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Natural Product Libraries to Accelerate the High-Throughput Discovery of Therapeutic Leads

Journal of natural products (Washington, D.C.), 2011-12, Vol.74 (12), p.2545-2555

2011

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Discovery of platelet-type 12-human lipoxygenase selective inhibitors by high-throughput screening of structurally diverse libraries

Bioorganic & medicinal chemistry, 2007-11, Vol.15 (22), p.6900-6908

2007

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Accelerating the Discovery of Biologically Active Small Molecules Using a High-Throughput Yeast Halo Assay

Journal of natural products (Washington, D.C.), 2007-03, Vol.70 (3), p.383-390

2007

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Pyrroloacridine Alkaloids from Plakortis quasiamphiaster: Structures and Bioactivity

Journal of natural products (Washington, D.C.), 2007-01, Vol.70 (1), p.95-99

2007

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A β-Carboline Alkaloid from the Papua New Guinea Marine Sponge Hyrtios reticulatus

Journal of natural products (Washington, D.C.), 2010-02, Vol.73 (2), p.255-257

2010

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Biostructural Features of Additional Jasplakinolide (Jaspamide) Analogues

Journal of natural products (Washington, D.C.), 2011-03, Vol.74 (3), p.341-351

2011

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An image-based 384-well high-throughput screening method for the discovery of biofilm inhibitors in Vibrio cholerae

Molecular bioSystems, 2011-04, Vol.7 (4), p.1176-1184

2011

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New Structures and Bioactivity Properties of Jasplakinolide (Jaspamide) Analogues from Marine Sponges

Journal of medicinal chemistry, 2010-02, Vol.53 (4), p.1651-1661

2010

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The C-Terminal Fragment of the Precursor Tail Lysozyme of Bacteriophage T4 Stays as a Structural Component of the Baseplate after Cleavage

Journal of Bacteriology, 1999-05, Vol.181 (9), p.2739-2744

1999

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Pinpointing Pseurotins from a Marine-Derived Aspergillus as Tools for Chemical Genetics Using a Synthetic Lethality Yeast Screen

Journal of natural products (Washington, D.C.), 2007-10, Vol.70 (10), p.1672-1675

2007

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Multiple methionine substitutions are tolerated in T4 lysozyme and have coupled effects on folding and stability

Biophysical chemistry, 2003-01, Vol.100 (1-3), p.325-340

2003

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A Test of the ``Jigsaw Puzzle" Model for Protein Folding by Multiple Methionine Substitutions within the Core of T4 Lysozyme

Proceedings of the National Academy of Sciences - PNAS, 1996-10, Vol.93 (22), p.12155-12158

1996

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HALO384: A Halo-Based Potency Prediction Algorithm for High-Throughput Detection of Antimicrobial Agents

Journal of biomolecular screening, 2010-02, Vol.15 (2), p.196-205

2010

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Methionine and Alanine Substitutions Show That the Formation of Wild-Type-like Structure in the Carboxy-Terminal Domain of T4 Lysozyme Is a Rate-Limiting Step in Folding

Biochemistry (Easton), 1999-11, Vol.38 (44), p.14451-14460

1999

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A b-Carboline Alkaloid from the Papua New Guinea Marine Sponge Hyrtios reticulatus

Journal of natural products (Washington, D.C.), 2009-12, Vol.73 (2), p.255-257

2009

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Use of differentially substituted selenomethionine proteins in X-ray structure determination

Acta crystallographica. Section D, Biological crystallography., 1999-12, Vol.55 (12), p.1967-1970

1999

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The enthalpy of transfer of unfolded proteins into solutions of urea and guanidinium chloride

Biophysical chemistry, 1996-04, Vol.59 (3), p.259-275

1996

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Substitution with selenomethionine can enhance the stability of methionine-rich proteins

Journal of molecular biology, 1999-11, Vol.294 (1), p.17-20

1999

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Context‐dependent protein stabilization by methionine‐to‐leucine substitution shown in T4 lysozyme

