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Cyclosporine A delivery to the eye: A comprehensive review of academic and industrial efforts

European journal of pharmaceutics and biopharmaceutics, 2017-08, Vol.117, p.14-28

2017

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Benefits of cetalkonium chloride cationic oil-in-water nanoemulsions for topical ophthalmic drug delivery

Journal of pharmacy and pharmacology, 2014-04, Vol.66 (4), p.531-541

2014

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Review of clinical outcomes of a cationic emulsion tear substitute in patients with dry eye disease

Acta ophthalmologica (Oxford, England), 2024-06, Vol.102 (4), p.382-390

2024

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Relevance of Lipid-Based Products in the Management of Dry Eye Disease

Journal of ocular pharmacology and therapeutics, 2017-11, Vol.33 (9), p.647

2017

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Use of a Cationic Emulsion of Latanoprost to Treat Glaucoma Patients with Ocular Surface Disease: A Preclinical Review

Journal of ocular pharmacology and therapeutics, 2023-05, Vol.39 (4), p.240

2023

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Efficacy and safety of 0.1% ciclosporin A cationic emulsion in dry eye disease: a pooled analysis of two double-masked, randomised, vehicle-controlled phase III clinical studies

British journal of ophthalmology, 2019-01, Vol.103 (1), p.125

2019

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A Randomized Study of the Efficacy and Safety of 0.1% Cyclosporine a Cationic Emulsion in Treatment of Moderate to Severe Dry Eye

European journal of ophthalmology, 2017-09, Vol.27 (5), p.520-530

2017

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Ocular surface response of two preservative-free cylcosporine A emulsion eye drops in a mouse model of dry eye

Current eye research, 2021-08, Vol.46 (8), p.1096-1104

2021

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Conjunctival transcriptome analysis reveals the overexpression of multiple pattern recognition receptors in vernal keratoconjunctivitis

The ocular surface, 2021-01, Vol.19, p.241-248

2021

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Tiny dexamethasone palmitate nanoparticles for intravitreal injection: Optimization and in vivo evaluation

International journal of pharmaceutics, 2021-05, Vol.600, p.120509-120509, Article 120509

2021

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Comparison of Two Experimental Mouse Dry Eye Models through Inflammatory Gene Set Enrichment Analysis Based on a Multiplexed Transcriptomic Approach

International journal of molecular sciences, 2021-10, Vol.22 (19), p.10770

2021

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Distribution of cyclosporine A in ocular tissues after topical administration of cyclosporine A cationic emulsions to pigmented rabbits

Cornea, 2013-03, Vol.32 (3), p.345

2013

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One-Year Efficacy and Safety of 0.1% Cyclosporine a Cationic Emulsion in the Treatment of Severe Dry Eye Disease

European journal of ophthalmology, 2017-11, Vol.27 (6), p.678-685

2017

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Conjunctival Inflammatory Gene Expression Profiling in Dry Eye Disease: Correlations With HLA-DRA and HLA-DRB1

Frontiers in immunology, 2018-10, Vol.9, p.2271-2271

2018

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Modulation of Inflammation-Related Genes in the Cornea of a Mouse Model of Dry Eye upon Treatment with Cyclosporine Eye Drops

Current eye research, 2019-05, Vol.44 (5), p.476-485

2019

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Safety and Tolerability of Overdosed Artificial Tears by Abraded Rabbit Corneas

Journal of ocular pharmacology and therapeutics, 2018-12, Vol.34 (10), p.670

2018

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Anti-inflammatory activity of CKC-containing cationic emulsion eye drop vehicles

Molecular vision, 2018-07, Vol.24, p.459-470

2018

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Persistence of Efficacy of 0.1% Cyclosporin A Cationic Emulsion in Subjects with Severe Keratitis Due to Dry Eye Disease: A Nonrandomized, Open-label Extension of the SANSIKA Study

Clinical therapeutics, 2018-11, Vol.40 (11), p.1894-1906

2018

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Comparison of the Anti-Inflammatory Effects of Artificial Tears in a Rat Model of Corneal Scraping

Journal of ocular pharmacology and therapeutics, 2016-03, Vol.32 (2), p.109

2016

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In Vitro Corneal and Conjunctival Wound-Healing Assays as a Tool for Antiglaucoma Prostaglandin Formulation Characterization

