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Developmental and Nutritional Dynamics of Malpighian Tubule Autofluorescence in the Asian Tiger Mosquito Aedes albopictus

International journal of molecular sciences, 2023-12, Vol.25 (1), p.245

2023

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Synthesis and Antiviral Activity of Novel 1,3,4-Thiadiazole Inhibitors of DDX3X

Molecules (Basel, Switzerland), 2019-11, Vol.24 (21), p.3988

2019

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Novel Insights into the Biochemical Mechanism of CK1ε and its Functional Interplay with DDX3X

International journal of molecular sciences, 2020-09, Vol.21 (17), p.6449

2020

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A motif unique to the human DEAD-box protein DDX3 is important for nucleic acid binding, ATP hydrolysis, RNA/DNA unwinding and HIV-1 replication

PloS one, 2011-05, Vol.6 (5), p.e19810-e19810

2011

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Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: Towards the next generation HIV-1 inhibitors

Bioorganic & medicinal chemistry letters, 2012-03, Vol.22 (5), p.2094-2098

2012

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A Role for Human DNA Polymerase λ in Alternative Lengthening of Telomeres

International journal of molecular sciences, 2021-03, Vol.22 (5), p.2365

2021

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Exploiting the nucleotide substrate specificity of repair DNA polymerases to develop novel anticancer agents

Molecules, 2011-09, Vol.16 (9), p.7994-8019

2011

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The power of enzyme kinetics in the drug development process

Current pharmaceutical biotechnology, 2013-06, Vol.14 (5), p.551-560

2013

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The PDZ-ligand and Src-homology type 3 domains of epidemic avian influenza virus NS1 protein modulate human Src kinase activity during viral infection

PloS one, 2011-11, Vol.6 (11), p.e27789-e27789

2011

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Homology Model-Based Virtual Screening for the Identification of Human Helicase DDX3 Inhibitors

Journal of chemical information and modeling, 2015-11, Vol.55 (11), p.2443-2454

2015

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DEAD-Box RNA Helicases DDX3X and DDX5 as Oncogenes or Oncosuppressors: A Network Perspective

Cancers, 2022-08, Vol.14 (15), p.3820

2022

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How to win the HIV-1 drug resistance hurdle race: running faster or jumping higher?

Biochemical journal, 2017-05, Vol.474 (10), p.1559-1577

2017

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Developmental and Nutritional Dynamics of Malpighian Tubule Autofluorescence in the Asian Tiger Mosquito IAedes albopictus/I

International journal of molecular sciences, 2023-12, Vol.25 (1)

2023

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DDX3X Helicase Inhibitors as a New Strategy To Fight the West Nile Virus Infection

Journal of medicinal chemistry, 2019-03, Vol.62 (5), p.2333-2347

2019

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Synergistic action of human RNaseH2 and the RNA helicase-nuclease DDX3X in processing R-loops

Nucleic acids research, 2024-08, Vol.52 (19), p.11641-11658

2024

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DDX3X inhibitors, an effective way to overcome HIV-1 resistance targeting host proteins

European journal of medicinal chemistry, 2020-08, Vol.200, p.112319-112319, Article 112319

2020

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Novel alternative ribonucleotide excision repair pathways in human cells by DDX3X and specialized DNA polymerases

Nucleic acids research, 2020-11, Vol.48 (20), p.11551-11565

2020

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Human helicase DDX3 as target for broad-spectrum antivirals against pandemic and emerging viruses

Journal of Virus Eradication, 2016-05, Vol.2, p.38-38

2016

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Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents

Proceedings of the National Academy of Sciences - PNAS, 2016-05, Vol.113 (19), p.5388-5393

2016

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Next generation of antiretroviral agents targeting the RNA binding site of the HIV-1 cellular cofactor DDX3: an innovative therapeutic approach

Retrovirology, 2012-05, Vol.9 (S1), p.P5-P5, Article P5

2012

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Inhibitors of human immunodeficiency virus-1 replication targeting the human DEAD-box polypeptide 3 (DDX3) RNA helicase

