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Cleavage of DNA and RNA by PLD3 and PLD4 limits autoinflammatory triggering by multiple sensors

Nature communications, 2021-10, Vol.12 (1), p.5874-5874, Article 5874

2021

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Adjuvant-Enhanced Antibody Responses in the Absence of Toll-Like Receptor Signaling

Science (American Association for the Advancement of Science), 2006-12, Vol.314 (5807), p.1936-1938

2006

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The Bacterial Peptidoglycan-Sensing Molecules NOD1 and NOD2 Promote CD8 + Thymocyte Selection

The Journal of immunology (1950), 2017-04, Vol.198 (7), p.2649-2660

2017

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Dissecting the Ability of Siglecs To Antagonize Fcγ Receptors

ACS central science, 2024-02, Vol.10 (2), p.315-330

2024

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Metabolic reprogramming is required for antibody production that is suppressed in anergic but exaggerated in chronically BAFF-exposed B cells

The Journal of immunology (1950), 2014-04, Vol.192 (8), p.3626-3636

2014

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FGD2, a CDC42-specific Exchange Factor Expressed by Antigen-presenting Cells, Localizes to Early Endosomes and Active Membrane Ruffles

The Journal of biological chemistry, 2008-12, Vol.283 (49), p.34002-34012

2008

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PLD3 and PLD4 are single-stranded acid exonucleases that regulate endosomal nucleic-acid sensing

Nature immunology, 2018-09, Vol.19 (9), p.942-953

2018

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Depth Moderates DOC Impact on Cold‐Water Refugia in Small, Northern Temperate Lakes

Water resources research, 2023-06, Vol.59 (6), p.n/a

2023

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Regulation of the B cell receptor repertoire and self-reactivity by BAFF

The Journal of immunology (1950), 2010-10, Vol.185 (7), p.4128-4136

2010

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Activated protein C ameliorates chronic graft-versus-host disease by PAR1-dependent biased cell signaling on T cells

Blood, 2019-08, Vol.134 (9), p.776-781

2019

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Lack of Both Nucleotide-Binding Oligomerization Domain-Containing Proteins 1 and 2 Primes T Cells for Activation-Induced Cell Death

The Journal of immunology (1950), 2017-08, Vol.199 (3), p.1196-1205

2017

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Disease in the Pld4thss/thss Model of Murine Lupus Requires TLR9

ImmunoHorizons, 2023-08, Vol.7 (8), p.577-586

2023

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Liver-expressed Igκ superantigen induces tolerance of polyclonal B cells by clonal deletion not κ to λ receptor editing

The Journal of experimental medicine, 2011-03, Vol.208 (3), p.617-629

2011

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B lymphocyte stimulator (BLyS) isoforms in systemic lupus erythematosus: disease activity correlates better with blood leukocyte BLyS mRNA levels than with plasma BLyS protein levels

Arthritis research & therapy, 2006-01, Vol.8 (1), p.R6-R6

2006

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Repertoire-based selection into the marginal zone compartment during B cell development

The Journal of experimental medicine, 2008-09, Vol.205 (9), p.2043-2052

2008

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Protein kinase C η is required for T cell activation and homeostatic proliferation

Science signaling, 2011-12, Vol.4 (202), p.ra84

2011

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ΔBAFF, an Alternate Splice Isoform That Regulates Receptor Binding and Biopresentation of the B Cell Survival Cytokine, BAFF

The Journal of biological chemistry, 2003-10, Vol.278 (40), p.38220-38228

2003

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ΔBAFF, a Splice Isoform of BAFF, Opposes Full-Length BAFF Activity In Vivo in Transgenic Mouse Models

The Journal of immunology (1950), 2005-07, Vol.175 (1), p.319-328

2005

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FcγRI-Deficient Mice Show Multiple Alterations to Inflammatory and Immune Responses

Immunity (Cambridge, Mass.), 2002-03, Vol.16 (3), p.379-389

2002

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Peripheral B Cell Tolerance and Function in Transgenic Mice Expressing an IgD Superantigen

