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Genome-wide mapping of mutations at single-nucleotide resolution for protein, metabolic and genome engineering

Nature biotechnology, 2017-01, Vol.35 (1), p.48-55

2017

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Small molecule regulated sgRNAs enable control of genome editing in E. coli by Cas9

Nature communications, 2020-03, Vol.11 (1), p.1394-1394, Article 1394

2020

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Deep scanning lysine metabolism in Escherichia coli

Molecular systems biology, 2018-11, Vol.14 (11), p.e8371-n/a

2018

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Crystal Structure of the Lysine Riboswitch Regulatory mRNA Element

The Journal of biological chemistry, 2008-08, Vol.283 (33), p.22347-22351

2008

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A switch in time: Detailing the life of a riboswitch

Biochimica et biophysica acta, 2009-09, Vol.1789 (9), p.584-591

2009

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Multiplexed tracking of combinatorial genomic mutations in engineered cell populations

Nature biotechnology, 2015-06, Vol.33 (6), p.631-637

2015

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Modularity of Select Riboswitch Expression Platforms Enables Facile Engineering of Novel Genetic Regulatory Devices

ACS synthetic biology, 2013-08, Vol.2 (8), p.463-472

2013

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Photoperiod and food restriction differentially affect reproductive and immune responses in Siberian hamsters Phodopus sungorus

Functional ecology, 2009-10, Vol.23 (5), p.979-988

2009

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Riboswitches: structures and mechanisms

Cold Spring Harbor perspectives in biology, 2011-06, Vol.3 (6), p.a003533-a003533

2011

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Integrating CRISPR-Enabled Trackable Genome Engineering and Transcriptomic Analysis of Global Regulators for Antibiotic Resistance Selection and Identification in Escherichia coli

mSystems, 2020-04, Vol.5 (2)

2020

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Iterative genome editing of Escherichia coli for 3-hydroxypropionic acid production

Metabolic engineering, 2018-05, Vol.47 (C), p.303-313

2018

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CRISPR EnAbled Trackable genome Engineering for isopropanol production in Escherichia coli

Metabolic engineering, 2017-05, Vol.41 (C), p.1-10

2017

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Multiplex navigation of global regulatory networks (MINR) in yeast for improved ethanol tolerance and production

Metabolic engineering, 2019-01, Vol.51, p.50-58

2019

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Rapid and Efficient One-Step Metabolic Pathway Integration in E. coli

ACS synthetic biology, 2016-07, Vol.5 (7), p.561-568

2016

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Directed combinatorial mutagenesis of Escherichia coli for complex phenotype engineering

Metabolic engineering, 2018-05, Vol.47 (C), p.10-20

2018

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Insights into the Regulatory Landscape of the Lysine Riboswitch

Journal of molecular biology, 2012-10, Vol.423 (1), p.17-33

2012

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Single-Molecule Studies of the Lysine Riboswitch Reveal Effector-Dependent Conformational Dynamics of the Aptamer Domain

Biochemistry (Easton), 2012-11, Vol.51 (45), p.9223-9233

2012

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Codon Compression Algorithms for Saturation Mutagenesis

ACS synthetic biology, 2015-05, Vol.4 (5), p.604-614

2015

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Discrimination between Closely Related Cellular Metabolites by the SAM-I Riboswitch

Journal of molecular biology, 2010-02, Vol.396 (3), p.761-772

2010

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Genomic Deoxyxylulose Phosphate Reductoisomerase (DXR) Mutations Conferring Resistance to the Antimalarial Drug Fosmidomycin in E. coli

ACS synthetic biology, 2018-12, Vol.7 (12), p.2824-2832

2018

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The emergence of commodity-scale genetic manipulation

Current opinion in chemical biology, 2015-10, Vol.28, p.150-155

2015

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Determining structures of RNA aptamers and riboswitches by X-ray crystallography

Methods in molecular biology (Clifton, N.J.), 2009, Vol.535, p.135

2009

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Genome-Wide Tuning of Protein Expression Levels to Rapidly Engineer Microbial Traits

ACS synthetic biology, 2015-11, Vol.4 (11), p.1244-1253

2015

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Strategies in RNA Crystallography

Methods in Enzymology, 2009, Vol.469, p.119-139

2009

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Multiplex Navigation of Global Regulatory Networks (MINR) in yeast for Improved Ethanol Tolerance and Production

Metabolic engineering, 2018-07, Vol.51

2018

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Genome-wide mapping of mutations at single-nucleotide resolution for protein, metabolic and genome engineering

Small molecule regulated sgRNAs enable control of genome editing in E. coli by Cas9

Deep scanning lysine metabolism in Escherichia coli

Crystal Structure of the Lysine Riboswitch Regulatory mRNA Element

A switch in time: Detailing the life of a riboswitch

Multiplexed tracking of combinatorial genomic mutations in engineered cell populations

Modularity of Select Riboswitch Expression Platforms Enables Facile Engineering of Novel Genetic Regulatory Devices

Photoperiod and food restriction differentially affect reproductive and immune responses in Siberian hamsters Phodopus sungorus

Riboswitches: structures and mechanisms

Integrating CRISPR-Enabled Trackable Genome Engineering and Transcriptomic Analysis of Global Regulators for Antibiotic Resistance Selection and Identification in Escherichia coli

Iterative genome editing of Escherichia coli for 3-hydroxypropionic acid production

CRISPR EnAbled Trackable genome Engineering for isopropanol production in Escherichia coli

Multiplex navigation of global regulatory networks (MINR) in yeast for improved ethanol tolerance and production

Rapid and Efficient One-Step Metabolic Pathway Integration in E. coli

Directed combinatorial mutagenesis of Escherichia coli for complex phenotype engineering

Insights into the Regulatory Landscape of the Lysine Riboswitch

Single-Molecule Studies of the Lysine Riboswitch Reveal Effector-Dependent Conformational Dynamics of the Aptamer Domain

Codon Compression Algorithms for Saturation Mutagenesis

Discrimination between Closely Related Cellular Metabolites by the SAM-I Riboswitch

Genomic Deoxyxylulose Phosphate Reductoisomerase (DXR) Mutations Conferring Resistance to the Antimalarial Drug Fosmidomycin in E. coli

The emergence of commodity-scale genetic manipulation

Determining structures of RNA aptamers and riboswitches by X-ray crystallography

Genome-Wide Tuning of Protein Expression Levels to Rapidly Engineer Microbial Traits

Strategies in RNA Crystallography

Multiplex Navigation of Global Regulatory Networks (MINR) in yeast for Improved Ethanol Tolerance and Production

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