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Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies

PloS one, 2021-07, Vol.16 (7), p.e0253364

2021

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Pyrimidone inhibitors targeting Chikungunya Virus nsP3 macrodomain by fragment-based drug design

PloS one, 2021-01, Vol.16 (1), p.e0245013

2021

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Equations for estimating binary mixture toxicity: 3-methyl-2-butanone with a series of electrophiles

PloS one, 2024-07, Vol.19 (7), p.e0306382

2024

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Contribution of amino acids in the active site of dipeptidyl peptidase 4 to the catalytic action of the enzyme

PloS one, 2024-04, Vol.19 (4), p.e0289239-e0289239

2024

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cis-Decalin-containing tetramic acids as inhibitors of insect steroidogenic glutathione S-transferase Noppera-bo

PloS one, 2023-08, Vol.18 (8), p.e0290851-e0290851

2023

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Epigenetic regulation in colorectal cancer: The susceptibility of microRNAs 145, 143 and 133b to DNA demethylation and histone deacetylase inhibitors

PloS one, 2023-08, Vol.18 (8), p.e0289800-e0289800

2023

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The exquisite specificity of human protein arginine methyltransferase 7 (PRMT7) toward Arg-X-Arg sites

PloS one, 2023-05, Vol.18 (5), p.e0285812-e0285812

2023

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Exploring functional and structural features of chemically related natural prenylated hydroquinone and benzoic acid from Piper crassinervium (Piperaceae) on bacterial peroxiredoxin inhibition

PloS one, 2023-02, Vol.18 (2), p.e0281322-e0281322

2023

Volltextzugriff (PDF)

Label-free affinity screening, design and synthesis of inhibitors targeting the Mycobacterium tuberculosis L-alanine dehydrogenase

PloS one, 2022-11, Vol.17 (11), p.e0277670-e0277670

2022

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Effect of the LSD1 inhibitor RN-1 on γ-globin and global gene expression during erythroid differentiation in baboons (Papio anubis)

PloS one, 2023, Vol.18 (12), p.e0289860-e0289860

2023

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The impact of natural products upon modern drug discovery

Current opinion in chemical biology, 2008-06, Vol.12 (3), p.306-317

Ganesan, A

2008

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Binding of omeprazole to protein targets identified by monoclonal antibodies

PloS one, 2020-09, Vol.15 (9), p.e0239464-e0239464

2020

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The ubiquinone synthesis pathway is a promising drug target for Chagas disease

PloS one, 2021-02, Vol.16 (2), p.e0243855-e0243855

2021

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Expression of epigenetic pathway related genes in association with PD-L1, ER/PgR and MLH1 in endometrial carcinoma

PloS one, 2022-02, Vol.17 (2), p.e0264014

2022

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Multitarget Drugs: an Epigenetic Epiphany

ChemMedChem, 2016-06, Vol.11 (12), p.1227-1241

Ganesan, A.

2016

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One-pot three component synthesis of substituted dihydropyrimidinones using fruit juices as biocatalyst and their biological studies

PloS one, 2020-09, Vol.15 (9), p.e0238092-e0238092

2020

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Piperidine scaffold as the novel P2-ligands in cyclopropyl-containing HIV-1 protease inhibitors: Structure-based design, synthesis, biological evaluation and docking study

PloS one, 2020-07, Vol.15 (7), p.e0235483-e0235483

2020

Volltextzugriff (PDF)

Marine sediment-derived Streptomyces bacteria from British Columbia, Canada are a promising microbiota resource for the discovery of antimicrobial natural products

PloS one, 2013-10, Vol.8 (10), p.e77078-e77078

2013

Volltextzugriff (PDF)

Practical spectrophotometric assay for the dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase, a potential antibiotic target

PloS one, 2018-04, Vol.13 (4), p.e0196010-e0196010

2018

Volltextzugriff (PDF)

Epigenetics: the first 25 centuries

Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2018-06, Vol.373 (1748)

Ganesan, A

2018

Volltextzugriff (PDF)

Pharmacological inhibition of polysialyltransferase ST8SiaII modulates tumour cell migration

