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Histamine and its receptors

British journal of pharmacology, 2006-01, Vol.147 (S1), p.S127-S135

2006

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Analogue-based Drug Discovery

1. Aufl., 2006

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The slow afterhyperpolarization: a target of β1-adrenergic signaling in hippocampus-dependent memory retrieval

The Journal of neuroscience, 2013-03, Vol.33 (11), p.5006-5016

2013

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Molecular features of the prazosin molecule required for activation of Transport-P

Bioorganic & medicinal chemistry, 2008-08, Vol.16 (15), p.7254-7263

2008

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Analogue-based Drug Discovery III

1. Aufl., 2013

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Protean agonism at histamine H3 receptors in vitro and in vivo

Proceedings of the National Academy of Sciences - PNAS, 2003-09, Vol.100 (19), p.11086-11091

2003

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Analogue-based drug discovery II

1, 2010

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Refined Docking as a Valuable Tool for Lead Optimization: Application to Histamine H3 Receptor Antagonists

Archiv der Pharmazie (Weinheim), 2008-10, Vol.341 (10), p.610-623

2008

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Enhancement of Hippocampal Pyramidal Cell Excitability by the Novel Selective Slow-Afterhyperpolarization Channel Blocker 3-(Triphenylmethylaminomethyl)pyridine (UCL2077)

Molecular pharmacology, 2006-11, Vol.70 (5), p.1494-1502

2006

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Introduction to Biological and Small Molecule Drug Research and Development: Theory and Case Studies

1, 2013

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Further studies on bis-charged tetraazacyclophanes as potent inhibitors of small conductance Ca(2+)-activated K+ channels

European journal of medicinal chemistry, 2013-05, Vol.63, p.907-923

2013

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Search for the pharmacophore in prazosin for Transport-P

Bioorganic & medicinal chemistry, 2005-06, Vol.13 (11), p.3681-3689

2005

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Personal reflections on Sir James Black (1924-2010) and histamine

Inflammation research, 2011, Vol.60 (1), p.103-110

Ganellin, C. Robin

2011

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Structural variations of 1-(4-(phenoxymethyl)benzyl)piperidines as nonimidazole histamine H3 receptor antagonists

Bioorganic & medicinal chemistry, 2004-05, Vol.12 (10), p.2727-2736

2004

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Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)

Pure and applied chemistry, 2013-07, Vol.85 (8), p.1725-1758

2013

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The Dictionary of Drugs: Chemical Data, Structures and Bibliographies

1, 1990

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Synthesis of novel ketoconazole derivatives as inhibitors of the human Pregnane X Receptor (PXR; NR1I2; also termed SXR, PAR)

Bioorganic & medicinal chemistry, 2008-07, Vol.18 (14), p.3974-3977

2008

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Meta-Substituted Aryl(thio)ethers as Potent Partial Agonists (or Antagonists) for the Histamine H3 Receptor Lacking a Nitrogen Atom in the Side Chain

Journal of medicinal chemistry, 2004-06, Vol.47 (12), p.3264-3274

2004

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Synthesis and pharmacological testing of polyaminoquinolines as blockers of the apamin-sensitive Ca2+ activated K+ channel (SKCa)

Bioorganic & medicinal chemistry, 2007-08, Vol.15 (16), p.5457-5479

2007

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Synthesis, Molecular Modeling, and Pharmacological Testing of Bis-Quinolinium Cyclophanes: Potent, Non-Peptidic Blockers of the Apamin-Sensitive Ca2+-Activated K+ Channel

Journal of medicinal chemistry, 2000-02, Vol.43 (3), p.420-431

2000

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Defining determinant molecular properties for the blockade of the apamin-sensitive SKCa channel in guinea-pig hepatocytes: the influence of polarizability and molecular geometry

Bioorganic & medicinal chemistry letters, 2004-08, Vol.14 (15), p.4031-4035

2004

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The sleep lipid oleamide may represent an endogenous anticonvulsant: an in vitro comparative study in the 4-aminopyridine rat brain-slice model

Neuropharmacology, 2004-03, Vol.46 (4), p.541-554

2004

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Partial structures of ketoconazole as modulators of the large conductance calcium-activated potassium channel (BK Ca)

Bioorganic & medicinal chemistry letters, 2006-02, Vol.16 (4), p.887-890

2006

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Novel Nonimidazole Histamine H3 Receptor Antagonists: 1-(4-(Phenoxymethyl)benzyl)piperidines and Related Compounds

Journal of medicinal chemistry, 2003-04, Vol.46 (8), p.1523-1530

2003

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Characterization and inhibition of a cholecystokinin-inactivating serine peptidase

Nature (London), 1996-04, Vol.380 (6573), p.403-409

1996

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Histamine and its receptors

Analogue-based Drug Discovery

The slow afterhyperpolarization: a target of β1-adrenergic signaling in hippocampus-dependent memory retrieval

Molecular features of the prazosin molecule required for activation of Transport-P

Analogue-based Drug Discovery III

Protean agonism at histamine H3 receptors in vitro and in vivo

Analogue-based drug discovery II

Refined Docking as a Valuable Tool for Lead Optimization: Application to Histamine H3 Receptor Antagonists

Enhancement of Hippocampal Pyramidal Cell Excitability by the Novel Selective Slow-Afterhyperpolarization Channel Blocker 3-(Triphenylmethylaminomethyl)pyridine (UCL2077)

Introduction to Biological and Small Molecule Drug Research and Development: Theory and Case Studies

Further studies on bis-charged tetraazacyclophanes as potent inhibitors of small conductance Ca(2+)-activated K+ channels

Search for the pharmacophore in prazosin for Transport-P

Personal reflections on Sir James Black (1924-2010) and histamine

Structural variations of 1-(4-(phenoxymethyl)benzyl)piperidines as nonimidazole histamine H3 receptor antagonists

Glossary of terms used in medicinal chemistry. Part II (IUPAC Recommendations 2013)

The Dictionary of Drugs: Chemical Data, Structures and Bibliographies

Synthesis of novel ketoconazole derivatives as inhibitors of the human Pregnane X Receptor (PXR; NR1I2; also termed SXR, PAR)

Meta-Substituted Aryl(thio)ethers as Potent Partial Agonists (or Antagonists) for the Histamine H3 Receptor Lacking a Nitrogen Atom in the Side Chain

Synthesis and pharmacological testing of polyaminoquinolines as blockers of the apamin-sensitive Ca2+ activated K+ channel (SKCa)

Synthesis, Molecular Modeling, and Pharmacological Testing of Bis-Quinolinium Cyclophanes: Potent, Non-Peptidic Blockers of the Apamin-Sensitive Ca2+-Activated K+ Channel

Defining determinant molecular properties for the blockade of the apamin-sensitive SKCa channel in guinea-pig hepatocytes: the influence of polarizability and molecular geometry

The sleep lipid oleamide may represent an endogenous anticonvulsant: an in vitro comparative study in the 4-aminopyridine rat brain-slice model

Partial structures of ketoconazole as modulators of the large conductance calcium-activated potassium channel (BK Ca)

Novel Nonimidazole Histamine H3 Receptor Antagonists: 1-(4-(Phenoxymethyl)benzyl)piperidines and Related Compounds

Characterization and inhibition of a cholecystokinin-inactivating serine peptidase

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