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Pronounced cohabitation of active immunoglobulin genes from three different chromosomes in transcription factories during maximal antibody synthesis

Genes & development, 2014-06, Vol.28 (11), p.1159-1164

2014

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Discovery, regulation, and action of the major apoptotic nucleases DFF40/CAD and endonuclease G

Journal of cellular biochemistry, 2005-04, Vol.94 (6), p.1078-1087

2005

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Long-Range Interactions between Three Transcriptional Enhancers, Active Vκ Gene Promoters, and a 3′ Boundary Sequence Spanning 46 Kilobases

Molecular and Cellular Biology, 2005-04, Vol.25 (8), p.3220-3231

2005

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Loss of an Igκ Gene Enhancer in Mature B Cells Results in Rapid Gene Silencing and Partial Reversible Dedifferentiation

Molecular and Cellular Biology, 2013-05, Vol.33 (10), p.2091-2101

2013

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Assembly and analysis of the mouse immunoglobulin kappa gene sequence

Immunogenetics (New York), 2004-10, Vol.56 (7), p.490-505

2004

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A major deletion in the Vκ-Jκ intervening region results in hyperelevated transcription of proximal Vκ genes and a severely restricted repertoire

The Journal of immunology (1950), 2014-10, Vol.193 (7), p.3746-3754

2014

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Vκ gene repertoire and locus contraction are specified by critical DNase I hypersensitive sites within the Vκ-Jκ intervening region

The Journal of immunology (1950), 2013-02, Vol.190 (4), p.1819-1826

2013

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A multifunctional element in the mouse Igκ locus that specifies repertoire and Ig loci subnuclear location

The Journal of immunology (1950), 2011-05, Vol.186 (9), p.5356-5366

2011

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Subunit Structures and Stoichiometries of Human DNA Fragmentation Factor Proteins before and after Induction of Apoptosis

The Journal of biological chemistry, 2003-07, Vol.278 (29), p.26915-26922

2003

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The Downstream Transcriptional Enhancer, Ed, positively regulates mouse Ig kappa gene expression and somatic hypermutation

The Journal of immunology (1950), 2008-05, Vol.180 (10), p.6725-6732

2008

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The Igκ gene enhancers, E3' and Ed, are essential for triggering transcription

The Journal of immunology (1950), 2010-12, Vol.185 (12), p.7544-7552

2010

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A new hypersensitive site, HS10, and the enhancers, E3' and Ed, differentially regulate Igκ gene expression

The Journal of immunology (1950), 2012-03, Vol.188 (6), p.2722-2732

2012

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The 40-kDa Subunit of DNA Fragmentation Factor Induces DNA Fragmentation and Chromatin Condensation during Apoptosis

Proceedings of the National Academy of Sciences - PNAS, 1998-07, Vol.95 (15), p.8461-8466

1998

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Cleavage Preferences of the Apoptotic Endonuclease DFF40 (Caspase-activated DNase or Nuclease) on Naked DNA and Chromatin Substrates

The Journal of biological chemistry, 2000-03, Vol.275 (11), p.8226-8232

2000

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The Histone H1 C-Terminal Domain Binds to the Apoptotic Nuclease, DNA Fragmentation Factor (DFF40/CAD) and Stimulates DNA Cleavage

Biochemistry (Easton), 2005-05, Vol.44 (21), p.7871-7878

2005

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A Recombination Silencer that Specifies Heterochromatin Positioning and Ikaros Association in the Immunoglobulin κ Locus

Immunity (Cambridge, Mass.), 2006-04, Vol.24 (4), p.405-415

2006

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Unique features of the apoptotic endonuclease DFF40/CAD relative to micrococcal nuclease as a structural probe for chromatin

Biochemistry and cell biology, 2006-08, Vol.84 (4), p.405

2006

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The apoptotic endonuclease DFF40/CAD is inhibited by RNA, heparin and other polyanions

Apoptosis (London), 2006-08, Vol.11 (8), p.1331-1337

2006

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Engineered apoptotic nucleases for chromatin research

Nucleic acids research, 2007-07, Vol.35 (13), p.e93-e93

2007

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Modeling apoptotic chromatin condensation in normal cell nuclei. Requirement for intranuclear mobility and actin involvement

