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Multiple Site Hydrogen Isotope Labelling of Pharmaceuticals

Angewandte Chemie International Edition, 2020-11, Vol.59 (47), p.21114-21120

International ed. in English, 2020

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Efficient Access to Deuterated and Tritiated Nucleobase Pharmaceuticals and Oligonucleotides using Hydrogen‐Isotope Exchange

Angewandte Chemie (International ed.), 2019-04, Vol.58 (15), p.4891-4895

International ed. in English, 2019

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Hydrogen Isotope Exchange Catalyzed by Ru Nanocatalysts: Labelling of Complex Molecules Containing N‐Heterocycles and Reaction Mechanism Insights

Chemistry : a European journal, 2020-04, Vol.26 (22), p.4988-4996

2020

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A Polymer Prodrug Strategy to Switch from Intravenous to Subcutaneous Cancer Therapy for Irritant/Vesicant Drugs

Journal of the American Chemical Society, 2022-10, Vol.144 (41), p.18844-18860

2022

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Circulating Lipoproteins: A Trojan Horse Guiding Squalenoylated Drugs to LDL-Accumulating Cancer Cells

Molecular therapy, 2017-07, Vol.25 (7), p.1596-1605

2017

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Delivery of siRNA to Ewing Sarcoma Tumor Xenografted on Mice, Using Hydrogenated Detonation Nanodiamonds: Treatment Efficacy and Tissue Distribution

Nanomaterials (Basel, Switzerland), 2020-03, Vol.10 (3), p.553

2020

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Synthesis of a Functionalizable Water-Soluble Cryptophane-111

Organic letters, 2013-06, Vol.15 (11), p.2866-2868

2013

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Scalable Synthesis of Cryptophane-1.1.1 and its Functionalization

Organic letters, 2010-03, Vol.12 (5), p.960-962

2010

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Squalenoyl adenosine nanoparticles provide neuroprotection after stroke and spinal cord injury

Nature nanotechnology, 2014-12, Vol.9 (12), p.1054-1062

2014

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LIBS analysis of tritium in thin film-type samples

Journal of nuclear materials, 2024-04, Vol.591, p.154924, Article 154924

2024

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Squalenoyl adenosine nanoparticles provide neuroprotection after stroke and spinal cord injury

Nature nanotechnology, 2014-11, Vol.9 (12), p.1054-1062

2014

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Efficient tritiation of the translocator protein (18 kDa) selective ligand DPA-714

Journal of labelled compounds & radiopharmaceuticals, 2015-01, Vol.58 (1), p.1-6

2015

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In Vitro Analysis of the Effects of ITER-Like Tungsten Nanoparticles: Cytotoxicity and Epigenotoxicity in BEAS-2B Cells

Nanomaterials (Basel, Switzerland), 2019-08, Vol.9 (9), p.1233

2019

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Ruthenium-catalyzed hydrogen isotope exchange of C(sp 3 )-H bonds directed by a sulfur atom

Chemical communications (Cambridge, England), 2018, Vol.54 (24), p.2986-2989

2018

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Squalene-Adenosine Nanoparticles: Ligands of Adenosine Receptors or Adenosine Prodrug?

The Journal of pharmacology and experimental therapeutics, 2019-04, Vol.369 (1), p.144

2019

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Monitoring In Vivo Performances of Protein–Drug Conjugates Using Site-Selective Dual Radiolabeling and Ex Vivo Digital Imaging

Journal of medicinal chemistry, 2022-05, Vol.65 (9), p.6953-6968

2022

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A 3D In Vitro Model of the Human Airway Epithelium Exposed to Tritiated Water: Dosimetric Estimate and Cytotoxic Effects

Radiation research, 2021-03, Vol.195 (3), p.265

2021

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Gemcitabine lipid prodrug nanoparticles: Switching the lipid moiety and changing the fate in the bloodstream

International journal of pharmaceutics, 2021-11, Vol.609, p.121076, Article 121076

2021

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Using hydrogen isotope incorporation as a tool to unravel the surfaces of hydrogen-treated nanodiamonds

Nanoscale, 2019-04, Vol.11 (16), p.8027-8036

2019

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"Clickable" Hydrosoluble PEGylated Cryptophane as a Universal Platform for 129Xe Magnetic Resonance Imaging Biosensors

