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Measuring nanoscale viscoelastic parameters of cells directly from AFM force-displacement curves

Scientific reports, 2017-05, Vol.7 (1), p.1541-14, Article 1541

2017

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Calling in SYK: SYK's dual role as a tumor promoter and tumor suppressor in cancer

Biochimica et biophysica acta, 2015-01, Vol.1853 (1), p.254-263

2015

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Fast, multi-frequency, and quantitative nanomechanical mapping of live cells using the atomic force microscope

Scientific reports, 2015-06, Vol.5 (1), p.11692-11692, Article 11692

2015

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Getting Syk: spleen tyrosine kinase as a therapeutic target

Trends in pharmacological sciences (Regular ed.), 2014-08, Vol.35 (8), p.414-422

Geahlen, Robert L

2014

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Sensitive kinase assay linked with phosphoproteomics for identifying direct kinase substrates

Proceedings of the National Academy of Sciences - PNAS, 2012-04, Vol.109 (15), p.5615-5620

2012

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Identification of Direct Tyrosine Kinase Substrates Based on Protein Kinase Assay-Linked Phosphoproteomics

Molecular & cellular proteomics, 2013-10, Vol.12 (10), p.2969-2980

2013

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Stress Granules Modulate SYK to Cause Microglial Cell Dysfunction in Alzheimer's Disease

EBioMedicine, 2015-11, Vol.2 (11), p.1785-1798

2015

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Syk and pTyr'd: Signaling through the B cell antigen receptor

Biochimica et biophysica acta, 2009-07, Vol.1793 (7), p.1115-1127

Geahlen, Robert L.

2009

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Role of the Protein Tyrosine Kinase Syk in Regulating Cell-Cell Adhesion and Motility in Breast Cancer Cells

Molecular cancer research, 2009-05, Vol.7 (5), p.634-644

2009

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One-step extraction of subcellular proteins from eukaryotic cells

Lab on a chip, 2010-08, Vol.10 (16), p.2046-2048

2010

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Spleen Tyrosine Kinase-Mediated Autophagy Is Required for Epithelial-Mesenchymal Plasticity and Metastasis in Breast Cancer

Cancer research (Chicago, Ill.), 2019-04, Vol.79 (8), p.1831-1843

2019

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Regulation of epithelial-mesenchymal transition and metastasis by TGF-β, P-bodies, and autophagy

Oncotarget, 2017-11, Vol.8 (61), p.103302-103314

2017

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Quantitative analysis of protein translocations by microfluidic total internal reflection fluorescence flow cytometry

Lab on a chip, 2010-10, Vol.1 (2), p.2673-2679

2010

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Nanomechanical Property Maps of Breast Cancer Cells As Determined by Multiharmonic Atomic Force Microscopy Reveal Syk-Dependent Changes in Microtubule Stability Mediated by MAP1B

Biochemistry (Easton), 2015-01, Vol.54 (1), p.60-68

2015

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Modulation of BCR Signaling by the Induced Dimerization of Receptor-Associated SYK

Antibodies (Basel), 2017-12, Vol.6 (4), p.23

2017

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Two Closely Spaced Tyrosines Regulate NFAT Signaling in B Cells via Syk Association with Vav

Molecular and Cellular Biology, 2011-07, Vol.31 (14), p.2984-2996

2011

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Molecular Basis for a Direct Interaction between the Syk Protein-tyrosine Kinase and Phosphoinositide 3-Kinase

The Journal of biological chemistry, 2005-01, Vol.280 (2), p.1543-1551

2005

Volltextzugriff (PDF)

Nucleocytoplasmic Trafficking of the Syk Protein Tyrosine Kinase

Molecular and Cellular Biology, 2006-05, Vol.26 (9), p.3478-3491

2006

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Tyr130 phosphorylation triggers Syk release from antigen receptor by long-distance conformational uncoupling

Proceedings of the National Academy of Sciences - PNAS, 2008-08, Vol.105 (33), p.11760-11765

2008

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Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk

Nature (London), 1995-11, Vol.378 (6554), p.298-302

1995

Volltextzugriff (PDF)

In-depth Analyses of Kinase-dependent Tyrosine Phosphoproteomes Based on Metal Ion-functionalized Soluble Nanopolymers

Molecular & cellular proteomics, 2010-10, Vol.9 (10), p.2162-2172

2010

Volltextzugriff (PDF)

Syk interacts with and phosphorylates nucleolin to stabilize Bcl-x(L) mRNA and promote cell survival

Molecular and cellular biology, 2014-10, Vol.34 (20), p.3788

2014

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Syk Is Recruited to Stress Granules and Promotes Their Clearance through Autophagy

The Journal of biological chemistry, 2015-11, Vol.290 (46), p.27803-27815

2015

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Identification of Upstream Kinases by Fluorescence Complementation Mass Spectrometry

ACS central science, 2017-10, Vol.3 (10), p.1078-1085

2017

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The microtubule-associated protein tau is phosphorylated by Syk

Biochimica et biophysica acta, 2008-02, Vol.1783 (2), p.188-192

2008

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Measuring nanoscale viscoelastic parameters of cells directly from AFM force-displacement curves

Calling in SYK: SYK's dual role as a tumor promoter and tumor suppressor in cancer

Fast, multi-frequency, and quantitative nanomechanical mapping of live cells using the atomic force microscope

Getting Syk: spleen tyrosine kinase as a therapeutic target

Sensitive kinase assay linked with phosphoproteomics for identifying direct kinase substrates

Identification of Direct Tyrosine Kinase Substrates Based on Protein Kinase Assay-Linked Phosphoproteomics

Stress Granules Modulate SYK to Cause Microglial Cell Dysfunction in Alzheimer's Disease

Syk and pTyr'd: Signaling through the B cell antigen receptor

Role of the Protein Tyrosine Kinase Syk in Regulating Cell-Cell Adhesion and Motility in Breast Cancer Cells

One-step extraction of subcellular proteins from eukaryotic cells

Spleen Tyrosine Kinase-Mediated Autophagy Is Required for Epithelial-Mesenchymal Plasticity and Metastasis in Breast Cancer

Regulation of epithelial-mesenchymal transition and metastasis by TGF-β, P-bodies, and autophagy

Quantitative analysis of protein translocations by microfluidic total internal reflection fluorescence flow cytometry

Nanomechanical Property Maps of Breast Cancer Cells As Determined by Multiharmonic Atomic Force Microscopy Reveal Syk-Dependent Changes in Microtubule Stability Mediated by MAP1B

Modulation of BCR Signaling by the Induced Dimerization of Receptor-Associated SYK

Two Closely Spaced Tyrosines Regulate NFAT Signaling in B Cells via Syk Association with Vav

Molecular Basis for a Direct Interaction between the Syk Protein-tyrosine Kinase and Phosphoinositide 3-Kinase

Nucleocytoplasmic Trafficking of the Syk Protein Tyrosine Kinase

Tyr130 phosphorylation triggers Syk release from antigen receptor by long-distance conformational uncoupling

Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk

In-depth Analyses of Kinase-dependent Tyrosine Phosphoproteomes Based on Metal Ion-functionalized Soluble Nanopolymers

Syk interacts with and phosphorylates nucleolin to stabilize Bcl-x(L) mRNA and promote cell survival

Syk Is Recruited to Stress Granules and Promotes Their Clearance through Autophagy

Identification of Upstream Kinases by Fluorescence Complementation Mass Spectrometry

The microtubule-associated protein tau is phosphorylated by Syk

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