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Efficient precise in vivo base editing in adult dystrophic mice

Nature communications, 2021-06, Vol.12 (1), p.3719-14, Article 3719

2021

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In Vivo Genome Editing Restores Dystrophin Expression and Cardiac Function in Dystrophic Mice

Circulation research, 2017-09, Vol.121 (8), p.923-929

2017

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A novel rabbit model of Duchenne muscular dystrophy generated by CRISPR/Cas9

Disease models & mechanisms, 2018-06, Vol.11 (6)

2018

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Efficacy of BET Bromodomain Inhibition in Kras-Mutant Non―Small Cell Lung Cancer

Clinical cancer research, 2013-11, Vol.19 (22), p.6183-6192

2013

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Automated muscle histopathology analysis using CellProfiler

Skeletal muscle, 2018-10, Vol.8 (1), p.32-32, Article 32

2018

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Development of muscular dystrophy in a CRISPR-engineered mutant rabbit model with frame-disrupting ANO5 mutations

Cell death & disease, 2018-05, Vol.9 (6), p.609, Article 609

2018

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Correction: Development of muscular dystrophy in a CRISPR-engineered mutant rabbit model with frame-disrupting ANO5 mutations

Cell death & disease, 2020-06, Vol.11 (6), p.468-468, Article 468

2020

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Inhibition of Bromodomain and Extra Terminal (BET) Domain Activity Modulates the IL-23R/IL-17 Axis and Suppresses Acute Graft- Versus -Host Disease

Frontiers in oncology, 2021-10, Vol.11, p.760789-760789

2021

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Empower multiplex cell and tissue-specific CRISPR-mediated gene manipulation with self-cleaving ribozymes and tRNA

Nucleic acids research, 2017-03, Vol.45 (5), p.e28

2017

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BEON: A Functional Fluorescence Reporter for Quantification and Enrichment of Adenine Base-Editing Activity

Molecular therapy, 2020-07, Vol.28 (7), p.1696-1705

2020

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Prohibitin Is a Substrate of PRMT5 in T Cells and Is a Potential Therapeutic Target for Acute Graft-Versus-Host Disease

Blood, 2022-11, Vol.140 (Supplement 1), p.10229-10230

2022

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Life-Long AAV-Mediated CRISPR Genome Editing in Dystrophic Heart Improves Cardiomyopathy without Causing Serious Lesions in mdx Mice

Molecular therapy, 2019-08, Vol.27 (8), p.1407-1414

2019

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CRISPR-mediated Genome Editing Restores Dystrophin Expression and Function in mdx Mice

Molecular therapy, 2016-03, Vol.24 (3), p.564-569

2016

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Prohibitin is Upregulated on Donor T cells in Murine Acute Graft-versus-Host Disease and Promotes Th17 Response

The Journal of immunology (1950), 2023-05, Vol.210 (1_Supplement), p.173-173.13

2023

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Bromodomain and Extraterminal (BET) Domain Inhibition with PLX51107 and PLX2853 Improves Survival and Decreases Acute GVHD Severity in Murine Models

Blood, 2019-11, Vol.134 (Supplement_1), p.4429-4429

2019

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Inhibition of Bromodomain and Extraterminal Domain (BET) Proteins Alleviates Chronic Graft- Versus -Host-Disease Via Modulating the CXCR5/CXCL13 Axis

Blood, 2023-11, Vol.142 (Supplement 1), p.2047-2047

2023

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CRISPR/Cas9 Gene Editing of MIR155HG in Primary Human T Cells to Prevent Acute Graft-Versus-Host Disease

The Journal of immunology (1950), 2023-05, Vol.210 (1_Supplement), p.173-173.21

2023

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CRISPR/CAS9 Gene Editing of MIR155HG in Primary Human T Cells to Prevent Acute Graft-Versus-Host Disease

Blood, 2022-11, Vol.140 (Supplement 1), p.10200-10201

2022

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Adeno-Associated Virus-Mediated Delivery of CRISPR for Cardiac Gene Editing in Mice

Journal of visualized experiments, 2018-08 (138)

2018

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CXCR7 Reactivates ERK Signaling to Promote Resistance to EGFR Kinase Inhibitors in NSCLC

