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Assembly and localization of Toll-like receptor signalling complexes

Nature reviews. Immunology, 2014-08, Vol.14 (8), p.546-558

2014

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Structure and function of Toll receptors and their ligands

Annual review of biochemistry, 2007-01, Vol.76 (1), p.141-165

2007

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Role of self-organising myddosome oligomers in inflammatory signalling by Toll-like receptors

BMC biology, 2019-02, Vol.17 (1), p.15-15, Article 15

Gay, Nicholas J

2019

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The molecular basis of the host response to lipopolysaccharide

Nature reviews. Microbiology, 2010-01, Vol.8 (1), p.8-14

2010

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MyD88 Death-Domain Oligomerization Determines Myddosome Architecture: Implications for Toll-like Receptor Signaling

Structure (London), 2020-03, Vol.28 (3), p.281-289.e3

2020

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Adaptors in toll-like receptor signaling and their potential as therapeutic targets

Current drug targets, 2012-10, Vol.13 (11), p.1360-1374

2012

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Molecular and cellular regulation of toll-like receptor-4 activity induced by lipopolysaccharide ligands

Frontiers in immunology, 2014-10, Vol.5, p.473-473

2014

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What the Myddosome structure tells us about the initiation of innate immunity

Trends in immunology, 2011-03, Vol.32 (3), p.104-109

2011

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The lectin-specific activity of Toxoplasma gondii microneme proteins 1 and 4 binds Toll-like receptor 2 and 4 N-glycans to regulate innate immune priming

PLoS pathogens, 2019-06, Vol.15 (6), p.e1007871-e1007871

2019

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Activation of Toll-like receptor 4 by Ebola virus-shed glycoprotein is direct and requires the internal fusion loop but not glycosylation

Cell reports (Cambridge), 2022-10, Vol.41 (4), p.111562-111562, Article 111562

2022

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Toll-like receptor signalling through macromolecular protein complexes

Molecular immunology, 2015-02, Vol.63 (2), p.162-165

2015

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An Oligomeric Signaling Platform Formed by the Toll-like Receptor Signal Transducers MyD88 and IRAK-4

The Journal of biological chemistry, 2009-09, Vol.284 (37), p.25404-25411

2009

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Activation of Toll-like receptors nucleates assembly of the MyDDosome signaling hub

eLife, 2018-01, Vol.7

2018

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Targeting and Recognition of Toll-Like Receptors by Plant and Pathogen Lectins

Frontiers in immunology, 2017-12, Vol.8, p.1820-1820

2017

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The COP II adaptor protein TMED7 is required to initiate and mediate the delivery of TLR4 to the plasma membrane

Science signaling, 2014-07, Vol.7 (336), p.ra70

2014

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A quantitative comparison of single-dye tracking analysis tools using Monte Carlo simulations

PloS one, 2013-05, Vol.8 (5), p.e64287-e64287

2013

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Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection

Proceedings of the National Academy of Sciences - PNAS, 2011-09, Vol.108 (36), p.14879-14884

2011

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Toll-6 and Toll-7 function as neurotrophin receptors in the Drosophila melanogaster CNS

Nature neuroscience, 2013-09, Vol.16 (9), p.1248-1256

2013

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Saturation of acyl chains converts cardiolipin from an antagonist to an activator of Toll-like receptor-4

Cellular and molecular life sciences : CMLS, 2019-09, Vol.76 (18), p.3667-3678

2019

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Three-tier regulation of cell number plasticity by neurotrophins and Tolls in Drosophila

The Journal of cell biology, 2017-05, Vol.216 (5), p.1421-1438

2017

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Structure of the Toll/Interleukin-1 Receptor (TIR) Domain of the B-cell Adaptor That Links Phosphoinositide Metabolism with the Negative Regulation of the Toll-like Receptor (TLR) Signalosome

The Journal of biological chemistry, 2017-01, Vol.292 (2), p.652-660

2017

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Structure and dynamics of Toll immunoreceptor activation in the mosquito Aedes aegypti

Nature communications, 2022-08, Vol.13 (1), p.5110-5110, Article 5110

2022

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A dimer of the Toll-like receptor 4 cytoplasmic domain provides a specific scaffold for the recruitment of signalling adaptor proteins

PloS one, 2007-08, Vol.2 (8), p.e788

2007

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Anterograde trafficking of Toll-like receptors requires the cargo sorting adaptors TMED-2 and 7

Traffic (Copenhagen, Denmark), 2023-11, Vol.24 (11), p.508-521

2023

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Kek-6: A truncated-Trk-like receptor for Drosophila neurotrophin 2 regulates structural synaptic plasticity

PLoS genetics, 2017-08, Vol.13 (8), p.e1006968-e1006968

2017

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Assembly and localization of Toll-like receptor signalling complexes

Structure and function of Toll receptors and their ligands

Role of self-organising myddosome oligomers in inflammatory signalling by Toll-like receptors

The molecular basis of the host response to lipopolysaccharide

MyD88 Death-Domain Oligomerization Determines Myddosome Architecture: Implications for Toll-like Receptor Signaling

Adaptors in toll-like receptor signaling and their potential as therapeutic targets

Molecular and cellular regulation of toll-like receptor-4 activity induced by lipopolysaccharide ligands

What the Myddosome structure tells us about the initiation of innate immunity

The lectin-specific activity of Toxoplasma gondii microneme proteins 1 and 4 binds Toll-like receptor 2 and 4 N-glycans to regulate innate immune priming

Activation of Toll-like receptor 4 by Ebola virus-shed glycoprotein is direct and requires the internal fusion loop but not glycosylation

Toll-like receptor signalling through macromolecular protein complexes

An Oligomeric Signaling Platform Formed by the Toll-like Receptor Signal Transducers MyD88 and IRAK-4

Activation of Toll-like receptors nucleates assembly of the MyDDosome signaling hub

Targeting and Recognition of Toll-Like Receptors by Plant and Pathogen Lectins

The COP II adaptor protein TMED7 is required to initiate and mediate the delivery of TLR4 to the plasma membrane

A quantitative comparison of single-dye tracking analysis tools using Monte Carlo simulations

Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection

Toll-6 and Toll-7 function as neurotrophin receptors in the Drosophila melanogaster CNS

Saturation of acyl chains converts cardiolipin from an antagonist to an activator of Toll-like receptor-4

Three-tier regulation of cell number plasticity by neurotrophins and Tolls in Drosophila

Structure of the Toll/Interleukin-1 Receptor (TIR) Domain of the B-cell Adaptor That Links Phosphoinositide Metabolism with the Negative Regulation of the Toll-like Receptor (TLR) Signalosome

Structure and dynamics of Toll immunoreceptor activation in the mosquito Aedes aegypti

A dimer of the Toll-like receptor 4 cytoplasmic domain provides a specific scaffold for the recruitment of signalling adaptor proteins

Anterograde trafficking of Toll-like receptors requires the cargo sorting adaptors TMED-2 and 7

Kek-6: A truncated-Trk-like receptor for Drosophila neurotrophin 2 regulates structural synaptic plasticity

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