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Activation of RNase L is dependent on OAS3 expression during infection with diverse human viruses

Proceedings of the National Academy of Sciences - PNAS, 2016-02, Vol.113 (8), p.2241-2246

2016

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OAS-RNase L innate immune pathway mediates the cytotoxicity of a DNA-demethylating drug

Proceedings of the National Academy of Sciences - PNAS, 2019-03, Vol.116 (11), p.5071-5076

2019

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Ribonuclease L mediates the cell-lethal phenotype of double-stranded RNA editing enzyme ADAR1 deficiency in a human cell line

eLife, 2017-03, Vol.6

2017

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Specificity and Mechanism of Coronavirus, Rotavirus, and Mammalian Two-Histidine Phosphoesterases That Antagonize Antiviral Innate Immunity

mBio, 2021-08, Vol.12 (4), p.e0178121-e0178121

2021

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Initiation of a ZAKα-dependent ribotoxic stress response by the innate immunity endoribonuclease RNase L

Cell reports (Cambridge), 2024-04, Vol.43 (4), p.113998-113998, Article 113998

2024

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RNase L Triggers Autophagy in Response to Viral Infections

Journal of Virology, 2012-10, Vol.86 (20), p.11311-11321

2012

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Dimeric Structure of Pseudokinase RNase L Bound to 2-5A Reveals a Basis for Interferon-Induced Antiviral Activity

Molecular cell, 2014-01, Vol.53 (2), p.221-234

2014

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The Effect of Primary Graft Dysfunction on Survival after Lung Transplantation

American journal of respiratory and critical care medicine, 2005-06, Vol.171 (11), p.1312-1316

2005

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Analogs of the Catechol Derivative Dynasore Inhibit HIV-1 Ribonuclease H, SARS-CoV-2 nsp14 Exoribonuclease, and Virus Replication

Viruses, 2023-07, Vol.15 (7), p.1539

2023

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Race and electronically measured adherence to immunosuppressive medications after deceased donor renal transplantation

Journal of the American Society of Nephrology, 2005-06, Vol.16 (6), p.1839-1848

2005

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Impact of Primary Graft Failure on Outcomes Following Lung Transplantation

Chest, 2005-01, Vol.127 (1), p.161-165

2005

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Integration Site Preference of Xenotropic Murine Leukemia Virus-Related Virus, a New Human Retrovirus Associated with Prostate Cancer

Journal of Virology, 2008-10, Vol.82 (20), p.9964-9977

2008

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Murine AKAP7 has a 2',5'-phosphodiesterase domain that can complement an inactive murine coronavirus ns2 gene

mBio, 2014-07, Vol.5 (4), p.e01312-e01314

2014

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In-depth investigation of archival and prospectively collected samples reveals no evidence for XMRV infection in prostate cancer

PloS one, 2012-09, Vol.7 (9), p.e44954-e44954

2012

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Fibrils of Prostatic Acid Phosphatase Fragments Boost Infections with XMRV (Xenotropic Murine Leukemia Virus-Related Virus), a Human Retrovirus Associated with Prostate Cancer

Journal of Virology, 2009-07, Vol.83 (14), p.6995-7003

2009

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Infection, Viral Dissemination, and Antibody Responses of Rhesus Macaques Exposed to the Human Gammaretrovirus XMRV

Journal of Virology, 2011-05, Vol.85 (9), p.4547-4557

2011

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Absence of XMRV and closely related viruses in primary prostate cancer tissues used to derive the XMRV-infected cell line 22Rv1

PloS one, 2012-05, Vol.7 (5), p.e36072-e36072

2012

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Identification of Small Molecule Inhibitors of RNase L by Fragment-Based Drug Discovery

Journal of medicinal chemistry, 2022-01, Vol.65 (2), p.1445-1457

2022

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Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication

PLoS pathogens, 2017-02, Vol.13 (2), p.e1006195-e1006195

2017

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Suppressing PAR ylation by 2′,5′‐oligoadenylate synthetase 1 inhibits DNA damage‐induced cell death

