocarbons by cDNA-expressed Cytochromes P450 1A1, 1A2, and Epoxide Hydrolase

Biochemistry (Easton), 1996-12, Vol.35 (49), p.15807-15813

1996

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Cytochrome P450 and monoclonal antibodies

Pharmacological reviews, 1993-12, Vol.45 (4), p.413

Gelboin, H V

1993

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CYP2C subfamily, primarily CYP2C9, catalyses the enantioselective demethylation of the endocrine disruptor pesticide methoxychlor in human liver microsomes: use of inhibitory monoclonal antibodies in P450 identification

Xenobiotica, 2004-02, Vol.34 (2), p.117-132

2004

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A tobacco smoke-derived nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, is activated by multiple human cytochrome P450s including the polymorphic human cytochrome P4502D6

Carcinogenesis (New York), 1991-07, Vol.12 (7), p.1197-1201

1991

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The role of 12 cDNA-expressed human, rodent, and rabbit cytochromes P450 in the metabolism of benzo[a]pyrene and benzo[a]pyrene trans-7, 8-dihydrodiol

Molecular carcinogenesis, 1994-07, Vol.10 (3), p.159-168

1994

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Characterization of the common genetic defect in humans deficient in debrisoquine metabolism

Nature (London), 1988-02, Vol.331 (6155), p.442-446

1988

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Metabolic activation of the potent carcinogen dibenzo[a, l]pyrene by human recombinant cytochromes P450, lung and liver microsomes

Carcinogenesis (New York), 1996-11, Vol.17 (11), p.2429-2433

1996

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Use of inhibitory monoclonal antibodies to assess the contribution of cytochromes P450 to human drug metabolism

European journal of pharmacology, 2000-04, Vol.394 (2), p.199-209

2000

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Styrene Metabolism by cDNA-Expressed Human Hepatic and Pulmonary Cytochromes P450

Chemical research in toxicology, 1994-11, Vol.7 (6), p.891-896

1994

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Monoclonal antibodies specific and inhibitory to human cytochromes P450 2C8, 2C9, and 2C19

Drug metabolism and disposition, 2001-11, Vol.29 (11), p.1410

2001

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Induction of Rat Hepatic N-Nitrosodimethylamine Demethylase by Acetone Is Due to Protein Stabilization

The Journal of biological chemistry, 1989-02, Vol.264 (6), p.3568-3572

1989

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Specificity of substrate and inhibitor probes for human cytochromes P450 1A1 and 1A2

Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions

Role of human hepatic cytochrome P450 1A2 and 3A4 in the metabolic activation of estrone

Monoclonal Antibodies and Multifunctional Cytochrome P450: Drug Metabolism as Paradigm

Cytochromes P450 2A6, 2E1, and 3A and production of protein-aldehyde adducts in the liver of patients with alcoholic and non-alcoholic liver diseases

Targeted disruption of the microsomal epoxide hydrolase gene. Microsomal epoxide hydrolase is required for the carcinogenic activity of 7,12-dimethylbenz[a]anthracene

Role of Human Cytochromes P450 in the Metabolic Activation of Chemical Carcinogens and Toxins

Further characterization of the expression in liver and catalytic activity of CYP2B6

Identification of cytochromes P 450 2C9 and 3A4 as the major catalysts of phenprocoumon hydroxylation in vitro

Identification of cytochromes P450 2C9 and 3A4 as the major catalysts of phenprocoumon hydroxylation in vitro

Enhancement of Cardiac L-Type Ca2+ Currents in Transgenic Mice with Cardiac-Specific Overexpression of CYP2J2

Assessment of specificity of eight chemical inhibitors using cDNA-expressed cytochromes P450

A comparison of relative abundance, activity factor and inhibitory monoclonal antibody approaches in the characterization of human CYP enzymology

4-Hydroxylation of debrisoquine by human CYP1A1 and its inhibition by quinidine and quinine

Stereoselective Epoxidation and Hydration at the K-Region of Polycyclic Aromatic Hydrocarbons by cDNA-expressed Cytochromes P450 1A1, 1A2, and Epoxide Hydrolase

Cytochrome P450 and monoclonal antibodies

CYP2C subfamily, primarily CYP2C9, catalyses the enantioselective demethylation of the endocrine disruptor pesticide methoxychlor in human liver microsomes: use of inhibitory monoclonal antibodies in P450 identification

A tobacco smoke-derived nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, is activated by multiple human cytochrome P450s including the polymorphic human cytochrome P4502D6

The role of 12 cDNA-expressed human, rodent, and rabbit cytochromes P450 in the metabolism of benzo[a]pyrene and benzo[a]pyrene trans-7, 8-dihydrodiol

Characterization of the common genetic defect in humans deficient in debrisoquine metabolism

Metabolic activation of the potent carcinogen dibenzo[a, l]pyrene by human recombinant cytochromes P450, lung and liver microsomes

Use of inhibitory monoclonal antibodies to assess the contribution of cytochromes P450 to human drug metabolism

Styrene Metabolism by cDNA-Expressed Human Hepatic and Pulmonary Cytochromes P450

Monoclonal antibodies specific and inhibitory to human cytochromes P450 2C8, 2C9, and 2C19

Induction of Rat Hepatic N-Nitrosodimethylamine Demethylase by Acetone Is Due to Protein Stabilization

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