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Natural HDAC Inhibitors for Epigenetic Combating of Cancer Progression

Ahmad Ganai, Shabir

1, 2023

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Histone Deacetylase (HDAC) Inhibitors - emerging roles in neuronal memory, learning, synaptic plasticity and neural regeneration

Current neuropharmacology, 2016-01, Vol.14 (1), p.55-71

2016

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Panobinostat: The Small Molecule Metalloenzyme Inhibitor with Marvelous Anticancer Activity

Current topics in medicinal chemistry, 2016-01, Vol.16 (4), p.427

Ganai, Shabir Ahmad

2016

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Isolation and characterization of a new cold-active protease from psychrotrophic bacteria of Western Himalayan glacial soil

Scientific reports, 2021-06, Vol.11 (1), p.12768-14, Article 12768

2021

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Novel Approaches Towards Designing of Isoform-Selective Inhibitors Against Class II Histone Deacetylases: The Acute Requirement for Targetted Anticancer Therapy

Current topics in medicinal chemistry, 2016-09, Vol.16 (22), p.2441

Ganai, Shabir Ahmad

2016

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Plant Derived Inhibitor Sulforaphane in Combinatorial Therapy Against Therapeutically Challenging Pancreatic Cancer

Anti-cancer agents in medicinal chemistry, 2017-01, Vol.17 (3), p.365

2017

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Anticancer activity of the plant flavonoid luteolin against preclinical models of various cancers and insights on different signalling mechanisms modulated

Phytotherapy research, 2021-07, Vol.35 (7), p.3509-3532

2021

Volltextzugriff (PDF)

Histone Deacetylase Inhibitors in Combinatorial Anticancer Therapy

Ganai, Shabir Ahmad

1st Edition 2020, 2020

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Plant flavone Chrysin as an emerging histone deacetylase inhibitor for prosperous epigenetic‐based anticancer therapy

Phytotherapy research, 2021-02, Vol.35 (2), p.823-834

2021

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Molecular and functional characterization of protease from psychrotrophic Bacillus sp. HM49 in North-western Himalaya

PloS one, 2023-03, Vol.18 (3), p.e0283677-e0283677

2023

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Histone Deacetylase Inhibitors -- Epidrugs for Neurological Disorders

Ganai, Shabir Ahmad

1st ed. 2019., 2019

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Molecular characterization of lipase from a psychrotrophic bacterium Pseudomonas sp. CRBC14

Current genetics, 2022-04, Vol.68 (2), p.243-251

2022

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Characterizing binding intensity and energetic features of histone deacetylase inhibitor pracinostat towards class I HDAC isozymes through futuristic drug designing strategy

In silico pharmacology, 2021-02, Vol.9 (1), p.18, Article 18

Ganai, Shabir Ahmad

2021

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Comparative structural study of selective and non-selective NSAIDs against the enzyme cyclooxygenase-2 through real-time molecular dynamics linked to post-dynamics MM-GBSA and e-pharmacophores mapping

Journal of molecular modeling, 2023-06, Vol.29 (6), p.192-192, Article 192

2023

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Biochemical Characterization and Functional Analysis of Heat Stable High Potential Protease of Bacillus amyloliquefaciens Strain HM48 from Soils of Dachigam National Park in Kashmir Himalaya

Biomolecules (Basel, Switzerland), 2021-01, Vol.11 (1), p.117

2021

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Identification of plant based potential antifungal compounds against BMK-1 protein of Bipolaris oryzae using molecular docking approach

Scientific reports, 2024-07, Vol.14 (1), p.15665-16, Article 15665

2024

Volltextzugriff (PDF)

Combinatorial In Silico Strategy towards Identifying Potential Hotspots during Inhibition of Structurally Identical HDAC1 and HDAC2 Enzymes for Effective Chemotherapy against Neurological Disorders

Frontiers in molecular neuroscience, 2017-11, Vol.10, p.357-357

2017

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Therapeutic strategies against hDOT1L as a potential drug target in MLL-rearranged leukemias

Clinical epigenetics, 2020-05, Vol.12 (1), p.73-73, Article 73

2020

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Isolation, purification and characterization of naturally derived Crocetin beta-d-glucosyl ester from Crocus sativus L. against breast cancer and its binding chemistry with ER-alpha/HDAC2

Saudi journal of biological sciences, 2020-03, Vol.27 (3), p.975-984

2020

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Comprehensive biochemical approach for understanding the interaction between host “common bean” and pathogen “Colletotrichum lindemuthianum” causing bean anthracnose

Physiology and molecular biology of plants, 2023-12, Vol.29 (12), p.2005-2020

2023

Volltextzugriff (PDF)