Protein science, 1998-03, Vol.7 (3), p.765-773

1998

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Substitution with selenomethionine can enhance the stability of methionine-rich proteins 1 1Edited by B. Honig

Journal of molecular biology, 1999-11, Vol.294 (1), p.17-20

1999

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Context‐dependent protein stabilization by methionine‐to‐leucine substitution shown in T4 lysozyme

Protein science, 1998-06, Vol.7 (6), p.1481-1481

1998

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Isolation and characterization of multiple-methionine mutants of T4 lysozyme with simplified cores

Techniques in Protein Chemistry, 1997, Vol.8, p.851-863

1997

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MNSs genotyping by MALDI‐TOF MS shows high concordance with serology, allows gene copy number testing and reveals new St(a) alleles

British journal of haematology, 2016-08, Vol.174 (4), p.624-636

2016

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MNS s genotyping by MALDI ‐ TOF MS shows high concordance with serology, allows gene copy number testing and reveals new St(a) alleles

British journal of haematology, 2016-08, Vol.174 (4), p.624-636

2016

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Low-Frequency Blood Group Antigens in Switzerland

Transfusion medicine and hemotherapy, 2018-07, Vol.45 (4), p.239-250

2018

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Natural Product Libraries to Accelerate the High-Throughput Discovery of Therapeutic Leads

Discovery of platelet-type 12-human lipoxygenase selective inhibitors by high-throughput screening of structurally diverse libraries

Accelerating the Discovery of Biologically Active Small Molecules Using a High-Throughput Yeast Halo Assay

Pyrroloacridine Alkaloids from Plakortis quasiamphiaster: Structures and Bioactivity

A β-Carboline Alkaloid from the Papua New Guinea Marine Sponge Hyrtios reticulatus

Biostructural Features of Additional Jasplakinolide (Jaspamide) Analogues

An image-based 384-well high-throughput screening method for the discovery of biofilm inhibitors in Vibrio cholerae

New Structures and Bioactivity Properties of Jasplakinolide (Jaspamide) Analogues from Marine Sponges

The C-Terminal Fragment of the Precursor Tail Lysozyme of Bacteriophage T4 Stays as a Structural Component of the Baseplate after Cleavage

Pinpointing Pseurotins from a Marine-Derived Aspergillus as Tools for Chemical Genetics Using a Synthetic Lethality Yeast Screen

Multiple methionine substitutions are tolerated in T4 lysozyme and have coupled effects on folding and stability

A Test of the ``Jigsaw Puzzle" Model for Protein Folding by Multiple Methionine Substitutions within the Core of T4 Lysozyme

HALO384: A Halo-Based Potency Prediction Algorithm for High-Throughput Detection of Antimicrobial Agents

Methionine and Alanine Substitutions Show That the Formation of Wild-Type-like Structure in the Carboxy-Terminal Domain of T4 Lysozyme Is a Rate-Limiting Step in Folding

A b-Carboline Alkaloid from the Papua New Guinea Marine Sponge Hyrtios reticulatus

Use of differentially substituted selenomethionine proteins in X-ray structure determination

The enthalpy of transfer of unfolded proteins into solutions of urea and guanidinium chloride

Substitution with selenomethionine can enhance the stability of methionine-rich proteins

Context‐dependent protein stabilization by methionine‐to‐leucine substitution shown in T4 lysozyme

Substitution with selenomethionine can enhance the stability of methionine-rich proteins 1 1Edited by B. Honig

Context‐dependent protein stabilization by methionine‐to‐leucine substitution shown in T4 lysozyme

Isolation and characterization of multiple-methionine mutants of T4 lysozyme with simplified cores

MNSs genotyping by MALDI‐TOF MS shows high concordance with serology, allows gene copy number testing and reveals new St(a) alleles

MNS s genotyping by MALDI ‐ TOF MS shows high concordance with serology, allows gene copy number testing and reveals new St(a) alleles

Low-Frequency Blood Group Antigens in Switzerland

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