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Editorial: Ion channels and transporters as drug targets in immune disorders

Frontiers in pharmacology, 2024-06, Vol.15, p.1439156

2024

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Immune and ionic mechanisms mediating the effect of dexamethasone in severe COVID-19

Frontiers in immunology, 2023-03, Vol.14, p.1143350-1143350

2023

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Exploring the therapeutic opportunities of potassium channels for the treatment of rheumatoid arthritis

Frontiers in pharmacology, 2024-05, Vol.15, p.1286069-1286069

2024

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Oral batyl alcohol supplementation rescues decreased cardiac conduction in ether phospholipid‐deficient mice

Journal of inherited metabolic disease, 2020-09, Vol.43 (5), p.1046-1055

2020

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How the Potassium Channel Response of T Lymphocytes to the Tumor Microenvironment Shapes Antitumor Immunity

Cancers, 2022-07, Vol.14 (15), p.3564

2022

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A Compartmentalized Reduction in Membrane-Proximal Calmodulin Reduces the Immune Surveillance Capabilities of CD8 + T Cells in Head and Neck Cancer

Frontiers in pharmacology, 2020-02, Vol.11, p.143

2020

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Immune Checkpoint Inhibitors Regulate K+ Channel Activity in Cytotoxic T Lymphocytes of Head and Neck Cancer Patients

Frontiers in pharmacology, 2021-08, Vol.12, p.742862-742862

2021

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Reuse of Molecules for Glioblastoma Therapy

Pharmaceuticals (Basel, Switzerland), 2021-01, Vol.14 (2), p.99

2021

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Proper Voltage-Dependent Ion Channel Function in Dysferlin-Deficient Cardiomyocytes

Cellular physiology and biochemistry, 2015-01, Vol.36 (3), p.1049-1058

2015

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Therapeutically leveraging GABAA receptors in cancer

Experimental biology and medicine (Maywood, N.J.), 2021-10, Vol.246 (19), p.2128-2135

2021

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Therapeutically leveraging GABA A receptors in cancer

Experimental biology and medicine (Maywood, N.J.), 2021-10, Vol.246 (19), p.2128-2135

2021

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Screening Ion Channels in Cancer Cells

Journal of visualized experiments, 2023-06 (196)

2023

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Mechanism of hERG channel block by the psychoactive indole alkaloid ibogaine

The Journal of pharmacology and experimental therapeutics, 2014-02, Vol.348 (2), p.346-358

2014

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Anti-addiction drug ibogaine inhibits voltage-gated ionic currents: A study to assess the drug's cardiac ion channel profile

Toxicology and applied pharmacology, 2013-12, Vol.273 (2), p.259-268

2013

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Mechanism of Modification, by Lidocaine, of Fast and Slow Recovery from Inactivation of Voltage-Gated Na⁺ Channels

Molecular pharmacology, 2015-11, Vol.88 (5), p.866-879

2015

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Distinct modulation of inactivation by a residue in the pore domain of voltage-gated Na + channels: mechanistic insights from recent crystal structures

Scientific reports, 2018-01, Vol.8 (1), p.631-15, Article 631

2018

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C2‐Modified Sparteine Derivatives Are a New Class of Potentially Long‐Acting Sodium Channel Blockers

ChemMedChem, 2017-11, Vol.12 (22), p.1819-1822

2017

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PD1 blockade enhances K + channel activity, Ca 2+ signaling, and migratory ability in cytotoxic T lymphocytes of patients with head and neck cancer

Journal for immunotherapy of cancer, 2020-10, Vol.8 (2), p.e000844

2020

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Exploring the Structure of the Voltage-gated Na+ Channel by an Engineered Drug Access Pathway to the Receptor Site for Local Anesthetics

The Journal of biological chemistry, 2014-08, Vol.289 (31), p.21770-21781

2014

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PD1 blockade enhances K+ channel activity, Ca2+ signaling, and migratory ability in cytotoxic T lymphocytes of patients with head and neck cancer