The Journal of immunology (1950), 2010-04, Vol.184 (8), p.4143-4158

2010

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Deletion of IgG-switched autoreactive B cells and defects in Fas(lpr) lupus mice

The Journal of immunology (1950), 2010-07, Vol.185 (2), p.1015-1027

2010

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PLD3 and PLD4 are single-stranded acid exonucleases that regulate endosomal nucleicacid sensing

The Journal of immunology (1950), 2019-05, Vol.202 (1_Supplement), p.178-178.6

2019

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The ssDNA exonucleases PLD3 and PLD4 are required to prevent lethal primary HLH-like disease in mice

The Journal of immunology (1950), 2019-05, Vol.202 (1_Supplement), p.187-187.6

2019

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Expression level of a pancreatic neo-antigen in beta cells determines degree of diabetes pathogenesis

Journal of autoimmunity, 2010-12, Vol.35 (4), p.404-413

2010

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Effect of cell:cell competition and BAFF expression on peripheral B cell tolerance and B‐1 cell survival in transgenic mice expressing a low level of Igκ‐reactive macroself antigen

European journal of immunology, 2006-04, Vol.36 (4), p.985-996

2006

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Cleavage of DNA and RNA by PLD3 and PLD4 limits autoinflammatory triggering by multiple sensors

Adjuvant-Enhanced Antibody Responses in the Absence of Toll-Like Receptor Signaling

The Bacterial Peptidoglycan-Sensing Molecules NOD1 and NOD2 Promote CD8 + Thymocyte Selection

Dissecting the Ability of Siglecs To Antagonize Fcγ Receptors

Metabolic reprogramming is required for antibody production that is suppressed in anergic but exaggerated in chronically BAFF-exposed B cells

FGD2, a CDC42-specific Exchange Factor Expressed by Antigen-presenting Cells, Localizes to Early Endosomes and Active Membrane Ruffles

PLD3 and PLD4 are single-stranded acid exonucleases that regulate endosomal nucleic-acid sensing

Depth Moderates DOC Impact on Cold‐Water Refugia in Small, Northern Temperate Lakes

Regulation of the B cell receptor repertoire and self-reactivity by BAFF

Activated protein C ameliorates chronic graft-versus-host disease by PAR1-dependent biased cell signaling on T cells

Lack of Both Nucleotide-Binding Oligomerization Domain-Containing Proteins 1 and 2 Primes T Cells for Activation-Induced Cell Death

Disease in the Pld4thss/thss Model of Murine Lupus Requires TLR9

Liver-expressed Igκ superantigen induces tolerance of polyclonal B cells by clonal deletion not κ to λ receptor editing

B lymphocyte stimulator (BLyS) isoforms in systemic lupus erythematosus: disease activity correlates better with blood leukocyte BLyS mRNA levels than with plasma BLyS protein levels

Repertoire-based selection into the marginal zone compartment during B cell development

Protein kinase C η is required for T cell activation and homeostatic proliferation

ΔBAFF, an Alternate Splice Isoform That Regulates Receptor Binding and Biopresentation of the B Cell Survival Cytokine, BAFF

ΔBAFF, a Splice Isoform of BAFF, Opposes Full-Length BAFF Activity In Vivo in Transgenic Mouse Models

FcγRI-Deficient Mice Show Multiple Alterations to Inflammatory and Immune Responses

Peripheral B Cell Tolerance and Function in Transgenic Mice Expressing an IgD Superantigen

Deletion of IgG-switched autoreactive B cells and defects in Fas(lpr) lupus mice

PLD3 and PLD4 are single-stranded acid exonucleases that regulate endosomal nucleicacid sensing

The ssDNA exonucleases PLD3 and PLD4 are required to prevent lethal primary HLH-like disease in mice

Expression level of a pancreatic neo-antigen in beta cells determines degree of diabetes pathogenesis

Effect of cell:cell competition and BAFF expression on peripheral B cell tolerance and B‐1 cell survival in transgenic mice expressing a low level of Igκ‐reactive macroself antigen

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