Frontiers in bioscience (Landmark. Print), 2022-05, Vol.27 (5), p.147-147

2022

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Efficacy and Safety of a Cationic Emulsion in the Treatment of Moderate to Severe Dry Eye Disease: A Randomized Controlled Study

European journal of ophthalmology, 2016-11, Vol.26 (6), p.546-555

2016

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In vitro and in vivo evaluation of a preservative-free cationic emulsion of latanoprost in corneal wound healing models

Cornea, 2012-11, Vol.31 (11), p.1319

2012

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Ocular safety of cationic emulsion of cyclosporine in an in vitro corneal wound-healing model and an acute in vivo rabbit model

Molecular vision, 2012-08, Vol.18, p.2195-2204

2012

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Antiviral response in vernal keratoconjunctivitis may be protective against COVID‐19

Allergy (Copenhagen), 2022-01, Vol.77 (1), p.298-300

2022

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Correlation between gene expression and clinical scores in vernal keratoconjunctivitis

Allergy (Copenhagen), 2024-02, Vol.79 (2), p.513-515

2024

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Cyclosporine A delivery to the eye: A comprehensive review of academic and industrial efforts

Benefits of cetalkonium chloride cationic oil-in-water nanoemulsions for topical ophthalmic drug delivery

Review of clinical outcomes of a cationic emulsion tear substitute in patients with dry eye disease

Relevance of Lipid-Based Products in the Management of Dry Eye Disease

Use of a Cationic Emulsion of Latanoprost to Treat Glaucoma Patients with Ocular Surface Disease: A Preclinical Review

Efficacy and safety of 0.1% ciclosporin A cationic emulsion in dry eye disease: a pooled analysis of two double-masked, randomised, vehicle-controlled phase III clinical studies

A Randomized Study of the Efficacy and Safety of 0.1% Cyclosporine a Cationic Emulsion in Treatment of Moderate to Severe Dry Eye

Ocular surface response of two preservative-free cylcosporine A emulsion eye drops in a mouse model of dry eye

Conjunctival transcriptome analysis reveals the overexpression of multiple pattern recognition receptors in vernal keratoconjunctivitis

Tiny dexamethasone palmitate nanoparticles for intravitreal injection: Optimization and in vivo evaluation

Comparison of Two Experimental Mouse Dry Eye Models through Inflammatory Gene Set Enrichment Analysis Based on a Multiplexed Transcriptomic Approach

Distribution of cyclosporine A in ocular tissues after topical administration of cyclosporine A cationic emulsions to pigmented rabbits

One-Year Efficacy and Safety of 0.1% Cyclosporine a Cationic Emulsion in the Treatment of Severe Dry Eye Disease

Conjunctival Inflammatory Gene Expression Profiling in Dry Eye Disease: Correlations With HLA-DRA and HLA-DRB1

Modulation of Inflammation-Related Genes in the Cornea of a Mouse Model of Dry Eye upon Treatment with Cyclosporine Eye Drops

Safety and Tolerability of Overdosed Artificial Tears by Abraded Rabbit Corneas

Anti-inflammatory activity of CKC-containing cationic emulsion eye drop vehicles

Persistence of Efficacy of 0.1% Cyclosporin A Cationic Emulsion in Subjects with Severe Keratitis Due to Dry Eye Disease: A Nonrandomized, Open-label Extension of the SANSIKA Study

Comparison of the Anti-Inflammatory Effects of Artificial Tears in a Rat Model of Corneal Scraping

In Vitro Corneal and Conjunctival Wound-Healing Assays as a Tool for Antiglaucoma Prostaglandin Formulation Characterization

Efficacy and Safety of a Cationic Emulsion in the Treatment of Moderate to Severe Dry Eye Disease: A Randomized Controlled Study

In vitro and in vivo evaluation of a preservative-free cationic emulsion of latanoprost in corneal wound healing models

Ocular safety of cationic emulsion of cyclosporine in an in vitro corneal wound-healing model and an acute in vivo rabbit model

Antiviral response in vernal keratoconjunctivitis may be protective against COVID‐19

Correlation between gene expression and clinical scores in vernal keratoconjunctivitis

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