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Design, execution, and analysis of pooled in vitro CRISPR/Cas9 screens

The FEBS journal, 2016-09, Vol.283 (17), p.3170-3180

2016

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RABiT-III: an Automated Micronucleus Assay at a Non-Specialized Biodosimetry Facility

Radiation research, 2024-06, Vol.201 (6), p.567

2024

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Using CRISPR/Cas to study gene function and model disease in vivo

The FEBS journal, 2016-09, Vol.283 (17), p.3194-3203

2016

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Prediction of potent shRNAs with a sequential classification algorithm

Nature biotechnology, 2017-04, Vol.35 (4), p.350-353

2017

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Selective Elimination of Human Pluripotent Stem Cells by an Oleate Synthesis Inhibitor Discovered in a High-Throughput Screen

Cell stem cell, 2013-02, Vol.12 (2), p.167-179

2013

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Kinase Regulation of Human MHC Class I Molecule Expression on Cancer Cells

Cancer immunology research, 2016-11, Vol.4 (11), p.936-947

2016

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Microenvironment-derived factors driving metastatic plasticity in melanoma

Nature communications, 2017-02, Vol.8 (1), p.14343-14343, Article 14343

2017

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Cavβ1 regulates T cell expansion and apoptosis independently of voltage-gated Ca2+ channel function

Nature communications, 2022-04, Vol.13 (1), p.2033-19, Article 2033

2022

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A decision process for drug discovery in retinoblastoma

Investigational new drugs, 2021-04, Vol.39 (2), p.426-441

2021

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TP53 mutations and RNA-binding protein MUSASHI-2 drive resistance to PRMT5-targeted therapy in B-cell lymphoma

Nature communications, 2022-09, Vol.13 (1), p.5676-18, Article 5676

2022

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Impact of RNA-guided technologies for target identification and deconvolution

Journal of biomolecular screening, 2014-12, Vol.19 (10), p.1327-1337

2014

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A pharmaceutical company user's perspective on the potential of high content screening in drug discovery

Methods in molecular biology (Clifton, N.J.), 2007, Vol.356, p.19

2007

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Webinar | CRISPR/Cas9 in drug discovery: Applications in target discovery, validation, and hit screening

Science (American Association for the Advancement of Science), 2016-05, Vol.352 (6286), p.730-730

2016

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High‐Throughput Confocal Microscopy for β‐Arrestin–Green Fluorescent Protein Translocation G Protein‐Coupled Receptor Assays Using the Evotec Opera

Measuring Biological Responses with Automated Microscopy, 2006, Vol.414, p.99-120

2006

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Drugs Targeting the Proteasome and Exportin-1 Synergize to Inhibit Well-Differentiated Liposarcoma Cell Proliferation

Journal of the American College of Surgeons, 2022-11, Vol.235 (5), p.S242-S242

2022

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Genome-scale screens identify JNK-JUN signaling as a barrier for pluripotency exit and endoderm differentiation

Nature genetics, 2019-06, Vol.51 (6), p.999-1010

2019

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Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition

Nature genetics, 2021-05, Vol.53 (5), p.707-718

2021

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TNF-NF-κB-p53 axis restricts in vivo survival of hPSC-derived dopamine neurons

Cell, 2024-07, Vol.187 (14), p.3671-3689.e23

2024

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Combined small-molecule treatment accelerates maturation of human pluripotent stem cell-derived neurons

Nature biotechnology, 2024-01

2024

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Abstract IA28: Integrin-mediated mechano-transduction controls HER2 oncogenic signaling and activation of YAP in breast cancer

Molecular cancer research, 2020-08, Vol.18 (8_Supplement), p.IA28-IA28

2020

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Abstract PR04: Integrin-mediated mechano-transduction controls HER2 oncogenic signaling and activation of YAP in breast cancer

Molecular cancer research, 2020-08, Vol.18 (8_Supplement), p.PR04-PR04

2020

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Author Correction: Combined small-molecule treatment accelerates maturation of human pluripotent stem cell-derived neurons

Nature biotechnology, 2024-05

2024

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Design, execution, and analysis of pooled in vitroCRISPR/Cas9 screens

The FEBS journal, 2016-09, Vol.283 (17), p.3170

2016

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Synthetic Introns Identify the Novel RNA Splicing Factor GPATCH8 As Required for Mis-Splicing Induced By SF3B1 Mutations

Blood, 2023-11, Vol.142 (Supplement 1), p.3-3

2023

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Design, execution, and analysis of pooled in vitro CRISPR/Cas9 screens

RABiT-III: an Automated Micronucleus Assay at a Non-Specialized Biodosimetry Facility

Using CRISPR/Cas to study gene function and model disease in vivo

Prediction of potent shRNAs with a sequential classification algorithm

Selective Elimination of Human Pluripotent Stem Cells by an Oleate Synthesis Inhibitor Discovered in a High-Throughput Screen

Kinase Regulation of Human MHC Class I Molecule Expression on Cancer Cells

Microenvironment-derived factors driving metastatic plasticity in melanoma

Cavβ1 regulates T cell expansion and apoptosis independently of voltage-gated Ca2+ channel function

A decision process for drug discovery in retinoblastoma

TP53 mutations and RNA-binding protein MUSASHI-2 drive resistance to PRMT5-targeted therapy in B-cell lymphoma

Clinical, Genomic, and Pharmacological Study of MYCN-Amplified RB1 Wild-Type Metastatic Retinoblastoma

Impact of RNA-guided technologies for target identification and deconvolution

A pharmaceutical company user's perspective on the potential of high content screening in drug discovery

Webinar | CRISPR/Cas9 in drug discovery: Applications in target discovery, validation, and hit screening

High‐Throughput Confocal Microscopy for β‐Arrestin–Green Fluorescent Protein Translocation G Protein‐Coupled Receptor Assays Using the Evotec Opera

Drugs Targeting the Proteasome and Exportin-1 Synergize to Inhibit Well-Differentiated Liposarcoma Cell Proliferation

Genome-scale screens identify JNK-JUN signaling as a barrier for pluripotency exit and endoderm differentiation

Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition

TNF-NF-κB-p53 axis restricts in vivo survival of hPSC-derived dopamine neurons

Combined small-molecule treatment accelerates maturation of human pluripotent stem cell-derived neurons

Abstract IA28: Integrin-mediated mechano-transduction controls HER2 oncogenic signaling and activation of YAP in breast cancer

Abstract PR04: Integrin-mediated mechano-transduction controls HER2 oncogenic signaling and activation of YAP in breast cancer

Author Correction: Combined small-molecule treatment accelerates maturation of human pluripotent stem cell-derived neurons

Design, execution, and analysis of pooled in vitroCRISPR/Cas9 screens

Synthetic Introns Identify the Novel RNA Splicing Factor GPATCH8 As Required for Mis-Splicing Induced By SF3B1 Mutations

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