Cancer research (Chicago, Ill.), 2019-09, Vol.79 (17), p.4439-4452

2019

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Adeno-Associated Virus-Mediated Delivery of CRISPR for Cardiac Gene Editing in Mice

Journal of visualized experiments, 2018-08 (138)

2018

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PRMT5 promotes STAT-1 mediated T cell inflammatory response and is a therapeutic target for acute graft-versus-host disease

The Journal of immunology (1950), 2020-05, Vol.204 (1_Supplement), p.87-87.24

2020

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20. A Novel Approach in the Treatment of Dystrophic Cardiomyopathy

Molecular therapy, 2016-05, Vol.24, p.S10-S10

2016

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577. Empower Multiplex CRISPR-Mediated Gene Manipulation with Self-Cleaving Ribozymes and tRNA

Molecular therapy, 2016-05, Vol.24, p.S230-S230

2016

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Abstract 2335: DHODH inhibition modulates T cell metabolism reducing GVHD and prevents relapse following allogeneic HCT

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.2335-2335

2022

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Efficient precise in vivo base editing in adult dystrophic mice

In Vivo Genome Editing Restores Dystrophin Expression and Cardiac Function in Dystrophic Mice

A novel rabbit model of Duchenne muscular dystrophy generated by CRISPR/Cas9

Efficacy of BET Bromodomain Inhibition in Kras-Mutant Non―Small Cell Lung Cancer

Automated muscle histopathology analysis using CellProfiler

Development of muscular dystrophy in a CRISPR-engineered mutant rabbit model with frame-disrupting ANO5 mutations

Correction: Development of muscular dystrophy in a CRISPR-engineered mutant rabbit model with frame-disrupting ANO5 mutations

Inhibition of Bromodomain and Extra Terminal (BET) Domain Activity Modulates the IL-23R/IL-17 Axis and Suppresses Acute Graft- Versus -Host Disease

Empower multiplex cell and tissue-specific CRISPR-mediated gene manipulation with self-cleaving ribozymes and tRNA

BEON: A Functional Fluorescence Reporter for Quantification and Enrichment of Adenine Base-Editing Activity

Prohibitin Is a Substrate of PRMT5 in T Cells and Is a Potential Therapeutic Target for Acute Graft-Versus-Host Disease

Life-Long AAV-Mediated CRISPR Genome Editing in Dystrophic Heart Improves Cardiomyopathy without Causing Serious Lesions in mdx Mice

CRISPR-mediated Genome Editing Restores Dystrophin Expression and Function in mdx Mice

Prohibitin is Upregulated on Donor T cells in Murine Acute Graft-versus-Host Disease and Promotes Th17 Response

Bromodomain and Extraterminal (BET) Domain Inhibition with PLX51107 and PLX2853 Improves Survival and Decreases Acute GVHD Severity in Murine Models

Inhibition of Bromodomain and Extraterminal Domain (BET) Proteins Alleviates Chronic Graft- Versus -Host-Disease Via Modulating the CXCR5/CXCL13 Axis

CRISPR/Cas9 Gene Editing of MIR155HG in Primary Human T Cells to Prevent Acute Graft-Versus-Host Disease

CRISPR/CAS9 Gene Editing of MIR155HG in Primary Human T Cells to Prevent Acute Graft-Versus-Host Disease

Adeno-Associated Virus-Mediated Delivery of CRISPR for Cardiac Gene Editing in Mice

CXCR7 Reactivates ERK Signaling to Promote Resistance to EGFR Kinase Inhibitors in NSCLC

Adeno-Associated Virus-Mediated Delivery of CRISPR for Cardiac Gene Editing in Mice

PRMT5 promotes STAT-1 mediated T cell inflammatory response and is a therapeutic target for acute graft-versus-host disease

20. A Novel Approach in the Treatment of Dystrophic Cardiomyopathy

577. Empower Multiplex CRISPR-Mediated Gene Manipulation with Self-Cleaving Ribozymes and tRNA

Abstract 2335: DHODH inhibition modulates T cell metabolism reducing GVHD and prevents relapse following allogeneic HCT

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