Chemistry : a European journal, 2013-05, Vol.19 (19), p.6089-6093

2013

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Tritium labeling of detonation nanodiamonds

Chemical communications (Cambridge, England), 2014-03, Vol.5 (22), p.2916-2918

2014

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Easy-to-Implement Hydrogen Isotope Exchange for the Labeling of N‑Heterocycles, Alkylkamines, Benzylic Scaffolds, and Pharmaceuticals

JACS Au, 2022-04, Vol.2 (4), p.801-808

2022

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Tungsten (VI) based “molecular puzzle” photoluminescent nanoparticles easily covered with biocompatible natural polysaccharides via direct chelation

Journal of colloid and interface science, 2018-02, Vol.512, p.308-317

2018

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Multiple Site Hydrogen Isotope Labelling of Pharmaceuticals

Angewandte Chemie, 2020-11, Vol.132 (47), p.21300-21306

2020

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A new nanomedicine based on didanosine glycerolipidic prodrug enhances the long term accumulation of drug in a HIV sanctuary

International journal of pharmaceutics, 2011-07, Vol.414 (1), p.285-297

2011

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Multiple Site Hydrogen Isotope Labelling of Pharmaceuticals

Efficient Access to Deuterated and Tritiated Nucleobase Pharmaceuticals and Oligonucleotides using Hydrogen‐Isotope Exchange

Hydrogen Isotope Exchange Catalyzed by Ru Nanocatalysts: Labelling of Complex Molecules Containing N‐Heterocycles and Reaction Mechanism Insights

A Polymer Prodrug Strategy to Switch from Intravenous to Subcutaneous Cancer Therapy for Irritant/Vesicant Drugs

Circulating Lipoproteins: A Trojan Horse Guiding Squalenoylated Drugs to LDL-Accumulating Cancer Cells

Delivery of siRNA to Ewing Sarcoma Tumor Xenografted on Mice, Using Hydrogenated Detonation Nanodiamonds: Treatment Efficacy and Tissue Distribution

Synthesis of a Functionalizable Water-Soluble Cryptophane-111

Scalable Synthesis of Cryptophane-1.1.1 and its Functionalization

Squalenoyl adenosine nanoparticles provide neuroprotection after stroke and spinal cord injury

LIBS analysis of tritium in thin film-type samples

Squalenoyl adenosine nanoparticles provide neuroprotection after stroke and spinal cord injury

Efficient tritiation of the translocator protein (18 kDa) selective ligand DPA-714

In Vitro Analysis of the Effects of ITER-Like Tungsten Nanoparticles: Cytotoxicity and Epigenotoxicity in BEAS-2B Cells

Ruthenium-catalyzed hydrogen isotope exchange of C(sp 3 )-H bonds directed by a sulfur atom

Squalene-Adenosine Nanoparticles: Ligands of Adenosine Receptors or Adenosine Prodrug?

Monitoring In Vivo Performances of Protein–Drug Conjugates Using Site-Selective Dual Radiolabeling and Ex Vivo Digital Imaging

A 3D In Vitro Model of the Human Airway Epithelium Exposed to Tritiated Water: Dosimetric Estimate and Cytotoxic Effects

Gemcitabine lipid prodrug nanoparticles: Switching the lipid moiety and changing the fate in the bloodstream

Using hydrogen isotope incorporation as a tool to unravel the surfaces of hydrogen-treated nanodiamonds

"Clickable" Hydrosoluble PEGylated Cryptophane as a Universal Platform for 129Xe Magnetic Resonance Imaging Biosensors

Tritium labeling of detonation nanodiamonds

Easy-to-Implement Hydrogen Isotope Exchange for the Labeling of N‑Heterocycles, Alkylkamines, Benzylic Scaffolds, and Pharmaceuticals

Tungsten (VI) based “molecular puzzle” photoluminescent nanoparticles easily covered with biocompatible natural polysaccharides via direct chelation

Multiple Site Hydrogen Isotope Labelling of Pharmaceuticals

A new nanomedicine based on didanosine glycerolipidic prodrug enhances the long term accumulation of drug in a HIV sanctuary

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