The EMBO journal, 2020-10, Vol.39 (20)

2020

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Suppressing PARylation by 2′,5′‐oligoadenylate synthetase 1 inhibits DNA damage‐induced cell death

The EMBO journal, 2020-06, Vol.39 (11), p.e101573-n/a

2020

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Suppressing PAR ylation by 2′,5′‐oligoadenylate synthetase 1 inhibits DNA damage‐induced cell death

The EMBO journal, 2020-06, Vol.39 (11)

2020

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A phenolic small molecule inhibitor of RNase L prevents cell death from ADAR1 deficiency

Proceedings of the National Academy of Sciences - PNAS, 2020-10, Vol.117 (40), p.24802-24812

2020

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Relationship of Estimated GFR and Coronary Artery Calcification in the CRIC (Chronic Renal Insufficiency Cohort) Study

American journal of kidney diseases, 2011-10, Vol.58 (4), p.519-526

2011

Volltextzugriff (PDF)

Suppressing PARylation by 2′,5′‐oligoadenylate synthetase 1 inhibits DNA damage‐induced cell death

The EMBO journal, 2020-10, Vol.39 (20), p.e106593-n/a

2020

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Activation of RNase L is dependent on OAS3 expression during infection with diverse human viruses

OAS-RNase L innate immune pathway mediates the cytotoxicity of a DNA-demethylating drug

Ribonuclease L mediates the cell-lethal phenotype of double-stranded RNA editing enzyme ADAR1 deficiency in a human cell line

Specificity and Mechanism of Coronavirus, Rotavirus, and Mammalian Two-Histidine Phosphoesterases That Antagonize Antiviral Innate Immunity

Initiation of a ZAKα-dependent ribotoxic stress response by the innate immunity endoribonuclease RNase L

RNase L Triggers Autophagy in Response to Viral Infections

Dimeric Structure of Pseudokinase RNase L Bound to 2-5A Reveals a Basis for Interferon-Induced Antiviral Activity

The Effect of Primary Graft Dysfunction on Survival after Lung Transplantation

Analogs of the Catechol Derivative Dynasore Inhibit HIV-1 Ribonuclease H, SARS-CoV-2 nsp14 Exoribonuclease, and Virus Replication

Race and electronically measured adherence to immunosuppressive medications after deceased donor renal transplantation

Impact of Primary Graft Failure on Outcomes Following Lung Transplantation

Integration Site Preference of Xenotropic Murine Leukemia Virus-Related Virus, a New Human Retrovirus Associated with Prostate Cancer

Murine AKAP7 has a 2',5'-phosphodiesterase domain that can complement an inactive murine coronavirus ns2 gene

In-depth investigation of archival and prospectively collected samples reveals no evidence for XMRV infection in prostate cancer

Fibrils of Prostatic Acid Phosphatase Fragments Boost Infections with XMRV (Xenotropic Murine Leukemia Virus-Related Virus), a Human Retrovirus Associated with Prostate Cancer

Infection, Viral Dissemination, and Antibody Responses of Rhesus Macaques Exposed to the Human Gammaretrovirus XMRV

Absence of XMRV and closely related viruses in primary prostate cancer tissues used to derive the XMRV-infected cell line 22Rv1

Identification of Small Molecule Inhibitors of RNase L by Fragment-Based Drug Discovery

Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication

Suppressing PAR ylation by 2′,5′‐oligoadenylate synthetase 1 inhibits DNA damage‐induced cell death

Suppressing PARylation by 2′,5′‐oligoadenylate synthetase 1 inhibits DNA damage‐induced cell death

Suppressing PAR ylation by 2′,5′‐oligoadenylate synthetase 1 inhibits DNA damage‐induced cell death

A phenolic small molecule inhibitor of RNase L prevents cell death from ADAR1 deficiency

Relationship of Estimated GFR and Coronary Artery Calcification in the CRIC (Chronic Renal Insufficiency Cohort) Study

Suppressing PARylation by 2′,5′‐oligoadenylate synthetase 1 inhibits DNA damage‐induced cell death

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