Plant-derived flavone Apigenin: The small-molecule with promising activity against therapeutically resistant prostate cancer

Biomedicine & pharmacotherapy, 2017-01, Vol.85, p.47-56

Ganai, Shabir Ahmad

2017

Volltextzugriff (PDF)

Strategy for enhancing the therapeutic effi cacy of histone deacetylase inhibitor dacinostat: the novel paradigm to tackle monotonous cancer chemoresistance

Archives of Pharmacal Research, 2021, 44(9), , pp.839-849

Shabir Ahmad Ganai

2021

Volltextzugriff (PDF)

Histone deacetylase inhibitor sulforaphane: The phytochemical with vibrant activity against prostate cancer

Biomedicine & pharmacotherapy, 2016-07, Vol.81, p.250-257

Ganai, Shabir Ahmad

2016

Volltextzugriff (PDF)

Histone deacetylase inhibitor givinostat: the small-molecule with promising activity against therapeutically challenging haematological malignancies

Journal of chemotherapy (Florence), 2016-07, Vol.28 (4), p.247-254

Ganai, Shabir Ahmad

2016

Volltextzugriff (PDF)

Histone deacetylase inhibitor pracinostat in doublet therapy: a unique strategy to improve therapeutic efficacy and to tackle herculean cancer chemoresistance

Pharmaceutical biology, 2016-09, Vol.54 (9), p.1926-1935

Ganai, Shabir Ahmad

2016

Volltextzugriff (PDF)

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Natural HDAC Inhibitors for Epigenetic Combating of Cancer Progression

Histone Deacetylase (HDAC) Inhibitors - emerging roles in neuronal memory, learning, synaptic plasticity and neural regeneration

Panobinostat: The Small Molecule Metalloenzyme Inhibitor with Marvelous Anticancer Activity

Isolation and characterization of a new cold-active protease from psychrotrophic bacteria of Western Himalayan glacial soil

Novel Approaches Towards Designing of Isoform-Selective Inhibitors Against Class II Histone Deacetylases: The Acute Requirement for Targetted Anticancer Therapy

Plant Derived Inhibitor Sulforaphane in Combinatorial Therapy Against Therapeutically Challenging Pancreatic Cancer

Anticancer activity of the plant flavonoid luteolin against preclinical models of various cancers and insights on different signalling mechanisms modulated

Histone Deacetylase Inhibitors in Combinatorial Anticancer Therapy

Plant flavone Chrysin as an emerging histone deacetylase inhibitor for prosperous epigenetic‐based anticancer therapy

Molecular and functional characterization of protease from psychrotrophic Bacillus sp. HM49 in North-western Himalaya

Histone Deacetylase Inhibitors -- Epidrugs for Neurological Disorders

Molecular characterization of lipase from a psychrotrophic bacterium Pseudomonas sp. CRBC14

Characterizing binding intensity and energetic features of histone deacetylase inhibitor pracinostat towards class I HDAC isozymes through futuristic drug designing strategy

Comparative structural study of selective and non-selective NSAIDs against the enzyme cyclooxygenase-2 through real-time molecular dynamics linked to post-dynamics MM-GBSA and e-pharmacophores mapping

Biochemical Characterization and Functional Analysis of Heat Stable High Potential Protease of Bacillus amyloliquefaciens Strain HM48 from Soils of Dachigam National Park in Kashmir Himalaya

Identification of plant based potential antifungal compounds against BMK-1 protein of Bipolaris oryzae using molecular docking approach

Combinatorial In Silico Strategy towards Identifying Potential Hotspots during Inhibition of Structurally Identical HDAC1 and HDAC2 Enzymes for Effective Chemotherapy against Neurological Disorders

Therapeutic strategies against hDOT1L as a potential drug target in MLL-rearranged leukemias

Isolation, purification and characterization of naturally derived Crocetin beta-d-glucosyl ester from Crocus sativus L. against breast cancer and its binding chemistry with ER-alpha/HDAC2

Comprehensive biochemical approach for understanding the interaction between host “common bean” and pathogen “Colletotrichum lindemuthianum” causing bean anthracnose

Plant-derived flavone Apigenin: The small-molecule with promising activity against therapeutically resistant prostate cancer

Strategy for enhancing the therapeutic effi cacy of histone deacetylase inhibitor dacinostat: the novel paradigm to tackle monotonous cancer chemoresistance

Histone deacetylase inhibitor sulforaphane: The phytochemical with vibrant activity against prostate cancer

Histone deacetylase inhibitor givinostat: the small-molecule with promising activity against therapeutically challenging haematological malignancies

Histone deacetylase inhibitor pracinostat in doublet therapy: a unique strategy to improve therapeutic efficacy and to tackle herculean cancer chemoresistance

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