PloS one, 2013-08, Vol.8 (8), p.e73366

2013

Volltextzugriff (PDF)

Finding Potent Sirt Inhibitor in Coffee: Isolation, Confirmation and Synthesis of Javamide-II (N-Caffeoyltryptophan) as Sirt1/2 Inhibitor

PloS one, 2016-03, Vol.11 (3), p.e0150392-e0150392

2016

Volltextzugriff (PDF)

Scaffold hopping from (5-hydroxymethyl) isophthalates to multisubstituted pyrimidines diminishes binding affinity to the C1 domain of protein kinase C

PloS one, 2018-04, Vol.13 (4), p.e0195668-e0195668

2018

Volltextzugriff (PDF)

Synthesis of New Styrylquinoline Cellular Dyes, Fluorescent Properties, Cellular Localization and Cytotoxic Behavior

PloS one, 2015-06, Vol.10 (6), p.e0131210-e0131210

2015

Volltextzugriff (PDF)

Stereoselective property of 20(S)-protopanaxadiol ocotillol type epimers affects its absorption and also the inhibition of P-glycoprotein

PloS one, 2014-06, Vol.9 (6), p.e98887

2014

Volltextzugriff (PDF)

1 – 25 von 19.099

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Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies

Pyrimidone inhibitors targeting Chikungunya Virus nsP3 macrodomain by fragment-based drug design

Equations for estimating binary mixture toxicity: 3-methyl-2-butanone with a series of electrophiles

Contribution of amino acids in the active site of dipeptidyl peptidase 4 to the catalytic action of the enzyme

cis-Decalin-containing tetramic acids as inhibitors of insect steroidogenic glutathione S-transferase Noppera-bo

Epigenetic regulation in colorectal cancer: The susceptibility of microRNAs 145, 143 and 133b to DNA demethylation and histone deacetylase inhibitors

The exquisite specificity of human protein arginine methyltransferase 7 (PRMT7) toward Arg-X-Arg sites

Exploring functional and structural features of chemically related natural prenylated hydroquinone and benzoic acid from Piper crassinervium (Piperaceae) on bacterial peroxiredoxin inhibition

Label-free affinity screening, design and synthesis of inhibitors targeting the Mycobacterium tuberculosis L-alanine dehydrogenase

Effect of the LSD1 inhibitor RN-1 on γ-globin and global gene expression during erythroid differentiation in baboons (Papio anubis)

The impact of natural products upon modern drug discovery

Binding of omeprazole to protein targets identified by monoclonal antibodies

The ubiquinone synthesis pathway is a promising drug target for Chagas disease

Expression of epigenetic pathway related genes in association with PD-L1, ER/PgR and MLH1 in endometrial carcinoma

Multitarget Drugs: an Epigenetic Epiphany

One-pot three component synthesis of substituted dihydropyrimidinones using fruit juices as biocatalyst and their biological studies

Piperidine scaffold as the novel P2-ligands in cyclopropyl-containing HIV-1 protease inhibitors: Structure-based design, synthesis, biological evaluation and docking study

Marine sediment-derived Streptomyces bacteria from British Columbia, Canada are a promising microbiota resource for the discovery of antimicrobial natural products

Practical spectrophotometric assay for the dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase, a potential antibiotic target

Epigenetics: the first 25 centuries

Pharmacological inhibition of polysialyltransferase ST8SiaII modulates tumour cell migration

Finding Potent Sirt Inhibitor in Coffee: Isolation, Confirmation and Synthesis of Javamide-II (N-Caffeoyltryptophan) as Sirt1/2 Inhibitor

Scaffold hopping from (5-hydroxymethyl) isophthalates to multisubstituted pyrimidines diminishes binding affinity to the C1 domain of protein kinase C

Synthesis of New Styrylquinoline Cellular Dyes, Fluorescent Properties, Cellular Localization and Cytotoxic Behavior

Stereoselective property of 20(S)-protopanaxadiol ocotillol type epimers affects its absorption and also the inhibition of P-glycoprotein

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