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(-)-Naringenin 4',7-dimethyl Ether Isolated from Nardostachys jatamansi Relieves Pain through Inhibition of Multiple Channels

Molecules (Basel, Switzerland), 2022-03, Vol.27 (5), p.1735

2022

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Discovery of SARS-CoV-2-E channel inhibitors as antiviral candidates

Acta pharmacologica Sinica, 2022-04, Vol.43 (4), p.781-787

2022

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Identification and Evaluation of Antiepileptic Activity of C21 Steroidal Glycosides from the Roots of Cynanchum wilfordii

Journal of natural products (Washington, D.C.), 2016-01, Vol.79 (1), p.89-97

2016

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Inhibitory effects of lappaconitine on the neuronal isoforms of voltage-gated sodium channels

Acta pharmacologica Sinica, 2019-04, Vol.40 (4), p.451-459

2019

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Antiepileptic geissoschizine methyl ether is an inhibitor of multiple neuronal channels

Acta pharmacologica Sinica, 2020-05, Vol.41 (5), p.629-637

2020

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Ion channels research in the post-genomic era

Acta pharmacologica Sinica, 2016-01, Vol.37 (1), p.1-3

2016

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Discovery of aryl sulfonamide-selective Nav1.7 inhibitors with a highly hydrophobic ethanoanthracene core

Acta pharmacologica Sinica, 2020-03, Vol.41 (3), p.293-302

2020

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Automotive Control: the State of the Art and Perspective: Automotive Control: the State of the Art and Perspective

Zi dong hua xue bao, 2014-03, Vol.39 (4), p.322-346

2014

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Chlorahololides C–F: a new class of potent and selective potassium channel blockers from Chloranthus holostegius

Tetrahedron, 2008-02, Vol.64 (9), p.2027-2034

2008

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Inhibition of excitatory synaptic transmission by trans-resveratrol in rat hippocampus

Brain research, 2006-09, Vol.1111 (1), p.41-47

2006

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Chlorahololides A and B, Two Potent and Selective Blockers of the Potassium Channel Isolated from Chloranthus holostegius

Organic letters, 2007-03, Vol.9 (5), p.903-906

2007

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Novel KCNQ2 channel activators discovered using fluorescence-based and automated patch-clamp- based high-throughput screening techniques

Acta pharmacologica Sinica, 2016-01, Vol.37 (1), p.105-110

2016

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Discovery of HN37 as a Potent and Chemically Stable Antiepileptic Drug Candidate

Journal of medicinal chemistry, 2021-05, Vol.64 (9), p.5816-5837

2021

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SCN8A epileptic encephalopathy mutations display a gain-of-function phenotype and divergent sensitivity to antiepileptic drugs

Acta pharmacologica Sinica, 2022-12, Vol.43 (12), p.3139-3148

2022

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Identification of 2-substituted pyrrolo[1,2-b]pyridazine derivatives as new PARP-1 inhibitors

Bioorganic & medicinal chemistry letters, 2021-01, Vol.31, p.127710-127710, Article 127710

2021

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Identification of methyl (5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-(trifluoromethyl)pyridin-2-yl)carbamate (CYH33) as an orally bioavailable, highly potent, PI3K alpha inhibitor for the treatment of advanced solid tumors

European journal of medicinal chemistry, 2021-01, Vol.209, p.112913-112913, Article 112913

2021

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Discovery of a retigabine derivative that inhibits KCNQ2 potassium channels

Acta pharmacologica Sinica, 2013-10, Vol.34 (10), p.1359-1366

2013

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Development of SV2A Ligands for Epilepsy Treatment: A Review of Levetiracetam, Brivaracetam, and Padsevonil

Neuroscience bulletin, 2024-05, Vol.40 (5), p.594-608

2024

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Functional characterization and in vitro pharmacological rescue of KCNQ2 pore mutations associated with epileptic encephalopathy

Acta pharmacologica Sinica, 2023-08, Vol.44 (8), p.1589-1599

2023

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Naphthylisoquinoline alkaloids, a new structural template inhibitor of Nav1.7 sodium channel