Journal for immunotherapy of cancer, 2020-10, Vol.8 (2)

2020

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Molecular mechanisms of dexamethasone-mediated modulation of inflammatory and interferon responses in severe COVID-19 patients

The Journal of immunology (1950), 2022-05, Vol.208 (1_Supplement), p.161-161.11

2022

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Pembrolizumab treatment increases chemotaxis of cytotoxic T cells in head and neck cancer patients within the adenosine‐rich tumor microenvironment

The FASEB journal, 2020-04, Vol.34 (S1), p.1-1

2020

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Failure to upregulate calmodulin underlies the suppressed KCa3.1 function and enhanced sensitivity to adenosine in CD8+ T cells of head and neck cancer patients

The Journal of immunology (1950), 2018-05, Vol.200 (1_Supplement), p.57-57.8

2018

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Pembrolizumab treatment increases K+ channel function and calcium fluxes in cytotoxic T cells of head and neck cancer patients

The Journal of immunology (1950), 2020-05, Vol.204 (1_Supplement), p.165-165.41

2020

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Editorial: Ion channels and transporters as drug targets in immune disorders

Immune and ionic mechanisms mediating the effect of dexamethasone in severe COVID-19

Exploring the therapeutic opportunities of potassium channels for the treatment of rheumatoid arthritis

Oral batyl alcohol supplementation rescues decreased cardiac conduction in ether phospholipid‐deficient mice

How the Potassium Channel Response of T Lymphocytes to the Tumor Microenvironment Shapes Antitumor Immunity

A Compartmentalized Reduction in Membrane-Proximal Calmodulin Reduces the Immune Surveillance Capabilities of CD8 + T Cells in Head and Neck Cancer

Immune Checkpoint Inhibitors Regulate K+ Channel Activity in Cytotoxic T Lymphocytes of Head and Neck Cancer Patients

Reuse of Molecules for Glioblastoma Therapy

Proper Voltage-Dependent Ion Channel Function in Dysferlin-Deficient Cardiomyocytes

Therapeutically leveraging GABAA receptors in cancer

Therapeutically leveraging GABA A receptors in cancer

Screening Ion Channels in Cancer Cells

Mechanism of hERG channel block by the psychoactive indole alkaloid ibogaine

Anti-addiction drug ibogaine inhibits voltage-gated ionic currents: A study to assess the drug's cardiac ion channel profile

Mechanism of Modification, by Lidocaine, of Fast and Slow Recovery from Inactivation of Voltage-Gated Na⁺ Channels

Distinct modulation of inactivation by a residue in the pore domain of voltage-gated Na + channels: mechanistic insights from recent crystal structures

C2‐Modified Sparteine Derivatives Are a New Class of Potentially Long‐Acting Sodium Channel Blockers

PD1 blockade enhances K + channel activity, Ca 2+ signaling, and migratory ability in cytotoxic T lymphocytes of patients with head and neck cancer

Exploring the Structure of the Voltage-gated Na+ Channel by an Engineered Drug Access Pathway to the Receptor Site for Local Anesthetics

PD1 blockade enhances K+ channel activity, Ca2+ signaling, and migratory ability in cytotoxic T lymphocytes of patients with head and neck cancer

Molecular mechanisms of dexamethasone-mediated modulation of inflammatory and interferon responses in severe COVID-19 patients

Pembrolizumab treatment increases chemotaxis of cytotoxic T cells in head and neck cancer patients within the adenosine‐rich tumor microenvironment

Failure to upregulate calmodulin underlies the suppressed KCa3.1 function and enhanced sensitivity to adenosine in CD8+ T cells of head and neck cancer patients

Pembrolizumab treatment increases K+ channel function and calcium fluxes in cytotoxic T cells of head and neck cancer patients

GABA(A) Receptor Activation Drives GABARAP–Nix Mediated Autophagy to Radiation-Sensitize Primary and Brain-Metastatic Lung Adenocarcinoma Tumors

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