Retrovirology, 2010-05, Vol.7 (S1), p.O16-O16, Article O16

2010

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Unique Domain for a Unique Target: Selective Inhibitors of Host Cell DDX3X to Fight Emerging Viruses

Journal of medicinal chemistry, 2020-09, Vol.63 (17), p.9876-9887

2020

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Arabidopsis STRESS RESPONSE SUPPRESSOR DEAD‐box RNA helicases are nucleolar‐ and chromocenter‐localized proteins that undergo stress‐mediated relocalization and are involved in epigenetic gene silencing

The Plant journal : for cell and molecular biology, 2014-07, Vol.79 (1), p.28-43

2014

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Pharmacophore Modeling and Molecular Docking Led to the Discovery of Inhibitors of Human Immunodeficiency Virus-1 Replication Targeting the Human Cellular Aspartic Acid−Glutamic Acid−Alanine−Aspartic Acid Box Polypeptide 3

Journal of medicinal chemistry, 2008-11, Vol.51 (21), p.6635-6638

2008

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Exploring the Implication of DDX3X in DENV Infection: Discovery of the First-in-Class DDX3X Fluorescent Inhibitor

ACS medicinal chemistry letters, 2020-05, Vol.11 (5), p.956-962

2020

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Developmental and Nutritional Dynamics of Malpighian Tubule Autofluorescence in the Asian Tiger Mosquito Aedes albopictus

Synthesis and Antiviral Activity of Novel 1,3,4-Thiadiazole Inhibitors of DDX3X

Novel Insights into the Biochemical Mechanism of CK1ε and its Functional Interplay with DDX3X

A motif unique to the human DEAD-box protein DDX3 is important for nucleic acid binding, ATP hydrolysis, RNA/DNA unwinding and HIV-1 replication

Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: Towards the next generation HIV-1 inhibitors

A Role for Human DNA Polymerase λ in Alternative Lengthening of Telomeres

Exploiting the nucleotide substrate specificity of repair DNA polymerases to develop novel anticancer agents

The power of enzyme kinetics in the drug development process

The PDZ-ligand and Src-homology type 3 domains of epidemic avian influenza virus NS1 protein modulate human Src kinase activity during viral infection

Homology Model-Based Virtual Screening for the Identification of Human Helicase DDX3 Inhibitors

DEAD-Box RNA Helicases DDX3X and DDX5 as Oncogenes or Oncosuppressors: A Network Perspective

How to win the HIV-1 drug resistance hurdle race: running faster or jumping higher?

Developmental and Nutritional Dynamics of Malpighian Tubule Autofluorescence in the Asian Tiger Mosquito IAedes albopictus/I

DDX3X Helicase Inhibitors as a New Strategy To Fight the West Nile Virus Infection

Synergistic action of human RNaseH2 and the RNA helicase-nuclease DDX3X in processing R-loops

DDX3X inhibitors, an effective way to overcome HIV-1 resistance targeting host proteins

Novel alternative ribonucleotide excision repair pathways in human cells by DDX3X and specialized DNA polymerases

Human helicase DDX3 as target for broad-spectrum antivirals against pandemic and emerging viruses

Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents

Next generation of antiretroviral agents targeting the RNA binding site of the HIV-1 cellular cofactor DDX3: an innovative therapeutic approach

Inhibitors of human immunodeficiency virus-1 replication targeting the human DEAD-box polypeptide 3 (DDX3) RNA helicase

Unique Domain for a Unique Target: Selective Inhibitors of Host Cell DDX3X to Fight Emerging Viruses

Arabidopsis STRESS RESPONSE SUPPRESSOR DEAD‐box RNA helicases are nucleolar‐ and chromocenter‐localized proteins that undergo stress‐mediated relocalization and are involved in epigenetic gene silencing

Pharmacophore Modeling and Molecular Docking Led to the Discovery of Inhibitors of Human Immunodeficiency Virus-1 Replication Targeting the Human Cellular Aspartic Acid−Glutamic Acid−Alanine−Aspartic Acid Box Polypeptide 3

Exploring the Implication of DDX3X in DENV Infection: Discovery of the First-in-Class DDX3X Fluorescent Inhibitor

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