Acta pharmacologica Sinica, 2023-09, Vol.44 (9), p.1768-1776

2023

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Discovery of Novel Retigabine Derivatives as Potent KCNQ4 and KCNQ5 Channel Agonists with Improved Specificity

ACS medicinal chemistry letters, 2019-01, Vol.10 (1), p.27-33

2019

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Prime editing-based gene correction alleviates the hyperexcitable phenotype and seizures of a genetic epilepsy mouse model

Acta pharmacologica Sinica, 2023-11, Vol.44 (11), p.2342-2345

2023

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Enhancing inactivation rather than reducing activation of Nav1.7 channels by a clinically effective analgesic CNV1014802

Acta pharmacologica Sinica, 2018-04, Vol.39 (4), p.587-596

2018

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Chukrasones A and B: Potential Kv1.2 Potassium Channel Blockers with New Skeletons from Chukrasia tabularis

Organic letters, 2012-09, Vol.14 (17), p.4438-4441

2012

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The synthesis and antistaphylococcal activity of N-sulfonaminoethyloxime derivatives of dehydroabietic acid

Bioorganic & medicinal chemistry letters, 2018-06, Vol.28 (10), p.1943-1948

2018

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(-)-Naringenin 4',7-dimethyl Ether Isolated from Nardostachys jatamansi Relieves Pain through Inhibition of Multiple Channels

Discovery of SARS-CoV-2-E channel inhibitors as antiviral candidates

Identification and Evaluation of Antiepileptic Activity of C21 Steroidal Glycosides from the Roots of Cynanchum wilfordii

Inhibitory effects of lappaconitine on the neuronal isoforms of voltage-gated sodium channels

Antiepileptic geissoschizine methyl ether is an inhibitor of multiple neuronal channels

Ion channels research in the post-genomic era

Discovery of aryl sulfonamide-selective Nav1.7 inhibitors with a highly hydrophobic ethanoanthracene core

Automotive Control: the State of the Art and Perspective: Automotive Control: the State of the Art and Perspective

Chlorahololides C–F: a new class of potent and selective potassium channel blockers from Chloranthus holostegius

Inhibition of excitatory synaptic transmission by trans-resveratrol in rat hippocampus

Chlorahololides A and B, Two Potent and Selective Blockers of the Potassium Channel Isolated from Chloranthus holostegius

Novel KCNQ2 channel activators discovered using fluorescence-based and automated patch-clamp- based high-throughput screening techniques

Discovery of HN37 as a Potent and Chemically Stable Antiepileptic Drug Candidate

SCN8A epileptic encephalopathy mutations display a gain-of-function phenotype and divergent sensitivity to antiepileptic drugs

Identification of 2-substituted pyrrolo[1,2-b]pyridazine derivatives as new PARP-1 inhibitors

Identification of methyl (5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-(trifluoromethyl)pyridin-2-yl)carbamate (CYH33) as an orally bioavailable, highly potent, PI3K alpha inhibitor for the treatment of advanced solid tumors

Discovery of a retigabine derivative that inhibits KCNQ2 potassium channels

Development of SV2A Ligands for Epilepsy Treatment: A Review of Levetiracetam, Brivaracetam, and Padsevonil

Functional characterization and in vitro pharmacological rescue of KCNQ2 pore mutations associated with epileptic encephalopathy

Naphthylisoquinoline alkaloids, a new structural template inhibitor of Nav1.7 sodium channel

Discovery of Novel Retigabine Derivatives as Potent KCNQ4 and KCNQ5 Channel Agonists with Improved Specificity

Prime editing-based gene correction alleviates the hyperexcitable phenotype and seizures of a genetic epilepsy mouse model

Enhancing inactivation rather than reducing activation of Nav1.7 channels by a clinically effective analgesic CNV1014802

Chukrasones A and B: Potential Kv1.2 Potassium Channel Blockers with New Skeletons from Chukrasia tabularis

The synthesis and antistaphylococcal activity of N-sulfonaminoethyloxime derivatives of dehydroabietic acid

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