The Journal of biological chemistry, 2002-06, Vol.277 (24), p.21683-21690

2002

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Unique features of the apoptotic endonuclease DFF40/CAD relative to micrococcal nuclease as a structural probe for chromatinThis paper is one of a selection of papers published in this Special Issue, entitled 27th International West Coast Chromatin and Chromosome Conference, and has undergone the Journal's usual peer review process

Biochemistry and cell biology, 2006-08, Vol.84 (4), p.405-410

2006

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The kinetics of V–J joining throughout 3.5 megabases of the mouse Igκ locus fit a constrained diffusion model of nuclear organization

FEBS letters, 2003-02, Vol.536 (1), p.125-129

2003

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Yeast Artificial Chromosome Contigs Reveal that Distal Variable-Region Genes Reside at Least 3 Megabases from the Joining Regions in the Murine Immunoglobulin κ Locus

Proceedings of the National Academy of Sciences - PNAS, 1995-12, Vol.92 (26), p.12421-12425

1995

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Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer in a region containing topoisomerase II sites

Cell, 1986-01, Vol.44 (2), p.273-282

1986

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Yeast Calmodulin and a Conserved Nuclear Protein Participate in the in vivo Binding of a Matrix Association Region

Proceedings of the National Academy of Sciences - PNAS, 1993-06, Vol.90 (12), p.5623-5627

1993

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Pronounced cohabitation of active immunoglobulin genes from three different chromosomes in transcription factories during maximal antibody synthesis

Discovery, regulation, and action of the major apoptotic nucleases DFF40/CAD and endonuclease G

Long-Range Interactions between Three Transcriptional Enhancers, Active Vκ Gene Promoters, and a 3′ Boundary Sequence Spanning 46 Kilobases

Loss of an Igκ Gene Enhancer in Mature B Cells Results in Rapid Gene Silencing and Partial Reversible Dedifferentiation

Assembly and analysis of the mouse immunoglobulin kappa gene sequence

A major deletion in the Vκ-Jκ intervening region results in hyperelevated transcription of proximal Vκ genes and a severely restricted repertoire

Vκ gene repertoire and locus contraction are specified by critical DNase I hypersensitive sites within the Vκ-Jκ intervening region

A multifunctional element in the mouse Igκ locus that specifies repertoire and Ig loci subnuclear location

Subunit Structures and Stoichiometries of Human DNA Fragmentation Factor Proteins before and after Induction of Apoptosis

The Downstream Transcriptional Enhancer, Ed, positively regulates mouse Ig kappa gene expression and somatic hypermutation

The Igκ gene enhancers, E3' and Ed, are essential for triggering transcription

A new hypersensitive site, HS10, and the enhancers, E3' and Ed, differentially regulate Igκ gene expression

The 40-kDa Subunit of DNA Fragmentation Factor Induces DNA Fragmentation and Chromatin Condensation during Apoptosis

Cleavage Preferences of the Apoptotic Endonuclease DFF40 (Caspase-activated DNase or Nuclease) on Naked DNA and Chromatin Substrates

The Histone H1 C-Terminal Domain Binds to the Apoptotic Nuclease, DNA Fragmentation Factor (DFF40/CAD) and Stimulates DNA Cleavage

A Recombination Silencer that Specifies Heterochromatin Positioning and Ikaros Association in the Immunoglobulin κ Locus

Unique features of the apoptotic endonuclease DFF40/CAD relative to micrococcal nuclease as a structural probe for chromatin

The apoptotic endonuclease DFF40/CAD is inhibited by RNA, heparin and other polyanions

Engineered apoptotic nucleases for chromatin research

Modeling apoptotic chromatin condensation in normal cell nuclei. Requirement for intranuclear mobility and actin involvement

The kinetics of V–J joining throughout 3.5 megabases of the mouse Igκ locus fit a constrained diffusion model of nuclear organization

Yeast Artificial Chromosome Contigs Reveal that Distal Variable-Region Genes Reside at Least 3 Megabases from the Joining Regions in the Murine Immunoglobulin κ Locus

Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer in a region containing topoisomerase II sites

Yeast Calmodulin and a Conserved Nuclear Protein Participate in the in vivo Binding of a Matrix Association Region

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